Sleep Disturbance Clinical Trials

26 studies are recruiting for sleep disturbance in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

By city

Studies now recruiting

1. Sleep Promotion Program Primary Care

   Investigators developed a brief, scalable, behavioral Sleep Promotion Program (SPP) for adolescents with short sleep duration and sleep-wake irregularity, which relies on two individual sessions and smart phone technology to deliver evidence-based strategies. This R34 will test the feasibility and …

   Stage

   Not phased

   Ages

   12 to 18

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT06240325 on ClinicalTrials.gov

2. RCT of a Weighted Blanket to Reduce Pain in Veterans With Chronic Pain

   Chronic pain is a major health concern for returning Veterans and is associated with decreases in quality of life. In addition, chronic pain is often accompanied by significant disturbance in sleep. Sensory interventions may offer effective, low-cost complementary tools for chronic pain and sleep d…

   Stage

   Not phased

   Ages

   18 and older

   Site

   VA San Diego Healthcare System, San Diego, CA, San Diego, California

   Locations

   2 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT05963607 on ClinicalTrials.gov

3. The Power Down Pilot Study: A Novel Bedtime Manipulation Protocol

   The goal of this pilot intervention study is to examine the feasibility and acceptability of a novel bedtime manipulation protocol called "The Power Down" for autistic youth, ages 6-10. The main questions it aims to answer are: 1. Is the Power Down feasible for caregivers to do each night? 2. Do th…

   Stage

   Not phased

   Ages

   6 to 10

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT06386029 on ClinicalTrials.gov

4. Medications for Opioid Use Disorder Photosensitive Retinal Ganglion Cell Function, Sleep, and Circadian Rhythms: Implications for Treatment

   Opioid use disorder (OUD) is a treatable medical illness with three medications FDA approved for treatment. However, persons with OUD report significant sleep disturbance, even when treated with medications for opioid use disorder, leading to high rates of relapse. In this project, we will investig…

   Stage

   Not phased

   Ages

   18 to 80

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT06104280 on ClinicalTrials.gov

5. Developing Restful Environments and Management Strategies for Pediatric Stem Cell Transplant Patients

   Pediatric patients undergoing stem cell transplant (SCT) are hospitalized for extended periods and are at high risk for sleep disturbances. In order to begin to address the environmental issues that SCT recipients face during inpatient hospitalizations, investigators will conduct a single arm pilot…

   Stage

   Not phased

   Ages

   9 to 17

   Site

   Boston Children's Hospital, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Dana-Farber Cancer Institute

   See if you can join NCT06468618 on ClinicalTrials.gov

6. Sleep More, Stress Less: 90-Day Trial of Neuralli Mood

   This decentralized, single-arm study evaluates the effects of 90 days of daily Neuralli Mood supplementation on perceived stress, sleep disturbance, mood, anxiety, depressive symptoms, happiness, and occupational burnout in adults experiencing stress or occasional sleep disruption. Participants ser…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Efforia - Decentralized United States Study, New York, New York

   Run by

   Efforia, Inc

   See if you can join NCT07717385 on ClinicalTrials.gov

7. SPARK Healthy Sleep

   SPARK-Healthy Sleep is a digital mental health intervention designed to help college students who may be at risk for psychosis and experience sleep problems. About 1 in 4 college students report psychotic-like experiences (such as hearing voices or feeling paranoid), and these students often have p…

   Stage

   Not phased

   Ages

   18 to 65

   Site

   Indiana University, Indianapolis, Indiana

   Run by

   Indiana University

   See if you can join NCT07119268 on ClinicalTrials.gov

8. Sleep and Circadian Interventions for College Students at High Risk of Suicide

   The purpose of this study is to examine the extent to which delivering sleep and circadian focused interventions in addition to evidenced based psychiatric care for depression and suicide risk may contribute to decreasing suicide risk among high risk young adults. Investigators will evaluate three …

   Stage

   Not phased

   Ages

   18 to 25

   Site

   Western Psychiatric Hospital/University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT07346014 on ClinicalTrials.gov

9. Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone

   To investigate the effect of trazodone on sleep, hippocampal-dependent memory and hippocampal excitability. The investigators hypothesize that trazodone will improve total sleep time and proportion of time in Slow Wave Sleep (SWS).

   Stage

   Phase 2

   Ages

   55 and older

   Site

   Johns Hopkins Hospital, Baltimore, Maryland

   Run by

   Johns Hopkins University

   See if you can join NCT05282550 on ClinicalTrials.gov

10. Weighted Blanket Use for Adults With Chronic Pain

    Chronic pain is a common condition that can affect sleep, daily functioning, and overall quality of life. Many individuals living with chronic pain seek non-medication approaches to help manage their symptoms. Weighted blankets are commonly used to promote relaxation and comfort during sleep, but t…

    Stage

    Not phased

    Ages

    18 and older

    Site

    National University of Natural Medicine, Portland, Oregon

    Run by

    National University of Natural Medicine

    See if you can join NCT07498491 on ClinicalTrials.gov

11. Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

    The goal of this clinical trial is to adapt a sleep intervention for individuals representative of all demographic groups, including those who are at the highest risk for suicidal behavior. Sleep difficulties are a promising target for youth with suicidal thoughts and behavior to focus on as a prev…

    Stage

    Not phased

    Ages

    12 to 18

    Site

    Childrens Hospital of Philadelphia, Philadelphia, Pennsylvania

    Locations

    2 in total

    Run by

    University of Pittsburgh

    See if you can join NCT06963463 on ClinicalTrials.gov

12. Using Dupilumab to Improve Circadian Function, Sleep and Pruritus in Children With Moderate/Severe Atopic Dermatitis

    Single center, prospective, Open label study of sleep, pruritus and circadian function pre/post 12-weeks of dupilumab treatment in children 6-17 years old

    Stage

    Phase 4

    Ages

    6 to 17

    Site

    Lurie Children's Hospital/Northwestern University, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT05042258 on ClinicalTrials.gov

13. Home Apnea Testing in CHildren Trial

    This clinical trial will compare home sleep apnea testing with the gold standard in-lab polysomnography in terms of 1) accuracy, 2) therapeutic decision-making, and 3) parent/child acceptability in children referred for evaluation of obstructive sleep apnea.

    Stage

    Not phased

    Ages

    5 to 12

    Site

    The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

    Run by

    Children's Hospital of Philadelphia

    See if you can join NCT05382754 on ClinicalTrials.gov

14. PICU-related Sleep and Circadian Dysregulation Pilot Study

    A single center pilot trial investigating the feasibility of using actigraphy and salivary melatonin levels to measure the sleep and circadian rhythm of critically ill children aged 3 to 6 years old. This study will also measure the feasibility of providing daytime light exposure as well as restric…

    Stage

    Not phased

    Ages

    3 to 6

    Site

    John R. Oishei Children's Hospital, Buffalo, New York

    Run by

    State University of New York at Buffalo

    See if you can join NCT06505447 on ClinicalTrials.gov

15. VR-PMR for Post-Burn Symptoms

    The goal of this clinical trial is to learn whether progressive muscle relaxation (PMR), delivered either alone or enhanced with virtual reality (VR), can help treat chronic symptom, such as pain, itch, anxiety, sleep disturbances, and fatigue, in adult burn survivors. The main questions it aims to…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Johns Hopkins Bayview Medical Center, Baltimore, Maryland

    Run by

    Johns Hopkins University

    See if you can join NCT07317271 on ClinicalTrials.gov

16. Sleep Enhancement for Older Adults Living With Memory Loss And Their Care Partners

    The purpose of this study is to determine if a 6-week videoconference intervention to teach skills to improve sleep is practical, acceptable, and helpful to persons living with memory loss, cognitive impairment, and/or dementia and care partners, individually or together.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Emory Healthcare System, Atlanta, Georgia

    Run by

    Emory University

    See if you can join NCT06250725 on ClinicalTrials.gov

17. Sleep and Central Auditory Processing Disorder in Autism Spectrum Disorder

    The proposed study aims to understand poor sleep as a possible cause to CAPD in children and adolescents with ASD (ASD+) compared to ASD youth without CAPD (ASD-), using both caregiver-report and objective clinician administered measures. Additionally, the study will aim to understand the complex r…

    Stage

    Not phased

    Ages

    6 to 17

    Site

    Loma Linda University Health, Loma Linda, California

    Run by

    Loma Linda University

    See if you can join NCT06059352 on ClinicalTrials.gov

18. A Study to Evaluate the Effects of a Supplement on the Side Effects Associated With Stimulant Medications

    This is a hybrid, two-arm, triple-blind, placebo-controlled, randomized clinical trial evaluating the efficacy of the Stasis supplement on reducing oxidative stress, cortisol levels, and side effects associated with stimulant medications used for ADHD over a three-month period in adults.

    Stage

    Not phased

    Ages

    18 to 55

    Site

    Citruslabs, Las Vegas, Nevada

    Run by

    Outliers, Inc.

    See if you can join NCT07380412 on ClinicalTrials.gov

19. Art Therapy and Emotional Well Being in Military Populations With Posttraumatic Stress Symptoms

    Art therapy is used across the Military Health System for treatment of posttraumatic symptoms, but there is limited research on how art therapy is able to restore emotional expression and regulation in service members. This research hopes to learn about the effects of art therapy on emotional expre…

    Stage

    Not phased

    Ages

    18 to 64

    Site

    National Intrepid Center of Excellence, Bethesda, Maryland

    Locations

    2 in total

    Run by

    Walter Reed National Military Medical Center

    See if you can join NCT05414708 on ClinicalTrials.gov

20. The Iowa ACEs and Sleep Cohort and Manipulating Sleep in Young Adults With ACEs Studies

    The overall purpose of this study is to understand the role of disrupted sleep in the association of exposure to early life adversity (adverse childhood experiences (ACEs)) with vascular endothelial (dys)function. In Aim 1 (The Iowa ACEs and Sleep Cohort Study), the investigators will utilize a cro…

    Stage

    Not phased

    Ages

    18 to 29

    Site

    Integrative Laboratory of Applied Physiology and Lifestyle Medicine, Iowa City, Iowa

    Run by

    Nathaniel Jenkins

    See if you can join NCT06454344 on ClinicalTrials.gov

21. UCLA REST Study (REsearch on Sleep Techniques)

    Sleep disturbance has a range of negative effects on psychosocial and biological processes important for academic and social success as well as mental and physical health among adolescents and young adults. Limited, inconsistent, and poor quality sleep lead to anxiety, depressive feelings, loneline…

    Stage

    Not phased

    Ages

    18 to 22

    Site

    University of California, Los Angeles, Los Angeles, California

    Run by

    University of California, Los Angeles

    See if you can join NCT05576090 on ClinicalTrials.gov

22. A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors

    Up to 25% of intensive care unit (ICU) survivors experience cognitive impairment comparable in severity to mild Alzheimer's disease and related dementias after hospital discharge. Older ICU survivors (ages 60 and older) are at highest risk for delirium and subsequent cognitive impairment, which con…

    Stage

    Not phased

    Ages

    60 and older

    Site

    University of Washington, Seattle, Washington

    Run by

    University of Washington

    See if you can join NCT06411561 on ClinicalTrials.gov

23. The Acute T-Rex (Timing of Resistance Exercise) Study

    The primary aim of this study is to evaluate if a single bout of AM vs PM resistance exercise has different effects on insulin sensitivity and sleep. A randomized cross-over trial be used to compare resistance exercise at two different times of the day. Each condition will take place in a laborator…

    Stage

    Not phased

    Ages

    50 to 74

    Site

    University of Utah HPER E Buildling, Salt Lake City, Utah

    Run by

    University of Utah

    See if you can join NCT06366399 on ClinicalTrials.gov

24. Improving Maternal Sleep and Mental Health

    The goal of this clinical trial is to test the effectiveness of a Smart Bassinet to prevent/mitigate postpartum mood disorders by augmenting maternal sleep and/or enhancing infant sleep. The investigators will conduct a 2-arm randomized controlled trial (RCT) to compare infant and maternal sleep of…

    Stage

    Not phased

    Ages

    18 to 45

    Site

    University of Colorado Colorado Springs, Colorado Springs, Colorado

    Run by

    University of Colorado, Colorado Springs

    See if you can join NCT06544941 on ClinicalTrials.gov

25. The Dream Team: Testing Implementation of a Sleep Intervention for Perinatal Women Delivered by Direct Care Workers

    Insufficient and disrupted sleep are rarely addressed in expectant and new mothers, despite evidence that disturbed sleep is a modifiable risk factor for negative health outcomes for mothers and their children. In this study the investigators will adapt, refine, and pilot test the implementation of…

    Stage

    Not phased

    Ages

    18 to 99

    Site

    Rhode Island Hospital, Providence, Rhode Island

    Run by

    Rhode Island Hospital

    See if you can join NCT06737055 on ClinicalTrials.gov