Sickle Cell Disease Clinical Trials in Flowood, Mississippi

5 studies are recruiting for sickle cell disease in Flowood, Mississippi right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)

    A phase III, multi-center, randomized, placebo-controlled, double-blind study to assess efficacy and safety of crizanlizumab (5 mg/kg) versus placebo, with or without hydroxyurea/hydroxycarbamide therapy, in adolescent and adult Sickle Cell Disease patients with frequent vaso-occlusive crises.

    Stage
    Phase 3
    Ages
    12 to 100
    Site
    Southern Specialty Research, Flowood, Mississippi
    Locations
    35 in total
    Run by
    Novartis Pharmaceuticals

    See if you can join NCT06439082 on ClinicalTrials.gov

  2. A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD

    The purpose of this study is to evaluate the safety, tolerability, efficacy, pharmacokinetics and pharmacodynamics of osivelotor.

    Stage
    Phase 2
    Ages
    12 and older
    Site
    Southern Specialty Research, Flowood, Mississippi
    Locations
    80 in total
    Run by
    Pfizer

    See if you can join NCT05431088 on ClinicalTrials.gov

  3. Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)

    This is a phase 2a, global, multicenter, randomized, double-blind, placebo-controlled study investigating the safety of anumigilimab administered subcutaneously (SC) at the maximum tolerated dose (MTD) in adult participants with SCD. The primary aim of the study is to assess the safety of anumigili…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Southern Specialty Research, Flowood, Mississippi
    Locations
    16 in total
    Run by
    CSL Behring

    See if you can join NCT07224360 on ClinicalTrials.gov

  4. A Study to Investigate the Effect of Mitapivat on Transfusion Burden in Subjects With Sickle Cell Disease (SCD)

    The primary objective of this study is to determine the effect of mitapivat versus placebo on the need for transfusions in subjects with SCD.

    Stage
    Phase 3
    Ages
    12 and older
    Site
    Southern Specialty Clinic, Flowood, Mississippi
    Locations
    3 in total
    Run by
    Agios Pharmaceuticals, Inc.

    See if you can join NCT07656415 on ClinicalTrials.gov

  5. The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease

    This is a multicenter, randomized, double-blind, placebo-controlled, parallel-group, flexible-adaptive, group-sequential study (Part A), followed by an open-label LTE period (Part B) to investigate the efficacy, and safety of rilzabrutinib in participants with sickle-cell disease (SCD). Study detai…

    Stage
    Phase 3
    Ages
    10 to 65
    Site
    Southern Specialty Research- Site Number : 8400059, Flowood, Mississippi
    Locations
    53 in total
    Run by
    Sanofi

    See if you can join NCT06975865 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.