Sickle Cell Disease Clinical Trials in Cleveland, Ohio

6 studies are recruiting for sickle cell disease in Cleveland, Ohio right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

   This study is conducted to confirm whether etavopivat works well at reducing the number of Vaso-occlusive crisis VOCs (sickle cell pain crises) caused by obstructions in blood vessels in adults and adolescents living with sickle cell disease. The study will also evaluate how well etavopivat can red…

   Stage

   Phase 3

   Ages

   12 and older

   Site

   Univ Hosp Cleveland Med Ctr, Cleveland, Ohio

   Locations

   175 in total

   Run by

   Novo Nordisk A/S

   See if you can join NCT06612268 on ClinicalTrials.gov

2. Sickle Cell Disease Biofluid Chip Technology (SCD BioChip)

   'Sickle-shaped' anemia was first clinically described in the US in 1910, and the mutated heritable sickle hemoglobin molecule was identified in 1949. The pathophysiology of SCD is a consequence of abnormal polymerization of sickle hemoglobin (HbS) and its effects on red cell membrane properties, sh…

   Stage

   Not phased

   Ages

   12 and older

   Site

   University Hospitals Case Medical Center, Cleveland, Ohio

   Run by

   University Hospitals Cleveland Medical Center

   See if you can join NCT02824471 on ClinicalTrials.gov

3. ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

   In parallel with the growth of ATHN's clinical studies, the number of new therapies for all blood disorders is increasing significantly. Some of the recently FDA-approved therapies for congenital and acquired hematologic conditions have not yet demonstrated long-term safety and effectiveness beyond…

   Stage

   Not phased

   Ages

   Any age

   Site

   University Hospitals Health System Cleveland, Cleveland, Ohio

   Locations

   76 in total

   Run by

   American Thrombosis and Hemostasis Network

   See if you can join NCT04398628 on ClinicalTrials.gov

4. MULTIsite Feasibility of MUSIc Therapy to Address Quality Of Life in Sickle Cell Disease

   This is a multi-site, multi-visit feasibility RCT of music therapy (MT) among adolescent and adult patients (aged 14 and older) with sickle cell disease (SCD). Subjects will be randomized into one of three groups, either (1) 6 visits of in- person MT (InMT:); (2) 1 visit of in-person MT and 5 visit…

   Stage

   Not phased

   Ages

   14 and older

   Site

   UH Seidman Cancer Center Adult SCD Clinic or UH Rainbow Babies and Children's Hospital Sickle Cell Anemia Center, Cleveland, Ohio

   Locations

   2 in total

   Run by

   University of California, Irvine

   See if you can join NCT06853158 on ClinicalTrials.gov

5. A Long-term Follow-up Study in Patients Who Received BEAM-101

   This is a Long-term Follow-up (LTFU) study in patients who received BEAM-101 in the parent study (Study BTX-AUT-001). Eligible patients who received BEAM-101 will be asked to participate in this LTFU study prior to completing Study BTX-AUT-001. Patients who enter into this study will be followed fo…

   Stage

   Not phased

   Ages

   14 to 37

   Site

   University Hospitals Clevland Medical Center, Cleveland, Ohio

   Locations

   17 in total

   Run by

   Beam Therapeutics Inc.

   See if you can join NCT07373639 on ClinicalTrials.gov

6. Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease

   The goal of this observational study is to help us understand more about the best ways to help individuals living with Sickle Cell Disease (SCD) get the best care. The main question it aims to answer is: How to find individuals unaffiliated from SCD specialist care use three distinct pathways? Once…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Cleveland Clinic, Cleveland, Ohio

   Locations

   9 in total

   Run by

   RTI International

   See if you can join NCT06385886 on ClinicalTrials.gov