Sickle Cell Disease Clinical Trials in Cincinnati, Ohio

8 studies are recruiting for sickle cell disease in Cincinnati, Ohio right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

   Etavopivat is a new medicine under development for treating blood disorders like sickle cell disease and thalassaemia. Sickle cell disease and thalassaemia are inherited blood disorders that affect haemoglobin. Haemoglobin is the protein that carries oxygen through the body. This study is looking i…

   Stage

   Phase 3

   Ages

   2 and older

   Site

   Cincinnati Child's Hsp Med Ctr, Cincinnati, Ohio

   Locations

   107 in total

   Run by

   Novo Nordisk A/S

   See if you can join NCT06609226 on ClinicalTrials.gov

2. A Phase 1b, Open-Label Study of DISC-3405 in Participants With Sickle Cell Disease (SCD)

   This is an open-label, multicenter, within-participant dose-escalation study examining up to 3 dose levels of DISC-3405 and will assess the safety, tolerability, PK, and PD of DISC 3405 in participants with sickle cell disease.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

   Locations

   9 in total

   Run by

   Disc Medicine, Inc

   See if you can join NCT07187973 on ClinicalTrials.gov

3. ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

   In parallel with the growth of ATHN's clinical studies, the number of new therapies for all blood disorders is increasing significantly. Some of the recently FDA-approved therapies for congenital and acquired hematologic conditions have not yet demonstrated long-term safety and effectiveness beyond…

   Stage

   Not phased

   Ages

   Any age

   Site

   Cincinnati Children's Hospital Medical Center, Hemophilia & Thrombosis Center, Cincinnati, Ohio

   Locations

   76 in total

   Run by

   American Thrombosis and Hemostasis Network

   See if you can join NCT04398628 on ClinicalTrials.gov

4. Integrative Medicine in Pain Management in Sickle Cell Disease, 2.0

   The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.

   Stage

   Not phased

   Ages

   14 to 80

   Site

   University of Cincinnati College of Medicine, Cincinnati, Ohio

   Run by

   University of Cincinnati

   See if you can join NCT06725550 on ClinicalTrials.gov

5. Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation

   The purpose of this research study is to document and understand the effects of hydroxyurea exposure for women with SCD and their babies, during both gestation and lactation.

   Stage

   Not phased

   Ages

   Any age

   Site

   Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

   Run by

   Children's Hospital Medical Center, Cincinnati

   See if you can join NCT04093986 on ClinicalTrials.gov

6. Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones Trial

   The goal of this short term prospective Phase II study is to compare the effects of two alternate daily doses of zinc (25 and 40 mg/day) in 34 randomly assigned homozygous Sickle Cell Disease (SCD-SS) patients aged 15-40 years old. The main question it aims to answer is: Which biomarkers are most r…

   Stage

   Phase 2

   Ages

   15 to 40

   Site

   Cincinnati Children's Hospital, Cincinnati, Ohio

   Locations

   6 in total

   Run by

   University of California, San Francisco

   See if you can join NCT06260891 on ClinicalTrials.gov

7. Verifying Antibodies After Live Immunization Delivery (VALID): A Study of Measles Vaccine Immunogenicity in Children With Sickle Cell Disease

   The goal of this study is to learn if infants with sickle cell disease (SCD) develop adequate protection after measles vaccines. (not looking at any prolonged duration)

   Stage

   Not phased

   Ages

   0 to 6

   Site

   Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

   Locations

   3 in total

   Run by

   Children's Hospital Medical Center, Cincinnati

   See if you can join NCT07356050 on ClinicalTrials.gov

8. Integrative Training Program for Pediatric Sickle Cell Pain

   This research aims to answer the question: does a group training program specifically for teens with chronic sickle cell disease (SCD) pain that teaches skills to strengthen the mind and body help improve everyday functioning and reduce pain symptoms? The program will be tailored to address challen…

   Stage

   Not phased

   Ages

   12 to 18

   Site

   Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

   Locations

   4 in total

   Run by

   Emory University

   See if you can join NCT06691867 on ClinicalTrials.gov