Schizophrenia Clinical Trials in Pittsburgh, Pennsylvania

7 studies are recruiting for schizophrenia in Pittsburgh, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study to Evaluate the Long-term Safety and Tolerability of KarXT and KarX-EC for the Treatment of Schizophrenia and Autism-Related Irritability in Adolescents, Respectively

   The purpose of this study is to evaluate the long-term safety and tolerability of KarXT and KarX-EC for the treatment of Schizophrenia and autism-related irritability in adolescents, respectively

   Stage

   Phase 3

   Ages

   5 to 17

   Site

   Local Institution - 0150, Pittsburgh, Pennsylvania

   Locations

   91 in total

   Run by

   Karuna Therapeutics, Inc., a Bristol Myers Squibb company

   See if you can join NCT07424404 on ClinicalTrials.gov

2. Enhancing Prefrontal Oscillations and Working Memory in Early-course Schizophrenia

   This study will investigate the effects of intermittent Theta Burst Stimulation (iTBS) on natural oscillatory frequency of the dorsolateral prefrontal cortex (DLPFC) and working memory in early-course schizophrenia (EC-SCZ). Transcranial magnetic stimulation (TMS) will be used to evoke oscillatory …

   Stage

   Not phased

   Ages

   18 to 40

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   Fabio Ferrarelli

   See if you can join NCT05102929 on ClinicalTrials.gov

3. Anticholinergic Deprescription in Schizophrenia

   In this study, the investigators will examine whether a deprescription of unnecessary anticholinergic drugs (benztropine or trihexyphenidyl) can augment quality of life, functioning, and neurocognition in individuals who with schizophrenia. Individuals identified by clinical services who have unnee…

   Stage

   Phase 4

   Ages

   40 to 70

   Site

   UPMC Western Psychiatric Hospital/University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   Deepak K. Sarpal, M.D.

   See if you can join NCT06562608 on ClinicalTrials.gov

4. Acetazolamide for Treatment Resistant Schizophrenia

   This is a double blind adjunctive randomized controlled trial for schizophrenia using acetazolamide.

   Stage

   Phase 1

   Ages

   18 to 55

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Locations

   2 in total

   Run by

   Vishwajit Nimgaonkar, MD PhD

   See if you can join NCT04887792 on ClinicalTrials.gov

5. Exercise-based Program for Rehabilitation of Veterans With Severe Mental Illness

   This is a hybrid1, effectiveness-implementation study of yoga-based exercises (YE) as an adjunctive tool for rehabilitation among persons with Severe Mental Illness (SMI). The two-arm randomized controlled trial will compare the efficacy of YE compared to the Wellness Lifestyle Program (WLP). Prima…

   Stage

   Not phased

   Ages

   18 to 70

   Site

   VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh, Pennsylvania

   Run by

   VA Office of Research and Development

   See if you can join NCT05157620 on ClinicalTrials.gov

6. Restoring Spindle and Thalamocortical Efficiency in Early-Course Schizophrenia Patients Using Auditory Stimulation

   The purpose of this research is to identify differences in brain activity during sleep between health individuals and individuals with schizophrenia, schizophreniform, or schizoaffective disorder. This study will also investigate whether tones played during deep sleep can enhance specific features …

   Stage

   Not phased

   Ages

   18 to 40

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   Fabio Ferrarelli

   See if you can join NCT05956951 on ClinicalTrials.gov

7. Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia

   This is a double blind adjunctive randomized controlled trial for schizophrenia using cromoglicate.

   Stage

   Phase 1

   Ages

   18 to 65

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   Vishwajit Nimgaonkar, MD PhD

   See if you can join NCT03794076 on ClinicalTrials.gov