Sarcopenia Clinical Trials

17 studies are recruiting for sarcopenia in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. Muscle Aging Phenotypes in Childhood Cancer Survivors

   Childhood cancer survivors experience premature declines in muscle mass, strength, and physical function that contribute to morbidity and early mortality. The biological mechanisms driving these impairments are heterogeneous and poorly understood. This observational study aims to characterize disti…

   Stage

   Not phased

   Ages

   18 and older

   Site

   St. Jude Children's Research Hospital, Memphis, Tennessee

   Run by

   St. Jude Children's Research Hospital

   See if you can join NCT07531498 on ClinicalTrials.gov

2. Exercise and Nutritional Prehabilitation for Head and Neck Cancer Patients

   This study examines the acceptability, feasibility, and safety in developing a prehabilitation program for head and neck cancer patients. The purpose of this research is to access the safety and acceptability of using a prehabilitation program before head and neck cancer surgery.

   Stage

   Not phased

   Ages

   18 and older

   Site

   UC Davis Health, Sacramento, California

   Locations

   2 in total

   Run by

   University of California, Davis

   See if you can join NCT06722508 on ClinicalTrials.gov

3. C-Protein in Fatigue and Aging

   This study is investigating changes to the proteins in skeletal muscle that contribute to reduced muscle size and muscle function that occurs with aging.

   Stage

   Not phased

   Ages

   18 to 80

   Site

   University of Oregon, Eugene, Oregon

   Run by

   University of Oregon

   See if you can join NCT05926219 on ClinicalTrials.gov

4. Adverse Outcomes and Mortality in Liver Transplant

   Prospective natural history pilot study to explore the link between muscle composition using an MRI-based Muscle Assessment Score (MAsS) and adverse outcomes in liver transplant candidates.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic Arizona, Phoenix, Arizona

   Run by

   Mayo Clinic

   See if you can join NCT05477277 on ClinicalTrials.gov

5. Prehab and Creatine/Whey Supplementation in Frailty Among Patients With Cirrhosis

   Frailty and muscle health are important for patients with chronic liver disease. This study looks at the use of a digital prehabilitation app (HEAL-ME) plus creatine and whey protein combination supplementation on maintaining muscle health in patients with liver disease. The investigators anticipat…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California San Francisco, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT07029243 on ClinicalTrials.gov

6. MyokinE100 System: Closed Loop Electrical Muscle Stimulation to Mitigate ICU Acquired Weakness in Medical ICU Patients

   The goal of this clinical trial is to learn if a new medical device that sends electrical signals to the thigh muscles is safe and easy to use for people in the ICU (Intensive Care Unit) who are at risk of losing muscle strength. It will also explore whether this treatment can help slow down muscle…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   Mayo Clinic, Rochester, Minnesota

   Locations

   3 in total

   Run by

   Health Discovery Labs

   See if you can join NCT07362862 on ClinicalTrials.gov

7. Mental Effort During Low Load Resistance Training in Older Adults

   The goal of this clinical trial is to determine the effect of maximal mental effort combined with low-intensity resistance training on strength and neuromuscular function in older adults. The main questions it aims to answer are: * Does low-intensity resistance training in combination with maximal …

   Stage

   Not phased

   Ages

   65 to 85

   Site

   Kennesaw State University, Kennesaw, Georgia

   Run by

   Kennesaw State University

   See if you can join NCT07687316 on ClinicalTrials.gov

8. Strength Training and Resveratrol

   The main goal of this study is to find out if supplementing with resveratrol improves skeletal muscle adaptations to strengthening exercise (resistance training or strength training) in adults age 60+, and to determine whether circulating vehicles of inter-organ communication (extracellular vesicle…

   Stage

   Not phased

   Ages

   60 and older

   Site

   Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, Texas

   Run by

   Texas Tech University

   See if you can join NCT06585865 on ClinicalTrials.gov

9. Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

   The purpose of this research study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research on chronic diseases, nutrition, and metabolism (the process by which a…

   Stage

   Not phased

   Ages

   18 to 100

   Site

   University of Missouri-Columbia, Columbia, Missouri

   Run by

   Bettina Mittendorfer

   See if you can join NCT07083557 on ClinicalTrials.gov

10. The Foods & Oil to Repair, Correct and Enhance Strength (FORCES) Study

    The proposed research is a parallel arm, randomized placebo-controlled clinical trial designed to assess changes in muscle strength, volume, fatigue resistance, and mobility in older adults after daily consumption of 12g of linoleic acid-rich oil.

    Stage

    Not phased

    Ages

    65 to 80

    Site

    The Ohio State University, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT06361511 on ClinicalTrials.gov

11. Health Promotion With Targeted Exercise Intervention for Decreasing Fall Risk and Inactivity in Aging Veterans With Obesity and Signs of Sarcopenia

    Falls are a major health risk for older Veterans, especially those with both obesity and low muscle mass or strength (sarcopenia), which together increase the chances of falling and losing independence. Many older Veterans have difficulty staying active and often lack information about how to safel…

    Stage

    Not phased

    Ages

    55 and older

    Site

    Baltimore VA Medical Center VA Maryland Health Care System, Baltimore, MD, Baltimore, Maryland

    Run by

    VA Office of Research and Development

    See if you can join NCT07206368 on ClinicalTrials.gov

12. The Influence of Movement Velocity Biofeedback on Muscle Activation and Self Perception in Older Adults With Sarcopenia

    The overall objective for this clinical trial is to provide evidence for internal and external cueing for physical therapists and other rehabilitation clinicians to optimize resistance training within rehabilitation for older adults. The main questions it aims to answer are: * What is the impact of…

    Stage

    Not phased

    Ages

    60 to 95

    Site

    Creighton University, Omaha, Nebraska

    Run by

    Creighton University

    See if you can join NCT06853275 on ClinicalTrials.gov

13. Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults

    During this pilot study, the investigators will examine the effects of whole-body electrical muscle stimulation exercise (WB-EMS Exercise) on motoneuronal activation in healthy adults, which typically decreases with age. The investigators will also test whether WB-EMS Exercise will improve measures…

    Stage

    Not phased

    Ages

    18 and older

    Site

    NextGen Precision Health Building, Clinical and Translational Science Unit, Columbia, Missouri

    Run by

    University of Missouri-Columbia

    See if you can join NCT06689618 on ClinicalTrials.gov

14. Identifying Modifiable PAtient Centered Therapeutics (IMPACT) Frailty

    Frailty, the decline in physical and cognitive reserves leading to vulnerability to stressors is increasingly being recognized as a public health concern. Although multiple measures exist that can identify frail patients, very little is known about how or when to intervene. Sarcopenia, or the degre…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative Medicine, Los Angeles, California

    Run by

    University of California, Los Angeles

    See if you can join NCT04717869 on ClinicalTrials.gov

15. Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

    This study will examine the association between low muscle mass (myopenia) at diagnosis and chemotherapy toxicity in older adults with newly diagnosed advanced colorectal cancer.

    Stage

    Not phased

    Ages

    60 and older

    Site

    Beebe South Coastal Health Campus, Millville, Delaware

    Locations

    146 in total

    Run by

    Wake Forest University Health Sciences

    See if you can join NCT03998202 on ClinicalTrials.gov

16. Implementation of a Sarcopenia Clinic to Diagnose and Treat Skeletal Muscle Loss Due to COPD

    Sarcopenia, or skeletal muscle loss, impacts up to 40% of COPD patients and is a major cause for morbidity and mortality. Despite the high clinical significance of sarcopenia in COPD, the diagnosis remains elusive because accurate measures of skeletal muscle are not tested during routine clinical c…

    Stage

    Not phased

    Ages

    40 and older

    Site

    Cleveland Clinic Foundation, Cleveland, Ohio

    Run by

    The Cleveland Clinic

    See if you can join NCT07059637 on ClinicalTrials.gov

17. Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment

    Mild Cognitive Impairment (MCI) in older adults is linked to muscle loss (sarcopenia) and can lead to dementia, with pain further impacting cognitive and physical performance. Tai Chi, a mind-body exercise, is recommended for managing MCI as it supports cognitive function, mood, and physical health…

    Stage

    Not phased

    Ages

    60 and older

    Site

    Ohio University, Athens, Ohio

    Run by

    Ohio University

    See if you can join NCT06828926 on ClinicalTrials.gov