Recurrent Head and Neck Squamous Cell Carcinoma Clinical Trials in Irvine, California

3 studies are recruiting for recurrent head and neck squamous cell carcinoma in Irvine, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

    This phase II trial compares the effectiveness of cemiplimab with CDX-1140 to cemiplimab without CDX-1140 prior to surgery in treating patients with stage III-IV head and neck cancer. Immunotherapy with monoclonal antibodies, such as cemiplimab, may help the body's immune system attack the cancer, …

    Stage
    Phase 2
    Ages
    18 and older
    Site
    UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine, California
    Locations
    11 in total
    Run by
    National Cancer Institute (NCI)

    See if you can join NCT06980038 on ClinicalTrials.gov

  2. Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

    This phase I trial tests the safety, side effects, and best dose of camonsertib in combination with stereotactic body radiation therapy in controlling disease in patients with head and neck squamous cell cancer that has come back after a period of improvement (recurrent) or that cannot be removed b…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    City of Hope at Irvine Lennar, Irvine, California
    Locations
    3 in total
    Run by
    National Cancer Institute (NCI)

    See if you can join NCT07156227 on ClinicalTrials.gov

  3. Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

    This phase II trial studies the effect of pembrolizumab alone compared to the usual approach (chemotherapy [cisplatin and carboplatin] plus radiation therapy) after surgery in treating patients with head and neck squamous cell carcinoma that has come back (recurrent) or patients with a second head …

    Stage
    Phase 2
    Ages
    18 to 79
    Site
    UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine, California
    Locations
    178 in total
    Run by
    National Cancer Institute (NCI)

    See if you can join NCT04671667 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.