Quality of Life Clinical Trials

44 studies are recruiting for quality of life in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

   The purpose of this study is to determine the changes in quality of life and degree of tremor for patients with essential tremor or Parkinsonian tremor who are treated by stereotactic radiosurgery (SRS). This is a questionnaire-based study. Please see Detailed Description below for more information.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Vanderbilt University Medical Center, Nashville, Tennessee

   Run by

   Vanderbilt University Medical Center

   See if you can join NCT01734122 on ClinicalTrials.gov

2. Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

   The investigators will conduct a 13,000-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Arkansas for Medical Sciences (UAMS), Little Rock, Arkansas

   Locations

   24 in total

   Run by

   Washington University School of Medicine

   See if you can join NCT05991453 on ClinicalTrials.gov

3. Empowering Monterey Bay Residents for Activated, Collaborative, and Equitable Care

   The purpose of the EMBRACE Study is to evaluate whether a facilitated intervention improves shared decision-making (SDM) and patient activation among low-income and minority individuals more than usual care only. The ultimate goal is to enhance SDM and patient activation in care.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Stanford University, Palo Alto, California

   Run by

   Stanford University

   See if you can join NCT07652359 on ClinicalTrials.gov

4. AI-Based Personalized Exercise Prescription Through Mobile Health on Physical Activity and Health Outcomes in Older Adults: A Feasibility Study

   The purpose of this research is to investigate the feasibility, acceptability, appropriateness, and preliminary efficacy of a wearable and artificial intelligence-driven mobile application-based exercise prescription grounded in self-determination theory (SDT) and behavioral change techniques (BCTs…

   Stage

   Not phased

   Ages

   65 and older

   Site

   Kinesiology, Recreation, and Sport Studies (865) 974-3340 krss@utk.edu, Knoxville, Tennessee

   Run by

   The University of Tennessee, Knoxville

   See if you can join NCT07768670 on ClinicalTrials.gov

5. Developing a Smartphone Application to Support Veteran Opioid Use Disorder Treatment

   Opioid Use Disorder (OUD) is a complex, chronic condition affecting nearly 70,000 Veterans who can experience significantly reduced quality of life (e.g., poorer social, occupational, and health-related functioning). VA clinics providing Medication treatment for OUD (MOUD); e.g., buprenorphine, met…

   Stage

   Not phased

   Ages

   18 and older

   Site

   VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven, Connecticut

   Run by

   VA Office of Research and Development

   See if you can join NCT06454903 on ClinicalTrials.gov

6. Pain Intervention With Needling: Pilot Of Integrated Neuromodulation Techniques

   The study will be conducted on site in Galveston, Texas, United States. Study-related assessments and procedures will be performed at the designated clinical study site by qualified study personnel in accordance with the study protocol and applicable regulatory requirements. The study's purpose is …

   Stage

   Not phased

   Ages

   18 to 65

   Site

   University of Texas Medical Branch, Galveston, Galveston, Texas

   Run by

   The University of Texas Medical Branch, Galveston

   See if you can join NCT07112404 on ClinicalTrials.gov

7. CAPABLE Transplant

   The purpose of this mixed methods study is to adapt CAPABLE as CAPABLE Transplant to accomplish two things: 1) To resolve barriers to being classified as active on the Kidney Transplant (KT) waitlist, 2) as a surgical prehabilitation intervention targeting the pre-frail/ frail KT waitlist populatio…

   Stage

   Not phased

   Ages

   18 to 99

   Site

   Johns Hopkins School of Nursing, Baltimore, Maryland

   Run by

   Johns Hopkins University

   See if you can join NCT06326905 on ClinicalTrials.gov

8. Symptom Management and Survivorship Plus Coaching for Advanced Cancer Survivors and Their Caregivers

   The protocol will include a 10-week Symptom Management and Survivorship Handbook (SMSH) intervention to address informational needs for the management of physical and psychological symptoms, bundled with telephone delivered health coaching to address their symptom interference with physical, psycho…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Arizona Cancer Center, Tucson, Arizona

   Run by

   University of Arizona

   See if you can join NCT07415564 on ClinicalTrials.gov

9. A Randomized Control Trial of Conversations Advancing Resilience and Empowerment (CARE) Intervention

   The investigators propose to implement and evaluate the effectiveness of the peer-led CARE Intervention designed to mitigate health differences among rural and low-income communities in Texas. This intervention leverages the expertise of Community Health Workers (CHWs) to empower rural and low-inco…

   Stage

   Not phased

   Ages

   18 to 49

   Site

   The University of Texas at Rio Grande Valley, Edinburg, Texas

   Locations

   2 in total

   Run by

   University of Texas Rio Grande Valley

   See if you can join NCT07698964 on ClinicalTrials.gov

10. Improving Behavioral Health for Caregivers and Children After Pediatric Injury

    Pediatric traumatic injury (PTI) is a public health priority, with more than 125,000 children experiencing injuries that require hospitalization each year. These children, and their caregivers, are affected in many ways that may affect quality of life, emotional and behavioral health, physical reco…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Children's Hospital Los Angeles, Los Angeles, California

    Locations

    4 in total

    Run by

    Medical University of South Carolina

    See if you can join NCT06856057 on ClinicalTrials.gov

11. Impact of Positive Airway Pressure Therapy on Clinical Outcomes in Older Veterans With Chronic Obstructive Pulmonary Disease and Comorbid Obstructive Sleep Apnea (Overlap Syndrome)

    Obstructive sleep apnea (OSA) and Chronic Obstructive Pulmonary Disease (COPD) are highly prevalent chronic respiratory diseases in the Veteran population. OSA co-occurring with COPD, known as Overlap Syndrome (OVS), is a complex chronic medical condition associated with grave consequences. OVS is …

    Stage

    Not phased

    Ages

    60 and older

    Site

    John D. Dingell VA Medical Center, Detroit, MI, Detroit, Michigan

    Run by

    VA Office of Research and Development

    See if you can join NCT04179981 on ClinicalTrials.gov

12. CAPABLE Care + Connect

    In this evaluation scale-up research project, the investigators seek to test an implementation of CAPABLE on the infrastructure of home-based primary care for individuals who may experience social isolation and/or loneliness. These two home-based care programs may improve each other and provide opp…

    Stage

    Not phased

    Ages

    50 and older

    Site

    Johns Hopkins School of Nursing, Baltimore, Maryland

    Run by

    Johns Hopkins University

    See if you can join NCT07123298 on ClinicalTrials.gov

13. Exploring Virtual Reality Adventure Training Exergaming

    The current project aims to design and implement an 8-week Virtual Reality Adventure Therapy Exergaming (V-RATE) intervention focused on women veterans. A randomized controlled trial using a repeated measure design with a 1-month follow-up assessment will be employed to examine effects on physical …

    Stage

    Not phased

    Ages

    18 to 45

    Site

    University of Texas at Arlington, Arlington, Texas

    Run by

    The University of Texas at Arlington

    See if you can join NCT05563805 on ClinicalTrials.gov

14. Assessing the Effectiveness of Digital Wellness Modules on Perceived Quality of Life

    The study will examine the role of digital wellness modules (brief mindfulness and light to moderate physical exercise) delivered through a smartphone wellness application and their short-term effects on health behavior motivation and change, and longer-term quality of life and non-pathological aff…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Yale University, New Haven, Connecticut

    Run by

    Yale University

    See if you can join NCT05810259 on ClinicalTrials.gov

15. Compare Adjuvant Monotherapy With Endocrine or Accelerated Partial Breast Irradiation After Lumpectomy

    The aim of this prospective study is to investigate quality of life and oncologic outcomes in low-risk elderly breast cancer patients randomized to adjuvant therapy with accelerated partial breast irradiation (APBI) alone or endocrine therapy alone after lumpectomy. The study population will includ…

    Stage

    Phase 2

    Ages

    65 and older

    Site

    University of North Carolina, Chapel Hill, North Carolina

    Run by

    UNC Lineberger Comprehensive Cancer Center

    See if you can join NCT05472792 on ClinicalTrials.gov

16. Telehealth to Improve Quality of Life in Persons Living in Rural Texas

    The overarching goal of this project is to evaluate a current evidence-based practice, Cognitive Behavioral Therapy, for mental health conditions against Cognitive Behavioral Therapy plus two check-in calls a week for adults living in rural Texas.

    Stage

    Not phased

    Ages

    18 to 110

    Site

    Garrison Institute on Aging, Lubbock, Texas

    Run by

    Texas Tech University

    See if you can join NCT07119710 on ClinicalTrials.gov

17. Effect of a Fermented Dairy Protein With Prebiotic Fiber on GI Complaints

    A positive impact of a fermented dairy protein with prebiotic fiber supplement on self-reported GI complaints and wellbeing has been suggested (Wardenaar et al. 2024). The following project aims to further investigate the impact of this supplements in athletes with and without GI complaints in two …

    Stage

    Not phased

    Ages

    18 to 50

    Site

    ASU Health Futures Center, Phoenix, Arizona

    Run by

    Arizona State University

    See if you can join NCT06946017 on ClinicalTrials.gov

18. Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease

    The current study seeks to build on previous research that demonstrates the efficacy of Acceptance and Commitment Therapy in combating stigma by investigating the feasibility and acceptability of a protocol to support Black adolescents and young adults in coping with race related stress. The study …

    Stage

    Phase 1

    Ages

    14 to 21

    Site

    Children's Hospital Los Angeles, Los Angeles, California

    Run by

    Children's Hospital Los Angeles

    See if you can join NCT05685368 on ClinicalTrials.gov

19. Effect of Drain Care on Infection Rate and Quality of Life in Implant-Based Breast Reconstruction.

    The goal of this clinical trial is to learn whether showering with surgical drain tubes in place after first stage breast reconstruction causes increased risk of infection. The main questions it aims to answer are: * Is there an increased risk of infection/complications with showering 48 hours afte…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    University of Missouri, Columbia, Missouri

    Run by

    University of Missouri-Columbia

    See if you can join NCT05846438 on ClinicalTrials.gov

20. Enjoying Affordable and Tasty Food Together

    The goal of this pilot study is to examine the feasibility of a novel meal kit and nutrition education intervention among adults aged 40 years and older, who are lower income, and to evaluate the preliminary impact of the meal kit and nutrition education intervention on food insecurity, dietary qua…

    Stage

    Not phased

    Ages

    40 and older

    Site

    University of Massachusetts Lowell, Lowell, Massachusetts

    Run by

    University of Massachusetts, Lowell

    See if you can join NCT07036757 on ClinicalTrials.gov

21. The RolE of Prolonged Nightly faSTing to Improve Sleep and cOgnition in bREast Cancer Survivors

    The investigators are interested in finding out how Prolonged Nightly Fasting (PNF) and/or health education may impact health and cancer recovery for breast cancer patients and survivors.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Arizona State University, Phoenix, Arizona

    Run by

    Arizona State University

    See if you can join NCT06938555 on ClinicalTrials.gov

22. rTMS for Postoperative Brain Tumor Patients

    When doctors perform surgery to remove brain tumors, the goal is to take out as much of the tumor as possible while keeping the patient's brain functions intact. However, sometimes patients have trouble with movements like walking or using their hands after surgery. One reason for this is unintenti…

    Stage

    Not phased

    Ages

    22 to 65

    Site

    Columbia University Irving Medical Center, New York, New York

    Run by

    Brian J.Gill

    See if you can join NCT07530536 on ClinicalTrials.gov

23. OPtimizing Technology to Improve Medication Adherence and BP Control (OPTIMA-BP)

    Hypertension (HTN) has a greater impact on African Americans (AA) than any other U.S. racial group. Uncontrolled blood pressure (BP) contributes to higher rates of disability, death, and health resource use among AA. HTN is the single most influential risk factor for cardiovascular disease (CVD), a…

    Stage

    Not phased

    Ages

    50 and older

    Site

    Case Western Reserve University, Cleveland, Ohio

    Run by

    Case Western Reserve University

    See if you can join NCT05293756 on ClinicalTrials.gov

24. Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O)

    This study will enroll 120 women living with ovarian cancer following completion of initial treatment. Our objective is to test an intervention designed to provide support during the survivorship transition for this population, who live with a high degree of morbidity related to the illness and its…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Dan L Duncan Comprehensive Cancer Center at the O'Quinn Medical Tower at Baylor St. Luke's Medical Center, Houston, Texas

    Locations

    3 in total

    Run by

    Baylor College of Medicine

    See if you can join NCT05752448 on ClinicalTrials.gov

25. Pain in Aging Former Athletes, Master's Athletes, and Nonathletes

    The goal of this clinical trial is to determine how male and female former athletes experience pain and respond to moderate-intensity exercise (strength versus aerobic) compared with both current master's athletes and nonathletes. The main questions this study aims to address are: 1. How do former …

    Stage

    Not phased

    Ages

    35 to 65

    Site

    Marquette University, Milwaukee, Wisconsin

    Run by

    Marquette University

    See if you can join NCT07502742 on ClinicalTrials.gov