Pulmonary Arterial Hypertension Clinical Trials in Los Angeles, California

5 studies are recruiting for pulmonary arterial hypertension in Los Angeles, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)

   The primary objective of this study is to evaluate the effect of 24-weeks of once daily treatment with TPIP compared with placebo on exercise capacity in adults with PAH.

   Stage

   Phase 3

   Ages

   18 to 75

   Site

   USA012, Los Angeles, California

   Locations

   26 in total

   Run by

   Insmed Incorporated

   See if you can join NCT07481981 on ClinicalTrials.gov

2. Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

   The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK…

   Stage

   Not phased

   Ages

   0 to 20

   Site

   University of California, Los Angeles Medical Center, Los Angeles, California

   Locations

   52 in total

   Run by

   Duke University

   See if you can join NCT04278404 on ClinicalTrials.gov

3. Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

   This open-label extension study will evaluate the long-term safety, tolerability and efficacy of orally inhaled seralutinib in subjects who have completed a previous seralutinib study

   Stage

   Phase 3

   Ages

   18 to 75

   Site

   Department of Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California

   Locations

   120 in total

   Run by

   Gossamer Bio USA, Inc.

   See if you can join NCT06274801 on ClinicalTrials.gov

4. Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)

   The primary objectives of the study are to evaluate the safety and tolerability, and pharmacokinetics (PK) of sotatercept over 24 weeks of treatment in children ≥1 to <18 years of age with PAH World Health Organization (WHO) Group 1 on standard of care (SoC). There is no formal hypothesis.

   Stage

   Phase 2

   Ages

   1 to 17

   Site

   The Regents of the University of California - Los Angeles (UCLA Pediatrics) ( Site 1606), Los Angeles, California

   Locations

   35 in total

   Run by

   Merck Sharp & Dohme LLC

   See if you can join NCT05587712 on ClinicalTrials.gov

5. Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System

   This prospective study is a multi-center early feasibility study assessing the safety and performance of the Aria CV Pulmonary Hypertension System in patients with pulmonary hypertension and right heart dysfunction.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California-Los Angeles, Los Angeles, California

   Locations

   12 in total

   Run by

   Aria CV, Inc

   See if you can join NCT04555161 on ClinicalTrials.gov