Pulmonary Arterial Hypertension Clinical Trials in Cincinnati, Ohio

8 studies are recruiting for pulmonary arterial hypertension in Cincinnati, Ohio right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

   Researchers are looking for more ways to treat PAH. In PAH, the blood vessels in the lungs become thick and narrow, which makes it harder for blood to flow. This causes high blood pressure in the lungs and overworks the heart. PAH can make it hard to breathe and be active. Some standard (usual) tre…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   The Carl and Edyth Lindner Center for Research and Education at the Christ Hospital ( Site 1001), Cincinnati, Ohio

   Locations

   136 in total

   Run by

   Merck Sharp & Dohme LLC

   See if you can join NCT07218029 on ClinicalTrials.gov

2. An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)

   This is an adaptive, 2-part, randomized, multicenter, double-blind, placebo-controlled, parallel-group study designed to evaluate the efficacy and safety of IKT-001 in adult participants with WHO Group 1 PAH.

   Stage

   Phase 3

   Ages

   18 to 75

   Site

   University of Cincinnati, Cincinnati, Ohio

   Locations

   43 in total

   Run by

   Inhibikase Therapeutics

   See if you can join NCT07365332 on ClinicalTrials.gov

3. Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

   The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK…

   Stage

   Not phased

   Ages

   0 to 20

   Site

   Cincinnati Childrens Hospital Medical Center, Cincinnati, Ohio

   Locations

   52 in total

   Run by

   Duke University

   See if you can join NCT04278404 on ClinicalTrials.gov

4. Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

   This open-label extension study will evaluate the long-term safety, tolerability and efficacy of orally inhaled seralutinib in subjects who have completed a previous seralutinib study

   Stage

   Phase 3

   Ages

   18 to 75

   Site

   University of Cincinnati Medical Center, Cincinnati, Ohio

   Locations

   120 in total

   Run by

   Gossamer Bio USA, Inc.

   See if you can join NCT06274801 on ClinicalTrials.gov

5. Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)

   The primary objectives of the study are to evaluate the safety and tolerability, and pharmacokinetics (PK) of sotatercept over 24 weeks of treatment in children ≥1 to <18 years of age with PAH World Health Organization (WHO) Group 1 on standard of care (SoC). There is no formal hypothesis.

   Stage

   Phase 2

   Ages

   1 to 17

   Site

   Cincinnati Children's Hospital Medical Center ( Site 1602), Cincinnati, Ohio

   Locations

   35 in total

   Run by

   Merck Sharp & Dohme LLC

   See if you can join NCT05587712 on ClinicalTrials.gov

6. Pulmonary Hypertension Association Registry

   The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary Hypertension Care C…

   Stage

   Not phased

   Ages

   0 and older

   Site

   Cincinnati Children's Hospital, Cincinnati, Ohio

   Locations

   52 in total

   Run by

   Pulmonary Hypertension Association, Inc.

   See if you can join NCT04071327 on ClinicalTrials.gov

7. Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System

   This prospective study is a multi-center early feasibility study assessing the safety and performance of the Aria CV Pulmonary Hypertension System in patients with pulmonary hypertension and right heart dysfunction.

   Stage

   Not phased

   Ages

   18 and older

   Site

   The Christ Hospital, Cincinnati, Ohio

   Locations

   12 in total

   Run by

   Aria CV, Inc

   See if you can join NCT04555161 on ClinicalTrials.gov

8. Pediatric Pulmonary Hypertension Network (PPHNet) Informatics Registry

   Patients are being asked to be in this research study because medical researchers hope that by gathering information about a large number of children with pulmonary hypertension over time, their understanding of the disease process will increase and lead to better treatment. Investigators believe t…

   Stage

   Not phased

   Ages

   0 to 21

   Site

   Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

   Locations

   14 in total

   Run by

   New York Medical College

   See if you can join NCT02249923 on ClinicalTrials.gov