PTSD - Post Traumatic Stress Disorder Clinical Trials

17 studies are recruiting for ptsd - post traumatic stress disorder in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Targeted Plasticity Therapy for PTSD

   Objectives of this study are to provide continued safety assessment for the ReStore system, and to gain further estimates of the effect size of Vagus Nerve Stimulation (VNS) therapy with Prolonged Exposure Therapy (PE) compared to PE with placebo (sham) stimulation in participants with posttraumati…

   Stage

   Not phased

   Ages

   22 to 79

   Site

   The University of Texas Health Austin Ambulatory Surgery Center, Austin, Texas

   Locations

   3 in total

   Run by

   The University of Texas at Dallas

   See if you can join NCT06266364 on ClinicalTrials.gov

2. Redefine Study: A Study Evaluating the Efficacy, Safety, and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

   The Redefine Study (COMP202) is testing COMP360 to see if it may reduce post-traumatic stress disorder (PTSD) symptoms when administered alongside monitoring and support from a trained study team. COMP360 is a lab-made form of the naturally occurring chemical compound psilocybin.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Florida, Orlando, Florida

   Locations

   2 in total

   Run by

   COMPASS Pathways

   See if you can join NCT07570654 on ClinicalTrials.gov

3. Advancing Skills Through Consultation, Education, and Novel Technologies

   This research study tests strategies to train behavioral health providers in Written Exposure Therapy (WET), an evidence-based treatment for posttraumatic stress disorder (PTSD). There are a number of evidence-based treatments for posttraumatic stress disorder (PTSD). However, most behavioral healt…

   Stage

   Not phased

   Ages

   Any age

   Site

   University of Texas Health Science Center at San Antonio, San Antonio, Texas

   Run by

   The University of Texas Health Science Center at San Antonio

   See if you can join NCT07707102 on ClinicalTrials.gov

4. Accelerated Transcranial Magnetic Stimulation for Post-Traumatic Stress Disorder

   This study tests a new brain stimulation treatment for post-traumatic stress disorder (PTSD), a condition that affects millions after trauma, causing symptoms like flashbacks, avoidance, mood changes, and heightened alertness. The investigators will enroll 15 adults (ages 18-65) with PTSD. First, p…

   Stage

   Not phased

   Ages

   18 to 65

   Site

   Cognitive FX TMS Clinic, Provo, Utah

   Run by

   Cognitive FX

   See if you can join NCT07463703 on ClinicalTrials.gov

5. The New Empowerment After eXposure to Trauma (NEXT) Study

   The NEXT Study is a randomized controlled pilot examining the feasibility and acceptability of a revised perinatal PTSD protocol. This study will randomize perinatal participants with PTSD to receive NET (n=45); treatment group) and will be compared to perinatal women randomized to usual care (n=45…

   Stage

   Not phased

   Ages

   18 to 50

   Site

   Indiana University School of Medicine, Indianapolis, Indiana

   Run by

   Indiana University

   See if you can join NCT07175025 on ClinicalTrials.gov

6. Transcranial Magnetic Stimulation in Veterans With PTSD

   With this research investigators hope to begin to understand how rTMS can improve posttraumatic stress disorder (PTSD) symptoms. TMS improves PTSD through two interrelated mechanisms: change in brain limbic system function and change in systemic inflammatory activation. Participants who decide to j…

   Stage

   Not phased

   Ages

   19 to 70

   Site

   White River Junction VA Hospital, White River Junction, Vermont

   Run by

   White River Junction Veterans Affairs Medical Center

   See if you can join NCT07336251 on ClinicalTrials.gov

7. REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

   The goal of the REVEAL PTSD study is to test how well the Senseye DT works as a diagnostic test for Post-traumatic Stress Disorder (PTSD) in adults 18 and older who are experiencing one or more symptoms that might be related to PTSD. The Senseye DT is software as a medical device (SaMD) and is an i…

   Stage

   Phase 3

   Ages

   18 and older

   Site

   University of Colorado Anschutz Medical Campus, Aurora, Colorado

   Locations

   6 in total

   Run by

   Senseye, Inc.

   See if you can join NCT07280065 on ClinicalTrials.gov

8. Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD)

   The goal of this clinical trial is to evaluate the safety and effectiveness of the gammaCore non-invasive vagus nerve stimulation (nVNS) device as an additional treatment for symptoms of post-traumatic stress disorder (PTSD) in adults. The vagus nerve connects the brain with many organs and systems…

   Stage

   Not phased

   Ages

   18 to 70

   Site

   Acacia Research Center, Sunnyvale, California

   Run by

   Acacia Clinics

   See if you can join NCT07523685 on ClinicalTrials.gov

9. Trial of Acceptance and Mindfulness-based Exposure Therapy (AMBET) and Present Centered Therapy (PCT)

   The goal of this clinical trial is to learn if a new therapy called Acceptance- and Mindfulness-Based Exposure Therapy (AMBET) helps treat post-traumatic stress disorder (PTSD) in people who survived a cardiac arrest. This study will compare AMBET to another psychotherapy treatment called Present C…

   Stage

   Not phased

   Ages

   18 to 81

   Site

   Columbia University Irving Medical Center, New York, New York

   Run by

   Columbia University

   See if you can join NCT07410481 on ClinicalTrials.gov

10. A Frequency-Modulated Music Intervention to Enhance Cognitive Processing Therapy (CPT) for PTSD

    The goal of this clinical trial is to learn if the addition of frequency filtered music (Safe and Sound Protocol) to daily cognitive processing therapy improves effectiveness for reducing PTSD symptoms. The main questions it aims to answer are: * Does the addition of frequency filtered music reduce…

    Stage

    Not phased

    Ages

    18 and older

    Site

    The Ohio State University, Columbus, Ohio

    Locations

    2 in total

    Run by

    Ohio State University

    See if you can join NCT06925867 on ClinicalTrials.gov

11. Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

    The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related neuroinflammatory conditions. Participants in the United States aged 2 years…

    Stage

    Not phased

    Ages

    2 and older

    Site

    Brain Inflammation Collaborative, Delafield, Wisconsin

    Run by

    Brain Inflammation Collaborative

    See if you can join NCT04806620 on ClinicalTrials.gov

12. Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons

    Addiction and trauma exposure are common among the 5.5 million people (1 in 47 adults) in the U.S. who are in prison or under supervision. About 85% of people in prison have a substance use disorder or are there for a drug-related crime, and many have experienced serious trauma before being incarce…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Northeast Arkansas Community Corrections Center (NEACC), Osceola, Arkansas

    Locations

    6 in total

    Run by

    University of Arkansas

    See if you can join NCT06923423 on ClinicalTrials.gov

13. Accelerated Treatment for Co-occurring Insomnia, Nightmares, and PTSD

    This study is a two-arm individually randomized group treatment clinical trial evaluating behavioral therapies for insomnia, nightmares, and PTSD. The study will compare cognitive-behavioral therapy for insomnia and nightmares to sleep hygiene (Control), both integrated with Written Exposure Therap…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Fort Hood, Kileen, Texas

    Run by

    Palo Alto Veterans Institute for Research

    See if you can join NCT07069517 on ClinicalTrials.gov

14. Evaluating Evidenced Based Options for PTSD Treatment

    This study will look at: How practical it is to offer another round of proven therapy. How effective different therapy options are for people who didn't respond to the first treatment. The goal is to improve personalized care by: Identifying factors that might predict how someone will respond to a …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Rush University Medical Center, Chicago, Illinois

    Run by

    Rush University Medical Center

    See if you can join NCT06733376 on ClinicalTrials.gov

15. Veterans' Cognitive Function, Mental Health, and Quality of Life After Hyperbaric Oxygen Therapy

    The purpose of this study is to evaluate how hyperbaric oxygen therapy (HBOT) may affect cognitive functioning, post-traumatic stress disorder (PTSD), depression, anxiety, and overall quality of life in veterans. 1. Does Hyperbaric Oxygen Therapy improve cognitive functioning, psychological well-be…

    Stage

    Phase 2

    Ages

    18 to 75

    Site

    Summit Hyperbarics and Wellness, Boise, Idaho

    Run by

    Summit Hyperbarics and Wellness

    See if you can join NCT07214415 on ClinicalTrials.gov

16. Treatment for PTSD and Tinnitus

    In this study, researchers are examining the best sequence of interventions for posttraumatic stress disorder (PTSD) and tinnitus. Participants will either receive psychotherapy for PTSD first (Cognitive Processing Therapy; CPT), followed by treatment for tinnitus (Cognitive Behavioral Therapy for …

    Stage

    Not phased

    Ages

    18 and older

    Site

    The University of Texas Health Science Center at San Antonio, San Antonio, Texas

    Run by

    The University of Texas Health Science Center at San Antonio

    See if you can join NCT07106593 on ClinicalTrials.gov

17. Restorative Early Sleep Treatment After the Emergency Department

    The goal of this randomized controlled trial is to pilot the virtual delivery of cognitive behavioral therapy for insomnia (CBT-I) and nightmares (CBT-I\&N) via telehealth as an early intervention for treating posttraumatic sleep disturbance in acute trauma patients exposed to interpersonal violenc…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Henry Ford Hospital System, Detroit, Michigan

    Run by

    Henry Ford Health System

    See if you can join NCT07121270 on ClinicalTrials.gov