Psoriasis Clinical Trials

29 studies are recruiting for psoriasis in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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East Windsor, New Jersey 6 Waltham, Massachusetts 4 Birmingham, Alabama 3 Fountain Valley, California 3 Houston, Texas 3 New York, New York 3 Philadelphia, Pennsylvania 3

Studies now recruiting

  1. Metabolic Profiling of Immune Responses in Immune-mediated Diseases

    Background: The immune system is the part of the body that fights infection. Some people have immune deficiencies that cause skin rashes, make them get sick often with infections, or make it difficult for their skin to heal. Researchers want to learn more to better treat conditions that affect immu…

    Stage
    Not phased
    Ages
    18 to 75
    Site
    National Institutes of Health Clinical Center, Bethesda, Maryland
    Run by
    National Institute of Allergy and Infectious Diseases (NIAID)

    See if you can join NCT04864886 on ClinicalTrials.gov

  2. Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

    This phase Ib trial studies the side effects of nivolumab and to see how well it works alone and in combination with other treatments, such as ipilimumab, cabozantinib, platinum containing therapy, and fluoropyrimidine, in treating patients with autoimmune disorders and cancer that has spread from …

    Stage
    Phase 1
    Ages
    18 and older
    Site
    University of California Davis Comprehensive Cancer Center, Sacramento, California
    Locations
    52 in total
    Run by
    National Cancer Institute (NCI)

    See if you can join NCT03816345 on ClinicalTrials.gov

  3. The Impact of Salt Intake on Sodium in the Skin and Inflammatory Skin Disease

    The goal of this clinical trial is to demonstrate the feasibility of a trial that examines the impact of changes in dietary sodium intake on skin sodium levels, atopic dermatitis, and psoriasis. In addition, it aims to generate preliminary data to begin to answer the following questions: 1. Is ther…

    Stage
    Phase 4
    Ages
    18 and older
    Site
    UCSF Mt Zion Campus, San Francisco, California
    Locations
    2 in total
    Run by
    University of California, San Francisco

    See if you can join NCT07487831 on ClinicalTrials.gov

  4. Mediterranean Diet vs no Dietary Intervention for Improving Signs and Symptoms of Psoriasis in Patients Treated With Anti-IL-17 or Anti-IL-23 Inhibitors

    In this study, participants will have 3 or 4 total study visits over approximately 10 total weeks. There is a two week medication washout period in between the 1st and 2nd visits. This washout only applies if participants are using a prohibited psoriasis medication (such as topical steroids or oral…

    Stage
    Not phased
    Ages
    18 to 94
    Site
    University Hospitals Cleveland Medical Center, Cleveland, Ohio
    Run by
    University Hospitals Cleveland Medical Center

    See if you can join NCT06399432 on ClinicalTrials.gov

  5. A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

    The main purpose of this study is to assess the effectiveness of adding tirzepatide to ixekizumab therapy in standard clinical practice in participants with moderate-to-severe plaque PsO and obesity or overweight with at least 1 weight-related comorbidity. The study will last up to 12 months.

    Stage
    Phase 4
    Ages
    18 and older
    Site
    Medical Dermatology Specialists, Phoenix, Arizona
    Locations
    39 in total
    Run by
    Eli Lilly and Company

    See if you can join NCT06857942 on ClinicalTrials.gov

  6. A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically

    The purpose of this post-marketing study is to assess the amount of guselkumab in breast milk of lactating women receiving guselkumab as part of their standard clinical care provided by their treating physician, for any of the approved indications.

    Stage
    Phase 4
    Ages
    18 and older
    Site
    University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
    Run by
    Janssen Research & Development, LLC

    See if you can join NCT07654751 on ClinicalTrials.gov

  7. The CorEvitas Psoriasis (PSO) Registry

    The primary objective of the CorEvitas Psoriasis Registry is to study the comparative safety of approved psoriasis therapies in a North American cohort of psoriasis subjects treated by dermatologists. This includes assessing the incidence and nature of adverse events of special interest, including …

    Stage
    Not phased
    Ages
    18 and older
    Site
    Research site, Waltham, Massachusetts
    Run by
    CorEvitas

    See if you can join NCT02707341 on ClinicalTrials.gov

  8. PPD™ CorEvitas™ Psoriasis (PSO) Rapid Response Non-Interventional Study

    This is a 16-week prospective, single-arm cohort, study of patients initiating advanced therapy for the treatment of moderate-to-severe plaque PSO. Eligible patients must be willing to be seen in-person by their treating physician for a Baseline visit (with first dose of the advanced therapy occurr…

    Stage
    Not phased
    Ages
    18 and older
    Site
    CorEvitas, LLC, Waltham, Massachusetts
    Run by
    CorEvitas

    See if you can join NCT07615712 on ClinicalTrials.gov

  9. PPD™ CorEvitas™ Psoriasis (PSO) Early Treatment Response Non-Interventional Study

    This is a 24-week prospective, single-arm cohort, study of patients initiating advanced therapy for the treatment of moderate-to-severe plaque PSO. Eligible patients must be willing to be seen in-person by their treating physician for a Baseline visit (with first dose of the advanced therapy occurr…

    Stage
    Not phased
    Ages
    18 and older
    Site
    CorEvitas, LLC, Waltham, Massachusetts
    Run by
    CorEvitas

    See if you can join NCT07648602 on ClinicalTrials.gov

  10. Skin Microbial Ecology in Atopic Dermatitis

    Everybody's skin has bacteria that normally lives on it. Previous research has shown that people with eczema (or atopic dermatitis [AD]) have much higher concentrations of a certain bacteria (S. aureus), especially when their disease is active but little is known about the role that this bacteria p…

    Stage
    Not phased
    Ages
    13 and older
    Site
    University of Rochester Medical Center, Rochester, New York
    Run by
    University of Rochester

    See if you can join NCT04170244 on ClinicalTrials.gov

  11. A Study to Evaluate D-2570 in Participants With Moderate to Severe Plaque Psoriasis

    A Study looking at the safety and efficacy of D-2570 in Participants with Plaque Psoriasis

    Stage
    Phase 2
    Ages
    18 to 70
    Site
    Study Center, Birmingham, Alabama
    Locations
    20 in total
    Run by
    InventisBio Co., Ltd

    See if you can join NCT07489885 on ClinicalTrials.gov

  12. Use of Total-Body PET to Quantify Systemic and Cutaneous Inflammation in Psoriasis Patients Before and After Intervention With a Nutritionally Balanced Diet

    Psoriasis is a chronic inflammatory disease that affects the skin and joints in 2-3 % of people in the United States. This inflammation of the skin, joints, and blood vessels in patients with psoriasis has been measured by older PET Scan technology but with limitations. With the new EXPLORER PET sc…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of California, Davis - Dermatology Department, Sacramento, California
    Run by
    University of California, Davis

    See if you can join NCT06574178 on ClinicalTrials.gov

  13. Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

    This study learn how easily patients can use an educational tool that will be created for patients with melanoma and pre-existing autoimmune diseases who receive or will receive immune checkpoint inhibitor drugs. Patients will be asked their opinions about the design, accessibility, and content of …

    Stage
    Not phased
    Ages
    18 and older
    Site
    M D Anderson Cancer Center, Houston, Texas
    Run by
    M.D. Anderson Cancer Center

    See if you can join NCT04751396 on ClinicalTrials.gov

  14. Regulation of Inflammatory Genes in Psoriasis

    Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory changes in the skin. An extensive cytokine network including generated by activated dendritic cells and T cells mediates the formation of psoriatic lesions. These immune-response parameters can be used as marker…

    Stage
    Not phased
    Ages
    19 to 99
    Site
    The Kirklin Clinic, Birmingham, Alabama
    Run by
    University of Alabama at Birmingham

    See if you can join NCT03125655 on ClinicalTrials.gov

  15. Development of Predictive Psoriasis Response Endotypes Using Single Cell Transcriptomics

    The investigators propose to improve the possibility of reaching skin resolution by identifying certain markers or gene patterns that may predict patient response to certain psoriasis drugs ahead of time, thus eliminating or reducing the trial-and-error approach often employed. The ability to rule …

    Stage
    Phase 4
    Ages
    18 to 89
    Site
    University Hospitals Cleveland Medical Center, Cleveland, Ohio
    Run by
    University Hospitals Cleveland Medical Center

    See if you can join NCT05270733 on ClinicalTrials.gov

  16. Multi-Center PAMPA Study

    This is a multi-center (North-America), randomized, double-blind, placebo-controlled, wait-list, interventional, preventive trial of guselkumab in high-risk psoriasis patients compared to non-biologic standard of care. The primary objective of the proposed trial will be to test the hypothesis that …

    Stage
    Phase 4
    Ages
    18 and older
    Site
    Brigham and Women's Hospital, Boston, Massachusetts
    Locations
    5 in total
    Run by
    NYU Langone Health

    See if you can join NCT05004727 on ClinicalTrials.gov

  17. A Study to Evaluate the Impact of a Magnolia Officinalis Dietary Supplement on Immune Biomarkers in Subjects With Psoriasis

    The goal of this clinical trial is to evaluate whether Viv, a consumer-grade dietary supplement derived from the Magnolia officinalis plant, has an effect on biomarkers of immune activity in adults with psoriasis. To address this question, this trial will compare Viv to a placebo (a look-alike subs…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Decentralized Study Coordinating Center, Englewood, New Jersey
    Run by
    Sirt3 LLC

    See if you can join NCT07471048 on ClinicalTrials.gov

  18. Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research

    The unhide® Project is a non-interventional, longitudinal research study designed to establish a secure data repository of demographic, health, and lifestyle information from individuals with brain inflammation and related neuroinflammatory conditions. Participants in the United States aged 2 years…

    Stage
    Not phased
    Ages
    2 and older
    Site
    Brain Inflammation Collaborative, Delafield, Wisconsin
    Run by
    Brain Inflammation Collaborative

    See if you can join NCT04806620 on ClinicalTrials.gov

  19. A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis

    This study is to evaluate the safety, the systemic exposure of halobetasol propionate (HP), and the hypothalamic-pituitary-adrenal (HPA) axis suppression potential for topically applied IDP-122 lotion in pediatric participants with moderate to severe plaque psoriasis.

    Stage
    Phase 4
    Ages
    6 to 17
    Site
    Bausch Site 2, Thousand Oaks, California
    Locations
    9 in total
    Run by
    Bausch Health Americas, Inc.

    See if you can join NCT03987763 on ClinicalTrials.gov

  20. Evaluate the Safety and Pharmacokinetics/Pharmacodynamics of HS-20118

    The study will be conducted in 2 parts (SAD for Part 1 and MAD for Part2). Part 1 is a single-center, randomized, double-blind, placebo-controlled, SAD study to evaluate the safety, tolerability, immunogenicity, and PK of HS-20118 after a single oral dose in healthy participants. Part 2 is a multi-…

    Stage
    Phase 1
    Ages
    18 to 65
    Site
    Pacific Clinical Research Network (PCRN), Auckland, Takapuna, Auckland
    Locations
    9 in total
    Run by
    Jiangsu Hansoh Pharmaceutical Co., Ltd.

    See if you can join NCT06846710 on ClinicalTrials.gov

  21. Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

    The purpose of the OTIS Autoimmune Diseases in Pregnancy Study is to monitor planned and unplanned pregnancies exposed to certain medications, to evaluate the possible teratogenic effect of these medications and to follow live born infants for one year after birth. With respect to fetal outcome, it…

    Stage
    Not phased
    Ages
    Any age
    Site
    University of California, San Diego, La Jolla, California
    Run by
    University of California, San Diego

    See if you can join NCT02103361 on ClinicalTrials.gov

  22. Study of SFA002 in Patients with Mild to Moderate Psoriasis Plaques

    The purpose of this study is to determine the safety, metabolism and potential effect of drug product SFA-002 on mild moderate and severe chronic plaque psoriasis. Psoriasis is a common chronic skin disorder that affects over 4 million people. There is no cure for psoriasis and treatment is directe…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    NuLine Clinical Trial Center, Pompano Beach, Florida
    Locations
    3 in total
    Run by
    SFA Therapeutics

    See if you can join NCT05642182 on ClinicalTrials.gov

  23. A Real-world Observational Study to Compare Effectiveness of Deucravacitinib Vs Apremilast in Adults With Plaque Psoriasis

    The purpose of this study is to understand the comparative effectiveness of deucravacitinib versus apremilast in adults with plaque psoriasis.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Local Institution, Waltham, Massachusetts
    Run by
    Bristol-Myers Squibb

    See if you can join NCT05744466 on ClinicalTrials.gov

  24. IMPACT - AndHealth Autoimmune Research Registry

    This is a patient research registry aimed at evaluating the effectiveness of a comprehensive, root-cause medical approach ("AndHealth program") for autoimmune disorders. This approach involves a combination of pharmacological and non-pharmacological therapies offered under the care of a licensed ph…

    Stage
    Not phased
    Ages
    18 to 70
    Site
    AndHealth, Columbus, Ohio
    Run by
    AndHealth

    See if you can join NCT05883371 on ClinicalTrials.gov

  25. Taltz in Combination With Enstilar for Psoriasis

    Enstilar in combination with Taltz for plaque psoriasis.

    Stage
    Phase 4
    Ages
    18 and older
    Site
    Psoriasis Treatment Center of Central New Jersey, East Windsor, New Jersey
    Run by
    Psoriasis Treatment Center of Central New Jersey

    See if you can join NCT04372277 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.