Premature Birth Clinical Trials

17 studies are recruiting for premature birth in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Madison, Wisconsin 4 Philadelphia, Pennsylvania 4

Studies now recruiting

  1. Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age

    Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and neurodevelopmental impairments (NDI) at significant rates, disproportionate to their term peers. Ea…

    Stage
    Not phased
    Ages
    0 to 6
    Site
    Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
    Run by
    Ann & Robert H Lurie Children's Hospital of Chicago

    See if you can join NCT05336890 on ClinicalTrials.gov

  2. Growing Little PEAPODS Study

    The goal of this clinical trial is to learn more about how the food and nutrition babies receive while in the Neonatal Intensive Care Unit (NICU) influences their ability to gain weight and fat-free mass, and their future growth and development. Participants will: * have body growth measurements co…

    Stage
    Not phased
    Ages
    0 to 0
    Site
    Meriter Hospital, Inc., Madison, Wisconsin
    Run by
    University of Wisconsin, Madison

    See if you can join NCT06226051 on ClinicalTrials.gov

  3. Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

    The goal of the Tiny Baby Collaborative Multicenter Inventory of Neonatal-Perinatal Interventions (MINI) minimum dataset is to serve as a registry detailing the outcomes and practices for all deliveries and infants admitted to intensive care at 22-23 weeks' gestation at participating hospitals.

    Stage
    Not phased
    Ages
    0 to 1
    Site
    University of Alabama at Birmingham, Birmingham, Alabama
    Locations
    59 in total
    Run by
    The University of Texas Health Science Center, Houston

    See if you can join NCT05685745 on ClinicalTrials.gov

  4. Pharmacokinetics and Placental Transfer of Caffeine

    The goal of this study is to learn how a pregnant person's body processes caffeine and how much caffeine crosses the placenta to the baby. A small dose of caffeine will be given to each pregnant participant before delivery. Blood will be drawn to measure caffeine levels in the pregnant mother. Bloo…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Riley Hospital for Children, Indianapolis, Indiana
    Run by
    Indiana University

    See if you can join NCT07570121 on ClinicalTrials.gov

  5. LATe Cerclage in High-risk Pregnancies (LATCH)

    The goal of this clinical trial is to determine whether cervical cerclage reduces the risk of preterm birth in patients with a short transvaginal ultrasound (TVU) cervical length (CL) ≤25mm between 24 0/7-26 6/7 weeks.

    Stage
    Not phased
    Ages
    18 to 50
    Site
    Atrium Health Carolinas Medical Center, Charlotte, North Carolina
    Locations
    2 in total
    Run by
    Thomas Jefferson University

    See if you can join NCT06036446 on ClinicalTrials.gov

  6. The Periviable GOALS Decision Support Tool

    The Periviable GOALS (Getting Optimal Alignment around Life Support) decision support tool (DST) is meant to facilitate informed shared decision-making regarding neonatal resuscitation for families facing the threat of a periviable delivery (deliveries occurring between 22 0/7 - 25 6/7 weeks gestat…

    Stage
    Not phased
    Ages
    18 and older
    Site
    The University of California San Diego, San Diego, California
    Locations
    12 in total
    Run by
    Indiana University

    See if you can join NCT05264779 on ClinicalTrials.gov

  7. Healing Tiny Minds: Rural Recovery Through Virtual and Lived Experience Care

    The goal of this behavioral-interventional study is to learn if the Abecedarian Approach implemented virtually for children ages 0-5 with a history of Hypoxic Ischaemic Encephalopathy (HIE) and/or premature birth produces the same effects as when administered at in-person facilities.

    Stage
    Not phased
    Ages
    Up to 5
    Site
    University of Wisconsin Madison, Madison, Wisconsin
    Run by
    University of Wisconsin, Madison

    See if you can join NCT06643598 on ClinicalTrials.gov

  8. PPROM Registry (Preterm Premature Rupture of Membranes)

    Preterm Premature Rupture of Membranes (PPROM) before 37 weeks of pregnancy is responsible for 40% of preterm births in the United States. The PPROM Registry aims to identify possible causes of PPROM, evaluate trends in expectant management, measure maternal and fetal care, and to review short term…

    Stage
    Not phased
    Ages
    14 to 55
    Site
    Www.Aapprom.Org/the-Registry, Denver, Colorado
    Run by
    American Alliance for pProm Support

    See if you can join NCT02997345 on ClinicalTrials.gov

  9. Biomarkers Study in Infants With Prior Neonatal Brain Injury

    This research focuses on the long-term cognitive development of children, including healthy infants and those who had a perinatal brain injury. As part of this research study, children complete in-person games and assessments at UW-Madison University Hospital. Children will also take part in an EEG…

    Stage
    Not phased
    Ages
    0 to 2
    Site
    University of Wisconsin Madison University Hospital, Madison, Wisconsin
    Run by
    University of Wisconsin, Madison

    See if you can join NCT07413900 on ClinicalTrials.gov

  10. taVNS-Paired Breastfeeding to Improve Breastfeeding at Discharge

    Investigators aim to improve the skills of premature or sick term infants in breastfeeding by boosting motor learning with transcutaneous vagus nerve stimulation. Investigators will recruit 10 premature, ≥ 35 weeks gestational age, or convalescing sick term infants admitted to the NICU at MUSC to p…

    Stage
    Not phased
    Ages
    0 and older
    Site
    Medical University of South Carolina Shawn Jenkins Children's Hospital, Charleston, South Carolina
    Run by
    Medical University of South Carolina

    See if you can join NCT06417385 on ClinicalTrials.gov

  11. Optimizing Family Counseling for Anticipated Extremely Preterm Delivery

    Antenatal family counseling for anticipated extremely preterm deliveries remains ethically and practically challenging for maternal-fetal medicine specialists and neonatologists alike. The overall goal of this project is to improve antenatal counseling and counseling outcomes for families facing an…

    Stage
    Not phased
    Ages
    18 to 99
    Site
    Boston Children's Hosptial, Boston, Massachusetts
    Locations
    3 in total
    Run by
    Boston Children's Hospital

    See if you can join NCT03819933 on ClinicalTrials.gov

  12. Postpartum Care in the NICU (PeliCaN) Transitions

    This is a randomized controlled trial of a dyad-centered, doula support and healthcare coordination model of care in a large urban neonatal intensive care unit (NICU), which serves a high-risk, low-income, majority Black population. In addition to doula support and coordination of care in the NICU,…

    Stage
    Not phased
    Ages
    16 and older
    Site
    Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
    Run by
    University of Pennsylvania

    See if you can join NCT06521398 on ClinicalTrials.gov

  13. Development of a Therapeutic Device to Improve Speech Sound Differentiation in Preterm Infants

    The goal of this clinical study is to test a new, novel medical device designed to improve speech sound differentiation among hospitalized preterm infants. The device is designed to be used at an age equivalent to 32 weeks of gestation or older and to integrate readily into clinical practice for us…

    Stage
    Not phased
    Ages
    0 to 0
    Site
    Emory University, Atlanta, Georgia
    Locations
    2 in total
    Run by
    Thrive Neuromedical, LLC

    See if you can join NCT06063122 on ClinicalTrials.gov

  14. Spinal Stimulation and Mobility Devices

    This research study will combine non-invasive spinal stimulation with mobility devices to examine the acute impact of the individual and combined effects of these innovative techniques on mobility in children with cerebral palsy.

    Stage
    Not phased
    Ages
    4 to 70
    Site
    University of Washington, Seattle, Washington
    Run by
    University of Washington

    See if you can join NCT05520359 on ClinicalTrials.gov

  15. Prophylactic Minimally Invasive Surfactant Evaluation

    The purpose of this study is to explore the question: Does prophylactic administration of exogenous surfactant in the delivery room, using a minimally-invasive technique, improve outcome in preterm infants 22-29 weeks' gestation compared to rescue treatment using the same technique?

    Stage
    Phase 4
    Ages
    Any age
    Site
    Northshore University Healthsystem, Evanston, Illinois
    Run by
    Endeavor Health

    See if you can join NCT06007547 on ClinicalTrials.gov

  16. A Randomized Control Trial of a Responsive Parenting Intervention to Support Healthy Brain Development and Self-regulation in Toddlers Born Preterm

    The purpose of this study is to determine whether participation in the Play and Learning Strategies (PALS) parenting intervention results in increased caregiver responsiveness behaviors and to test if participation in PALS results in increases in toddler skills and/or toddler neurological developme…

    Stage
    Not phased
    Ages
    1 to 2
    Site
    The University of Texas Health Science Center at Houston, Houston, Texas
    Run by
    The University of Texas Health Science Center, Houston

    See if you can join NCT04856501 on ClinicalTrials.gov

  17. A Randomized Controlled Trial of Impact of Wearable, Wireless Breast Pumps on Frequency and Efficacy of Milk Expression in Mothers of Premature Infants

    A randomized controlled trial of impact of wearable, wireless breast pumps on how often and how much milk mothers of premature infants can pump.

    Stage
    Not phased
    Ages
    Any age
    Site
    Ascension Seton Medical Center, Austin, Texas
    Run by
    University of Texas at Austin

    See if you can join NCT06723067 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.