Pregnancy Clinical Trials

83 studies are recruiting for pregnancy in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 3

1. CHIME: Comparing Health Interventions for Maternal Equity

   The goal of this comparative effectiveness trial is to compare how three different approaches to overcome barriers to resources and provide nutrition and physical activity counseling improve maternal healthy weight in pregnancy and postpartum. The main question it aims to answer is which of the two…

   Stage

   Not phased

   Ages

   18 and older

   Site

   New York Presbyterian Queens, Flushing, New York

   Locations

   4 in total

   Run by

   Stanford University

   See if you can join NCT06724172 on ClinicalTrials.gov

2. Feasibility of an ADAPTive Intervention to Improve Food Security and Maternal-Child Health

   Food insecurity affects up to 30% of pregnancies and leads to worse health in pregnant people and their children, including an increased risk of gestational diabetes, pre-term birth, and future cardiometabolic chronic conditions (e.g., type 2 diabetes and obesity). Interventions are being utilized …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Wake Forest University Health Sciences, Winston-Salem, North Carolina

   Run by

   Wake Forest University Health Sciences

   See if you can join NCT06942598 on ClinicalTrials.gov

3. Rhode Island Community-based Maternal Support Services

   The purpose of this project is to improve perinatal health outcomes in Rhode Island by bringing together the hospital, community health workers (CHWs), doulas, and community-based organizations to build a service delivery model that addresses care coordination and social determinants of health (SDO…

   Stage

   Not phased

   Ages

   Any age

   Site

   Brown University OBGYN, Providence, Rhode Island

   Locations

   7 in total

   Run by

   Women and Infants Hospital of Rhode Island

   See if you can join NCT07446374 on ClinicalTrials.gov

4. Mitigating Response to Stressors in Pregnant Women

   Stress-induced pregnancy complications are significant contributors to preterm labor as well as maternal and perinatal morbidity and mortality. The goals of this study are two folds: first it aims to capture the pregnant woman's journey to seek and receive prenatal care. Second, this study aims to …

   Stage

   Not phased

   Ages

   21 to 37

   Site

   Nova Southeastern University, Davie, Florida

   Run by

   Nova Southeastern University

   See if you can join NCT06718907 on ClinicalTrials.gov

5. Grocery Delivery and Healthy Weight Gain Among Low-income Pregnant Young Women

   This project will increase knowledge about how a simple intervention, grocery delivery, impacts weight gain and diet among low-income pregnant young women. Results can then be used to support other pregnant young women.

   Stage

   Not phased

   Ages

   14 to 26

   Site

   The University of Michigan, Ann Arbor, Michigan

   Run by

   University of Michigan

   See if you can join NCT05000645 on ClinicalTrials.gov

6. Hemophilia A Research Program

   This study longitudinally observes the intergenerational (mother-child) continuum in hemophilia A from pregnancy through early childhood. Because the study follows mother-child pairs, the study includes both a maternal cohort and a pediatric cohort. Each cohort has a primary goal: for the mother wi…

   Stage

   Not phased

   Ages

   Any age

   Site

   University of Washington, Seattle, Washington

   Run by

   University of Washington

   See if you can join NCT07414511 on ClinicalTrials.gov

7. Study of Placental Function in Healthy and Pathological Pregnancies

   The purpose of this study is to establish a tissue and data repository consisting of samples of human placentas, umbilical cord blood, and maternal blood, collected at the time of delivery. Specimens will be used in cellular, molecular, and functional studies to learn more about changes in placenta…

   Stage

   Not phased

   Ages

   18 to 45

   Site

   University of Colorado Hospital, Aurora, Colorado

   Run by

   University of Colorado, Denver

   See if you can join NCT02321007 on ClinicalTrials.gov

8. Effects of High Altitude on AMPK Activation

   Pregnancy elicits adaptive changes in uteroplacental blood flow, which are altered at high altitude and may contribute to the observed 3-fold increase in intrauterine growth restriction (IUGR) and preeclampsia (PreE). The investigators propose to collect myometrial, cord blood, and placental tissue…

   Stage

   Not phased

   Ages

   18 to 45

   Site

   University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado

   Run by

   University of Colorado, Denver

   See if you can join NCT02391519 on ClinicalTrials.gov

9. Perelel Prenatal Supplements vs. Generic Prenatal Supplements and Health of Mother and Baby (SUPPORT)

   The goal of this clinical trial is to learn if using Perelel-brand prenatal supplements versus a generic prenatal supplement improves the health of the mother and fetus (unborn baby) during pregnancy. The main question it aims to answer is: • How does taking Perelel prenatal supplements versus gene…

   Stage

   Not phased

   Ages

   14 and older

   Site

   UPMC Magee-Womens Hospital, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT07046845 on ClinicalTrials.gov

10. Ropivacaine and Fentanyl for Labor Epidural Initiation

    This study is being done to determine the most effective dose of medicine to use to initially provide effective pain relief within the first 30 minutes of receiving an epidural for pain labor during labor. The study team will also study any side effects related to the epidural medication and patien…

    Stage

    Phase 3

    Ages

    18 and older

    Site

    University of California, San Francisco, San Francisco, California

    Run by

    University of California, San Francisco

    See if you can join NCT07076368 on ClinicalTrials.gov

11. Avalglucosidase Alfa Pregnancy Study

    This is a worldwide, descriptive safety study collecting data on women and their offspring exposed to avalglucosidase alfa during pregnancy and/or lactation, to assess the risks of avalglucsodiase alfa on pregnancy and maternal complications and adverse effects in the developing fetus, neonate, and…

    Stage

    Not phased

    Ages

    Any age

    Site

    Investigational site worldwide, Bridgewater, New Jersey

    Run by

    Sanofi

    See if you can join NCT05734521 on ClinicalTrials.gov

12. Healthy Mom Zone Gestational Weight Gain Management Intervention 2.0

    The goal of this clinical trial is to see if the enhanced HMZ 2.0 intervention with new control system/digital platform to regulate gestational weight gain (GWG) and impact maternal-infant outcomes while collecting implementation data works and can be given to other pregnant women in various settin…

    Stage

    Not phased

    Ages

    18 to 45

    Site

    Pennsylvania State University, University Park, Pennsylvania

    Run by

    Penn State University

    See if you can join NCT05807594 on ClinicalTrials.gov

13. Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation

    The PLANET Study aims to determine the impact of microplastics on intestinal inflammation and gut microbiome in order to understand the role of this pollutant on the risk of developing inflammatory bowel disease (IBD) as well as other diseases. With this information, the researchers hope to charact…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Icahn School of Medicine at Mount Sinai, New York, New York

    Run by

    Icahn School of Medicine at Mount Sinai

    See if you can join NCT06001450 on ClinicalTrials.gov

14. UCLA Perinatal Biospecimen Repository

    The purpose of this investigator-initiated prospective observational cohort study is to establish the new UCLA Perinatal Biospecimen Repository (Perinatal Repository) for collection, storage, and distribution of the human data and biospecimens of the participants with perinatal pathology. The secur…

    Stage

    Not phased

    Ages

    Any age

    Site

    Afshar Lab, Department of Obstetrics & Gynecology, UCLA, Los Angeles, California

    Run by

    Yalda Afshar, MD, PhD

    See if you can join NCT05035160 on ClinicalTrials.gov

15. Prenatal Study in Healthy Pregnant Women

    Clinical Trial Summary The goal of this clinical trial is to address the impact of a gummy prenatal vs a capsule based prenatal in pregnant women. The main question it aims to answer is: Does 12-week daily administration of Prenatal Capsule affect serum iron levels in pregnant women in their second…

    Stage

    Not phased

    Ages

    21 to 40

    Site

    Atlantia Clinical Trials, Chicago, Chicago, Illinois

    Run by

    Perelel Inc.

    See if you can join NCT07226414 on ClinicalTrials.gov

16. Advanced Fetal Imaging - Phase II

    The goal of Advanced Fetal Imaging - Phase II is to advance fetal MRI imaging by designing MRI coils specifically for pregnant women and testing recently developed MRI image acquisition techniques. The investigators aim to more reliably obtain higher quality fetal MRI images when compared to curren…

    Stage

    Not phased

    Ages

    18 to 45

    Site

    Boston Children's Hospital, Boston, Massachusetts

    Run by

    Boston Children's Hospital

    See if you can join NCT02840019 on ClinicalTrials.gov

17. Clinical Validation of a Predictive Test for Postpartum Depression

    The goal of this observational study is to develop a blood test that may be predictive of postpartum depression. This Blood test is investigational and not yet FDA approved. Participants will not receive the results of this blood test. Up to 500 pregnant women will be recruited for the study from 2…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Virginia, Charlottesville, Virginia

    Locations

    2 in total

    Run by

    University of Virginia

    See if you can join NCT06831968 on ClinicalTrials.gov

18. A Study of a Test for Postpartum Depression at Home

    The study will seek to prospectively validate the Enlighten Device for prediction of PPD by examining true/false positive and negative rates of the test using PPD outcomes collected through 3 months postpartum; compare the accuracy of biomarkers and algorithm in determining risk for PPD in blood co…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Virginia, Charlottesville, Virginia

    Run by

    University of Virginia

    See if you can join NCT07186309 on ClinicalTrials.gov

19. Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs Syndrome

    The goal of this study is to evaluate whether peroneal electrical nerve stimulation (PNS) using the TOMAC™ device is a feasible, acceptable, and safe non-pharmacologic intervention for managing Restless Legs Syndrome (RLS) during pregnancy. This pilot study will also collect preliminary information…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Rhode Island Hospital, Providence, Rhode Island

    Locations

    2 in total

    Run by

    Rhode Island Hospital

    See if you can join NCT07144631 on ClinicalTrials.gov

20. Gastric Emptying of Water and Sports Drink in Labor

    To determine the half time of the emptying of the stomach of women in early labor with and without epidural pain relief when drinking either water or a carbohydrate-based sports drink.

    Stage

    Not phased

    Ages

    18 to 50

    Site

    Beth Isreal Deaconess Medical Center, Boston, Massachusetts

    Run by

    Beth Israel Deaconess Medical Center

    See if you can join NCT04229043 on ClinicalTrials.gov

21. Impact of the NeuroCuple Device on Pain Management After Cesarean Delivery

    This will be a single-center, sham-controlled, 3 arms, randomized (1:1:1) prospective study in females undergoing cesarean delivery to investigate the impact of NeuroCuple™ non-pharmacological analgesic device for management of postoperative pain. The investigators hypothesize that women treated wi…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Inova Fairfax Medical Campus, Falls Church, Virginia

    Run by

    Inova Health Care Services

    See if you can join NCT07185425 on ClinicalTrials.gov

22. CGM Adherence Compared to Finger-stick Glucose Monitoring in Pregnancies With Type 2 Pregestational Diabetes

    The purpose of this study is to compare patient adherence to blood sugar monitoring during pregnancy using two different measurement methods in pregnancies complicated by pregestational type 2 diabetes (T2DM). Pregnant patients with T2DM are at risk of having larger babies, babies with low sugar le…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Jefferson Health New Jersey, Sewell, New Jersey

    Locations

    2 in total

    Run by

    Thomas Jefferson University

    See if you can join NCT07184775 on ClinicalTrials.gov

23. Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia

    This study's primary purpose is to determine the relationship between aspirin metabolism and markers of metabolic dysfunction among patients at risk for preeclampsia.

    Stage

    Not phased

    Ages

    18 to 45

    Site

    University of Tennessee Medical Center, Knoxville, Tennessee

    Run by

    University of Tennessee Graduate School of Medicine

    See if you can join NCT06802861 on ClinicalTrials.gov

24. Maternal Fetal Device Performance Twins

    Maternal Fetal Monitoring devices assist the health care professional in acquiring, monitoring, and storing fetal and maternal physiologic data which support clinical decision making for pregnant women and assesses the overall fetal health status during pregnancy and delivery. This study aims to su…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Element Materials Technology, Louisville, Colorado

    Run by

    GE Healthcare

    See if you can join NCT06835647 on ClinicalTrials.gov

25. Cocooned Moms Study

    The Cocooned Moms Study is a pre- and post-design study primarily aimed at reducing stress, depressive symptoms, and blood pressure among expectant Black women by providing them with free access to the InovCares mobile app. InovCares is a culturally-sensitive telehealth platform designed for commun…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University Of Miami, Miami, Florida

    Locations

    2 in total

    Run by

    InovCares Connected Comprehensive Healthcare Corporation

    See if you can join NCT06968650 on ClinicalTrials.gov