Pregnancy Clinical Trials

83 studies are recruiting for pregnancy in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Efficacy of Cabergoline in Inhibiting Lactation and Alleviating Breast Symptoms

   The goal of this clinical trial is to learn whether cabergoline can prevent lactation and reduce breast symptoms in pregnant people aged 18 years or older undergoing abortion or pregnancy loss between 12 and 18 weeks of gestation. The main questions it aims to answer are: Does cabergoline decrease …

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Maimonides Medical Center, Brooklyn, New York

   Run by

   Jefferson Drapkin

   See if you can join NCT07492160 on ClinicalTrials.gov

2. Study of Fetal Health Outcomes: Working With a Missouri E-telehealth Platform (The SHOW-ME Study)

   The goal of this clinical trial is to evaluate the potential benefit to patients and providers from using the remote fetal-monitoring system NUVO along with its app to allow for pregnant patients requiring weekly non-stress testing to do so from their homes. The main questions the investigators are…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Missouri, Columbia, Missouri

   Locations

   2 in total

   Run by

   University of Missouri-Columbia

   See if you can join NCT06741735 on ClinicalTrials.gov

3. An Online Intuitive Eating Program for Pregnant Women With Obesity to Support Well-Being

   The goal of this feasibility randomized controlled trial is to assess the feasibility, acceptability, and demand, as well as preliminary effects of an evidence-based Intuitive Eating (IE) intervention among pregnant women who have obesity. The main research questions are: RQ1: What is the feasibili…

   Stage

   Not phased

   Ages

   18 and older

   Site

   San Diego State University, San Diego, California

   Locations

   2 in total

   Run by

   San Diego State University

   See if you can join NCT07792837 on ClinicalTrials.gov

4. Feasibility Trial of the Womb Watch Smartphone App To Assess Fetal Movements

   The surveillance of pregnancies at risk for fetal loss secondary to high-risk maternal or fetal conditions remains a mainstay of perinatal care. Current testing to prevent fetal loss includes the regular use of ultrasound (biophysical profile) or fetal heart rate monitoring (non-stress test) in an …

   Stage

   Not phased

   Ages

   18 to 45

   Site

   Dell Medical School- University of Texas at Austin, Austin, Texas

   Locations

   3 in total

   Run by

   Kenneth Moise MD

   See if you can join NCT07626112 on ClinicalTrials.gov

5. A Repository to Study Host-Microbiome Interactions in Health and Disease

   Background: The microbiome is the bacteria and other microorganisms that live inside and on the body. The microbiome is important for our health. Researchers study how the microbiome help people stay healthy. They study how the microbiome affects the body when people get sick. To do this research, …

   Stage

   Not phased

   Ages

   Any age

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT05656378 on ClinicalTrials.gov

6. Effectiveness of Interventions to Promote Physical Activity During Pregnancy

   Pregnant women are more sedentary (sit, recline, lie down more) on average than non-pregnant women (more than 12 versus less than 8 waking sedentary hours/day). Sedentary behavior has been related to psychological distress, pregnancy weight gain, impaired sleep and very large size infants, while ad…

   Stage

   Not phased

   Ages

   18 to 45

   Site

   Orlando Health, Orlando, Florida

   Run by

   University of Central Florida

   See if you can join NCT07223112 on ClinicalTrials.gov

7. Ripening Approaches for Prompt Induction and Delivery - Sequential Versus Concurrent Dilapan-S and Misoprostol to Achieve Vaginal Delivery (RAPID-DS)

   The purpose of this study is to compare the effectiveness of sequential versus combined multimodal cervical ripening strategies to achieve vaginal delivery within 24 hours among nulliparous patients with singleton, vertex pregnancies at term undergoing induction of labor.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Ochsner Baptist, New Orleans, Louisiana

   Run by

   Ochsner Health System

   See if you can join NCT07717502 on ClinicalTrials.gov

8. Pregnancy Surveillance Program of Patients Exposed to Epidiolex/Epidyolex During Pregnancy

   The purpose of this study is to evaluate pregnancy-related health outcomes in participants who are exposed to Epidiolex/Epidyolex during pregnancy and their infant up to 12 months of life.

   Stage

   Not phased

   Ages

   Any age

   Site

   United Biosource LLC, Morgantown, West Virginia

   Locations

   2 in total

   Run by

   Jazz Pharmaceuticals

   See if you can join NCT06113237 on ClinicalTrials.gov

9. Understanding the Role of Doulas in Supporting People With PMADs

   Detailed Description The doula-led intervention developed during the first phase of this project will be pilot tested for feasibility. Following the recruitment procedures described in the recruitment and retention plan, approximately 75 participants will be enrolled into the study. Twenty-five of …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Montana, Missoula, Montana

   Run by

   University of Montana

   See if you can join NCT05763537 on ClinicalTrials.gov

10. Study of Ceftriaxone and Benzathine Penicillin G During Pregnancy

    IMPAACT 2044 is a study to characterize the pharmacokinetics (PK) and safety of ceftriaxone and benzathine penicillin G during pregnancy. Up to 78 pregnant women receiving (1) ceftriaxone for indications other than syphilis or (2) benzathine penicillin G for treatment of syphilis from non-study cli…

    Stage

    Not phased

    Ages

    Any age

    Site

    Site 5048, USC - Maternal Child Adolescent/Adult Center, Los Angeles, California

    Locations

    9 in total

    Run by

    International Maternal Pediatric Adolescent AIDS Clinical Trials Group

    See if you can join NCT07207876 on ClinicalTrials.gov

11. Maternal Smoking Cessation and Pediatric Obesity Prevention

    The objective of this study is to test the effect of smoking cessation in pregnancy or in lactation on preventing rapid infant adiposity gain. Investigators propose a randomized, controlled experiment among smoking pregnant women from 1st prenatal care visit through 6 months of postpartum period. T…

    Stage

    Not phased

    Ages

    18 to 39

    Site

    Division of Behavioral Medicine Department of Pediatrics Jacobs School of Medicine and Biomedical Sciences State University of New York at Buffalo, Buffalo, New York

    Run by

    State University of New York at Buffalo

    See if you can join NCT03514602 on ClinicalTrials.gov

12. Induction of Labor in Morbidly Obese Patients

    The goal of this randomized control trial is to compare different doses of Misoprostol (25 mcg vs 50 mcg) in induction of labor (IOL) in morbidly obese patients with BMI >40. It is known that morbid obesity is a risk factor for failed IOL and ultimately cesarean delivery (CD.) If the rates of vagin…

    Stage

    EARLY_Phase 1

    Ages

    18 and older

    Site

    University of Maryland Medical Center, Baltimore, Maryland

    Run by

    University of Maryland, Baltimore

    See if you can join NCT06199154 on ClinicalTrials.gov

13. Michigan Healthy Mom (MI-MOM) Pregnancy Improvement Web Application Trial

    The purpose of this research study is to see if using the MI MOM App improves pregnancy and postpartum health. There are two study groups, where one group is "treatment as usual" and the other is the "MI MOM App" group. Both groups will be asked to answer questions about their pregnancy health. Res…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Shiawasee Health Department, Corunna, Michigan

    Locations

    8 in total

    Run by

    Michigan State University

    See if you can join NCT07213284 on ClinicalTrials.gov

14. Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

    The lack of postpartum primary care coordination is a missed opportunity to increase primary care engagement and manage chronic conditions early in life, especially for the >30% of pregnant people who have or are at risk for these conditions. This study aims to increase postpartum primary care enga…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT06557005 on ClinicalTrials.gov

15. Automated Insulin for Management of Intrapartum Glycemia

    The goal of this clinical trial is learn if automated insulin delivery (AID) systems can be used for glucose management during labor/delivery for pregnant people with type 1 diabetes (T1D). The main questions this study aims to answer are * What are the neonatal glycemic outcomes with use of AID sy…

    Stage

    Not phased

    Ages

    18 to 55

    Site

    University of California, Los Angeles, Los Angeles, California

    Locations

    3 in total

    Run by

    University of California, San Francisco

    See if you can join NCT06883344 on ClinicalTrials.gov

16. Preliminary Effectiveness of Enhanced Text Message + Incentives

    This study is a preliminary evaluation of a smoking cessation intervention designed for pregnant women that combines text message support and financial incentives. The aims of this study are to determine the preliminary feasibility and acceptability of text message + incentives (intervention) vs. t…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Kansas Medical Center, Kansas City, Kansas

    Run by

    University of Kansas Medical Center

    See if you can join NCT07420621 on ClinicalTrials.gov

17. Prospective Evaluation of an AI Diagnostic Ultrasound Tool for Fetal Weight Estimation

    Purpose: The primary objective of this study is to assess the diagnostic accuracy of an AI-enabled ultrasound tool for estimating fetal weight Participants: 1,000 pregnant individuals Procedures (methods): This prospective diagnostic accuracy study will enroll 1,000 pregnant individuals within one …

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of North Carolina, Chapel Hill, North Carolina

    Locations

    5 in total

    Run by

    University of North Carolina, Chapel Hill

    See if you can join NCT07661433 on ClinicalTrials.gov

18. Culturally Engaged REcovery: MOms Connected Through Native communitY

    Pregnant and postpartum American Indian and Alaska Native people (Native mothers) face a more than two-fold higher risk of maternal mortality compared to non-Hispanic White mothers. Deaths related to substance use (SU) and mental health conditions are a leading cause of preventable maternal mortali…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Sacred Circle Healthcare, Salt Lake City, Utah

    Run by

    University of Utah

    See if you can join NCT06747442 on ClinicalTrials.gov

19. Breathing for Two: Inspiratory Muscle Strength Training for Supporting Healthy Blood Pressure in Pregnancy

    This is an interventional study that will test whether a breathing exercise called Inspiratory Muscle Strength Training (IMST) can safely and effectively lower blood pressure during late pregnancy. The goal is to see if a home-based breathing training can help prevent or reduce high blood pressure …

    Stage

    EARLY_Phase 1

    Ages

    18 to 55

    Site

    Banner University Medical Center, Tucson, Arizona

    Run by

    University of Arizona

    See if you can join NCT07687745 on ClinicalTrials.gov

20. Poi for Mama: a Pilot to Improve Maternal Microbiome and Gestational Diabetes Risk

    This investigator-initiated, non-randomized pilot study evaluates the effect of daily consumption of fermented poi on the maternal microbiome and gestational diabetes risk during pregnancy. Fifty pregnant participants between approximately 12 and 24 weeks of gestation will receive one pound of poi …

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Hawai'i Cancer Center, Honolulu, Hawaii

    Locations

    3 in total

    Run by

    University of Hawaii

    See if you can join NCT07446205 on ClinicalTrials.gov

21. CGM for Management of Type 2 Diabetes in Pregnancy

    The goal of this clinical trial is to learn if continuous glucose monitoring works better than self-monitoring of blood glucose (fingersticks) to treat type 2 diabetes in pregnancy. It will also learn about all risk factors (biologic, personal, social) for maternal and infant complications in type …

    Stage

    Not phased

    Ages

    18 to 50

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Locations

    7 in total

    Run by

    University of Alabama at Birmingham

    See if you can join NCT06628453 on ClinicalTrials.gov

22. CARRII Native Intervention Optimization Trial

    The purpose of this study is to identify the best combination of new intervention components to use with CARRII, the first automated online intervention for alcohol-exposed pregnancies (AEP). This intervention is specifically designed for Native women and others who can become pregnant. Our goal is…

    Stage

    Not phased

    Ages

    18 to 44

    Site

    University of Virginia Fontaine Research Park, Charlottesville, Virginia

    Run by

    University of Virginia

    See if you can join NCT07547696 on ClinicalTrials.gov

23. Maternal And Infant Antipsychotic Study

    The goal of this observational study is to learn about maternal psychiatric course and infant development in pregnant individuals with severe mental illness, comparing those treated with antipsychotics to those treated with other medications or without medication. The main questions it aims to answ…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Icahn School of Medicine at Mount Sinai, New York, New York

    Run by

    Icahn School of Medicine at Mount Sinai

    See if you can join NCT06049953 on ClinicalTrials.gov

24. Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)

    Pregnant women with a primary diagnosis of posttraumatic stress disorder (PTSD) (PTSD Checklist for DSM-5 (PCL-5) score > 33) will be randomized to receive conventional cognitive processing therapy (CPT) (60-min session once/week for 12 weeks) or massed CPT (mCPT) (an intensive schedule of 12 60-mi…

    Stage

    Not phased

    Ages

    18 to 46

    Site

    University of Texas at Austin, Dell Medical School, Department of Psychiatry, Austin, Texas

    Run by

    University of Texas at Austin

    See if you can join NCT07060144 on ClinicalTrials.gov

25. Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years

    The goal of this clinical trial is to test the effectiveness of evidence-based Screening, Brief Intervention, and Referral to Treatment (SBIRT) among adult patients who screen positive to one or more risky alcohol or substance use behaviors while seeking care at a sexual and reproductive health (SR…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Greater Boston Health Center, Boston, Massachusetts

    Locations

    4 in total

    Run by

    Emory University

    See if you can join NCT05910580 on ClinicalTrials.gov