Pregnancy Clinical Trials

86 studies are recruiting for pregnancy in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Probiotic Supplementation in Optimizing Iron and Hematological Status Among Pregnant Females

   Maternal iron deficiency (ID) and iron deficiency anemia (IDA) is associated with maternal and infant mortality, spontaneous preterm birth, maternal postpartum hemorrhage, and neurocognitive defects in the neonate. Therefore, preventing maternal IDA in at-risk women is critical. The standard approa…

   Stage

   Phase 2

   Ages

   18 to 45

   Site

   University of Illinois at Chicago, Chicago, Illinois

   Run by

   University of Illinois Chicago

   See if you can join NCT07076849 on ClinicalTrials.gov

2. Impact of Standardization on Outcomes Following Cervical Ripening

   The primary purpose of this study is to determine if vaginal delivery rate is impacted by the use of standardized methods of cervical ripening. Additional outcomes will be evaluated including maternal and fetal outcomes of labor.

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Sidney & Lois Eskenazi Hospital, Indianapolis, Indiana

   Run by

   Indiana University

   See if you can join NCT07576881 on ClinicalTrials.gov

3. Impact of the NeuroCuple Device on Pain Management After Cesarean Delivery

   This will be a single-center, sham-controlled, 3 arms, randomized (1:1:1) prospective study in females undergoing cesarean delivery to investigate the impact of NeuroCuple™ non-pharmacological analgesic device for management of postoperative pain. The investigators hypothesize that women treated wi…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Inova Fairfax Medical Campus, Falls Church, Virginia

   Run by

   Inova Health Care Services

   See if you can join NCT07185425 on ClinicalTrials.gov

4. CHEER Oral Health in Pregnancy Study

   Many pregnant people don't get the dental care they need, even though it's safe and important. The CHEER Study offers free dental check-ups, cleanings, and supplies to help participants take care of their teeth and gums during pregnancy. The purpose of this research study is to compare two types of…

   Stage

   Not phased

   Ages

   18 and older

   Site

   UCSF Dental Center, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT07377344 on ClinicalTrials.gov

5. Prospective Evaluation of an AI Diagnostic Ultrasound Tool for Fetal Weight Estimation

   Purpose: The primary objective of this study is to assess the diagnostic accuracy of an AI-enabled ultrasound tool for estimating fetal weight Participants: 1,000 pregnant individuals Procedures (methods): This prospective diagnostic accuracy study will enroll 1,000 pregnant individuals within one …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of North Carolina, Chapel Hill, North Carolina

   Locations

   6 in total

   Run by

   University of North Carolina, Chapel Hill

   See if you can join NCT07661433 on ClinicalTrials.gov

6. Pregnancy Surveillance Program of Patients Exposed to Epidiolex/Epidyolex During Pregnancy

   The purpose of this study is to evaluate pregnancy-related health outcomes in participants who are exposed to Epidiolex/Epidyolex during pregnancy and their infant up to 12 months of life.

   Stage

   Not phased

   Ages

   Any age

   Site

   United Biosource LLC, Morgantown, West Virginia

   Locations

   3 in total

   Run by

   Jazz Pharmaceuticals

   See if you can join NCT06113237 on ClinicalTrials.gov

7. Feasibility of an ADAPTive Intervention to Improve Food Security and Maternal-Child Health

   Food insecurity affects up to 30% of pregnancies and leads to worse health in pregnant people and their children, including an increased risk of gestational diabetes, pre-term birth, and future cardiometabolic chronic conditions (e.g., type 2 diabetes and obesity). Interventions are being utilized …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Wake Forest University Health Sciences, Winston-Salem, North Carolina

   Run by

   Wake Forest University Health Sciences

   See if you can join NCT06942598 on ClinicalTrials.gov

8. MitoQ to Improve Vascular Funciton in Preeclampsia

   Preeclampsia is a leading cause of maternal and neonatal morbidity and mortality. There is a lack of effective therapeutics for prevention or treatment. Our previous ex vivo work demonstrated that mitochondrial-antioxidants can reverse placental microvascular damage. Therefore, this study will eval…

   Stage

   Not phased

   Ages

   18 to 50

   Site

   Froedtert & the Medical College of Wisconsin, Milwaukee, Wisconsin

   Run by

   Medical College of Wisconsin

   See if you can join NCT07229261 on ClinicalTrials.gov

9. Deconstructing Maternal Burdens: Doulas and the Community Unite for Health

   This study is a randomized controlled trial comparing two models of doula support for pregnant individuals enrolled in Medicaid: an enhanced doula support model, in which support starts earlier in pregnancy, occurs more frequently, and continues through the first year after birth, versus the standa…

   Stage

   Not phased

   Ages

   15 to 49

   Site

   University of Florida, Gainesville, Florida

   Run by

   University of Florida

   See if you can join NCT07799805 on ClinicalTrials.gov

10. Supporting Just-In-Time Consent for Prenatal Screening: The INFORM Study

    This clinical trial is about prenatal genetic screening. It will test an intervention to help people make decisions about screening. The intervention is a short set of information cards about screening. This intervention is for pregnant participants. They will use the intervention on their mobile p…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Zuckerberg Chan San Francisco General Hospital, San Francisco, California

    Locations

    3 in total

    Run by

    Case Western Reserve University

    See if you can join NCT07557303 on ClinicalTrials.gov

11. Efficacy of Cabergoline in Inhibiting Lactation and Alleviating Breast Symptoms

    The goal of this clinical trial is to learn whether cabergoline can prevent lactation and reduce breast symptoms in pregnant people aged 18 years or older undergoing abortion or pregnancy loss between 12 and 18 weeks of gestation. The main questions it aims to answer are: Does cabergoline decrease …

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Maimonides Medical Center, Brooklyn, New York

    Run by

    Jefferson Drapkin

    See if you can join NCT07492160 on ClinicalTrials.gov

12. Study of Fetal Health Outcomes: Working With a Missouri E-telehealth Platform (The SHOW-ME Study)

    The goal of this clinical trial is to evaluate the potential benefit to patients and providers from using the remote fetal-monitoring system NUVO along with its app to allow for pregnant patients requiring weekly non-stress testing to do so from their homes. The main questions the investigators are…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Missouri, Columbia, Missouri

    Locations

    2 in total

    Run by

    University of Missouri-Columbia

    See if you can join NCT06741735 on ClinicalTrials.gov

13. An Online Intuitive Eating Program for Pregnant Women With Obesity to Support Well-Being

    The goal of this feasibility randomized controlled trial is to assess the feasibility, acceptability, and demand, as well as preliminary effects of an evidence-based Intuitive Eating (IE) intervention among pregnant women who have obesity. The main research questions are: RQ1: What is the feasibili…

    Stage

    Not phased

    Ages

    18 and older

    Site

    San Diego State University, San Diego, California

    Locations

    2 in total

    Run by

    San Diego State University

    See if you can join NCT07792837 on ClinicalTrials.gov

14. Feasibility Trial of the Womb Watch Smartphone App To Assess Fetal Movements

    The surveillance of pregnancies at risk for fetal loss secondary to high-risk maternal or fetal conditions remains a mainstay of perinatal care. Current testing to prevent fetal loss includes the regular use of ultrasound (biophysical profile) or fetal heart rate monitoring (non-stress test) in an …

    Stage

    Not phased

    Ages

    18 to 45

    Site

    Dell Medical School- University of Texas at Austin, Austin, Texas

    Locations

    3 in total

    Run by

    Kenneth Moise MD

    See if you can join NCT07626112 on ClinicalTrials.gov

15. A Repository to Study Host-Microbiome Interactions in Health and Disease

    Background: The microbiome is the bacteria and other microorganisms that live inside and on the body. The microbiome is important for our health. Researchers study how the microbiome help people stay healthy. They study how the microbiome affects the body when people get sick. To do this research, …

    Stage

    Not phased

    Ages

    Any age

    Site

    National Institutes of Health Clinical Center, Bethesda, Maryland

    Run by

    National Institute of Allergy and Infectious Diseases (NIAID)

    See if you can join NCT05656378 on ClinicalTrials.gov

16. Effectiveness of Interventions to Promote Physical Activity During Pregnancy

    Pregnant women are more sedentary (sit, recline, lie down more) on average than non-pregnant women (more than 12 versus less than 8 waking sedentary hours/day). Sedentary behavior has been related to psychological distress, pregnancy weight gain, impaired sleep and very large size infants, while ad…

    Stage

    Not phased

    Ages

    18 to 45

    Site

    Orlando Health, Orlando, Florida

    Run by

    University of Central Florida

    See if you can join NCT07223112 on ClinicalTrials.gov

17. Ripening Approaches for Prompt Induction and Delivery - Sequential Versus Concurrent Dilapan-S and Misoprostol to Achieve Vaginal Delivery (RAPID-DS)

    The purpose of this study is to compare the effectiveness of sequential versus combined multimodal cervical ripening strategies to achieve vaginal delivery within 24 hours among nulliparous patients with singleton, vertex pregnancies at term undergoing induction of labor.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Ochsner Baptist, New Orleans, Louisiana

    Run by

    Ochsner Health System

    See if you can join NCT07717502 on ClinicalTrials.gov

18. Understanding the Role of Doulas in Supporting People With PMADs

    Detailed Description The doula-led intervention developed during the first phase of this project will be pilot tested for feasibility. Following the recruitment procedures described in the recruitment and retention plan, approximately 75 participants will be enrolled into the study. Twenty-five of …

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Montana, Missoula, Montana

    Run by

    University of Montana

    See if you can join NCT05763537 on ClinicalTrials.gov

19. Study of Ceftriaxone and Benzathine Penicillin G During Pregnancy

    IMPAACT 2044 is a study to characterize the pharmacokinetics (PK) and safety of ceftriaxone and benzathine penicillin G during pregnancy. Up to 78 pregnant women receiving (1) ceftriaxone for indications other than syphilis or (2) benzathine penicillin G for treatment of syphilis from non-study cli…

    Stage

    Not phased

    Ages

    Any age

    Site

    Site 5048, USC - Maternal Child Adolescent/Adult Center, Los Angeles, California

    Locations

    9 in total

    Run by

    International Maternal Pediatric Adolescent AIDS Clinical Trials Group

    See if you can join NCT07207876 on ClinicalTrials.gov

20. Maternal Smoking Cessation and Pediatric Obesity Prevention

    The objective of this study is to test the effect of smoking cessation in pregnancy or in lactation on preventing rapid infant adiposity gain. Investigators propose a randomized, controlled experiment among smoking pregnant women from 1st prenatal care visit through 6 months of postpartum period. T…

    Stage

    Not phased

    Ages

    18 to 39

    Site

    Division of Behavioral Medicine Department of Pediatrics Jacobs School of Medicine and Biomedical Sciences State University of New York at Buffalo, Buffalo, New York

    Run by

    State University of New York at Buffalo

    See if you can join NCT03514602 on ClinicalTrials.gov

21. Induction of Labor in Morbidly Obese Patients

    The goal of this randomized control trial is to compare different doses of Misoprostol (25 mcg vs 50 mcg) in induction of labor (IOL) in morbidly obese patients with BMI >40. It is known that morbid obesity is a risk factor for failed IOL and ultimately cesarean delivery (CD.) If the rates of vagin…

    Stage

    EARLY_Phase 1

    Ages

    18 and older

    Site

    University of Maryland Medical Center, Baltimore, Maryland

    Run by

    University of Maryland, Baltimore

    See if you can join NCT06199154 on ClinicalTrials.gov

22. Michigan Healthy Mom (MI-MOM) Pregnancy Improvement Web Application Trial

    The purpose of this research study is to see if using the MI MOM App improves pregnancy and postpartum health. There are two study groups, where one group is "treatment as usual" and the other is the "MI MOM App" group. Both groups will be asked to answer questions about their pregnancy health. Res…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Shiawasee Health Department, Corunna, Michigan

    Locations

    8 in total

    Run by

    Michigan State University

    See if you can join NCT07213284 on ClinicalTrials.gov

23. Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

    The lack of postpartum primary care coordination is a missed opportunity to increase primary care engagement and manage chronic conditions early in life, especially for the >30% of pregnant people who have or are at risk for these conditions. This study aims to increase postpartum primary care enga…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT06557005 on ClinicalTrials.gov

24. Automated Insulin for Management of Intrapartum Glycemia

    The goal of this clinical trial is learn if automated insulin delivery (AID) systems can be used for glucose management during labor/delivery for pregnant people with type 1 diabetes (T1D). The main questions this study aims to answer are * What are the neonatal glycemic outcomes with use of AID sy…

    Stage

    Not phased

    Ages

    18 to 55

    Site

    University of California, Los Angeles, Los Angeles, California

    Locations

    3 in total

    Run by

    University of California, San Francisco

    See if you can join NCT06883344 on ClinicalTrials.gov

25. Preliminary Effectiveness of Enhanced Text Message + Incentives

    This study is a preliminary evaluation of a smoking cessation intervention designed for pregnant women that combines text message support and financial incentives. The aims of this study are to determine the preliminary feasibility and acceptability of text message + incentives (intervention) vs. t…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Kansas Medical Center, Kansas City, Kansas

    Run by

    University of Kansas Medical Center

    See if you can join NCT07420621 on ClinicalTrials.gov