Pregnancy Related Clinical Trials

50 studies are recruiting for pregnancy related in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Prenatal Education on Environmental Exposures During Pregnancy Study (PEEPS)

   The purpose of this project is to reduce maternal environmental exposures to toxicants through a patient education program designed to help pregnant women learn about exposure through consumption of contaminated seafood and to be able to use the lessons they learn to have a better understanding of …

   Stage

   Not phased

   Ages

   18 and older

   Site

   St Vincent's Hope Clinics, Galveston, Texas

   Locations

   2 in total

   Run by

   The University of Texas Medical Branch, Galveston

   See if you can join NCT07758114 on ClinicalTrials.gov

2. MAMA Tot - Healthy Weight Parallel Study

   The overall objective of this proposal is to conduct a longitudinal prospective study of healthy pregnant women and their offspring to determine which antenatal maternal exercise mode(s) will have the greatest impact on maternal and infant cardiometabolic health. This information may lead to modifi…

   Stage

   Not phased

   Ages

   18 to 40

   Site

   East Carolina University, Greenville, North Carolina

   Run by

   East Carolina University

   See if you can join NCT06598098 on ClinicalTrials.gov

3. Observational Safety Study in Women With Neuromyelitis Optica Spectrum Disorder (NMOSD) Exposed to UPLIZNA® During Pregnancy

   This is an observational study to monitor female participants exposed to UPLIZNA during pregnancy. This study requires voluntary reporting of pregnancies in female participants with NMOSD exposed to UPLIZNA during pregnancy or within 6 months preceding conception. Pregnancy-related data, potential …

   Stage

   Not phased

   Ages

   15 and older

   Site

   University of Colorado Denver, Aurora, Colorado

   Run by

   Amgen

   See if you can join NCT05909761 on ClinicalTrials.gov

4. Odevixibat Pregnancy and Lactation Surveillance Program: A Study to Evaluate the Safety of Odevixibat During Pregnancy and/or Lactation

   The participants of this study will be of any age who are exposed to at least 1 dose of odevixibat at any time during pregnancy (from 1 day prior to conception to pregnancy outcome) and/or at any time during lactation (up to 12 months of infant age or weaning, whichever comes first. This study will…

   Stage

   Not phased

   Ages

   Any age

   Site

   Virtual Research Coordination Center Odevixibat (BYLVAY) Pregnancy Surveillance Program, Wilmington, North Carolina

   Run by

   Ipsen

   See if you can join NCT06258902 on ClinicalTrials.gov

5. Elafibranor Pregnancy Surveillance Program: A Study to Evaluate the Safety of Elafibranor During Pregnancy

   The study will include participants who were exposed to at least one dose of elafibranor either within the three weeks before conception or at any time during pregnancy (based on estimated last menstrual period [LMP]). Information will be collected from participants, their healthcare providers, pub…

   Stage

   Not phased

   Ages

   Any age

   Site

   Virtual Research Coordination Center, Wilmington, North Carolina

   Run by

   Ipsen

   See if you can join NCT07556913 on ClinicalTrials.gov

6. Interprofessional Simulation Program for Clinical Resilience and Empathy: Project INSPIRE

   The goal of this clinical trial is to develop and evaluate INSPIRE, an intervention for healthcare teams to improve care for individuals with substance use disorder (SUD) during their peri-delivery care. The main question it aims to answer is whether healthcare provider stigmas and behaviors change…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Utah Health, Salt Lake City, Utah

   Run by

   University of Utah

   See if you can join NCT07707115 on ClinicalTrials.gov

7. Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

   This study will be a 12-month prospective, genotype-blinded longitudinal observational study with current standard of clinical care. This study will enroll 100 pregnant women with OUD at UPMC Hospitals with its high volumes. Because of the observational nature of the study, the anticipated dropout …

   Stage

   Not phased

   Ages

   18 and older

   Site

   UPMC Magee-Womens Hospital, Pittsburgh, Pennsylvania

   Run by

   Ilana Hull

   See if you can join NCT05942313 on ClinicalTrials.gov

8. Commercial or Open Source Closed Loop Impact on Pregnancy Study

   The goal of this observational study is to better understand what happens when pregnant people with type 1 diabetes (T1D) use automated insulin delivery (AID) systems. The main questions this study aims to answer are: * What are the maternal and neonatal outcomes with AID system use in pregnancy? *…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California, San Francisco, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT06654713 on ClinicalTrials.gov

9. Building TrUst and UNiting Teams Through DouLa partnErship - BUNDLE

   The BUNDLE study is a prospective mixed-methods study focused on the early integration of community doula into prenatal care. The study will have three phases: Phase 1 is the qualitative phase of conducting focus groups with Black/African American (AA) birthing people and with medical and community…

   Stage

   Not phased

   Ages

   18 to 65

   Site

   Medical College of Wisconsin, Milwaukee, Wisconsin

   Run by

   Medical College of Wisconsin

   See if you can join NCT05993689 on ClinicalTrials.gov

10. Reducing Psychological Barriers to PrEP Persistence Among Pregnant and Postpartum Women in Cape Town, South Africa

    Pregnant women in South Africa (SA) are at high risk of HIV acquisition. Pre-exposure prophylaxis (PrEP) use during pregnancy is both safe and effective in preventing HIV. However, posttraumatic stress (associated with intimate partner violence and/or other traumas) and depression negatively impact…

    Stage

    Not phased

    Ages

    15 and older

    Site

    Gugulethu Midwife Obstetric Unit (MOU), Cape Town, Western Cape

    Locations

    2 in total

    Run by

    Boston University Charles River Campus

    See if you can join NCT05624931 on ClinicalTrials.gov

11. Better Lifestyle Counseling for African American Women During Pregnancy

    The purpose of this randomized controlled trial is to establish the effectiveness of a culturally targeted and individually tailored behavioral intervention to promote maternal glucose metabolism in African American women.

    Stage

    Not phased

    Ages

    18 to 40

    Site

    University of Illinois at Chicago, Chicago, Illinois

    Locations

    2 in total

    Run by

    University of Illinois at Chicago

    See if you can join NCT05234125 on ClinicalTrials.gov

12. Upper vs Lower Extremity BP in Spinal Cesarean Using ClearSight

    This is a single-center, prospective observational study in patients undergoing cesarean delivery under spinal or combined spinal-epidural anesthesia. It compares whether continuous noninvasive hemodynamic measurements from the lower extremity (toe) better predict neonatal outcomes than upper extre…

    Stage

    Not phased

    Ages

    18 and older

    Site

    The Ohio State University, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT07685730 on ClinicalTrials.gov

13. Trial of Community-based Patient Navigation

    This study will test the effectiveness of a community-based patient navigator intervention from mid-pregnancy through 12 month postpartum for a high-risk population of medically underserved women. The RCT will enroll 540 pregnant women before 20 weeks of pregnancy and randomly allocate them into tw…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Grady Memorial Hospital, Atlanta, Georgia

    Run by

    Emory University

    See if you can join NCT05588245 on ClinicalTrials.gov

14. Impact of Lactation Antenatal Teaching by Clinicians and Healthcare Providers

    The purpose of this study is to increase the rate of exclusive breastfeeding at 6 weeks postpartum in the Inland Empire by addressing inadequate antenatal breastfeeding education for patients.

    Stage

    Not phased

    Ages

    18 to 45

    Site

    Loma Linda University Faculty Medical Offices, Loma Linda, California

    Run by

    Loma Linda University

    See if you can join NCT07560553 on ClinicalTrials.gov

15. Effects of Systematic Cervical Exam Training on Labor and Delivery Care

    All physicians, nurses, and nurse midwives working on Labor and Delivery will be required to complete cervical exam simulation training. Data before and after institution of the training will be compared to determine if the training leads to less cervical exams during labor and increases consistenc…

    Stage

    Not phased

    Ages

    Any age

    Site

    Wake Forest University Health Sciences, Winston-Salem, North Carolina

    Run by

    Wake Forest University Health Sciences

    See if you can join NCT04421768 on ClinicalTrials.gov

16. WAKIX® (Pitolisant) Pregnancy Registry

    The WAKIX (pitolisant) Pregnancy Registry is a US-based, prospective, observational cohort study designed to evaluate the association between pitolisant exposure during pregnancy and subsequent maternal, fetal, and infant outcomes.

    Stage

    Not phased

    Ages

    Any age

    Site

    Evidera (PPD), Morrisville, North Carolina

    Run by

    Harmony Biosciences Management, Inc.

    See if you can join NCT05536011 on ClinicalTrials.gov

17. Maternal Intake of Eggs and Infant Neurodevelopment

    The fetal brain requires DHA, choline, lutein, and zeaxanthin (L/Z) for development, dependent on maternal intake during pregnancy. However, many pregnant women do not meet daily requirements through diet or prenatal vitamins. Egg yolks are rich in choline, and women who consume eggs daily are more…

    Stage

    Not phased

    Ages

    18 and older

    Site

    The University of Kansas Medical Center, Kansas City, Kansas

    Run by

    University of Kansas Medical Center

    See if you can join NCT07583186 on ClinicalTrials.gov

18. Physiological-based Pharmacokinetics Approach to Medication Exposure During Pregnancy and Breastfeeding

    This project focuses on anti-seizure medication (ASM) clearance and physiological factors determining blood concentrations in pregnant adult women with epilepsy and amounts of exposure to their unborn children and nursing infants.

    Stage

    Not phased

    Ages

    18 to 45

    Site

    University of Pittsburgh, Pittsburgh, Pennsylvania

    Run by

    University of Pittsburgh

    See if you can join NCT05450978 on ClinicalTrials.gov

19. Nourishing Tomorrow: Role of Medically Tailored Groceries in Addressing Food Insecurity During Pregnancy

    Medically tailored groceries (MTG), involving grocery items to be prepared at home, selected by a nutritional professional based on a treatment plan, is a growing approach adopted by healthcare systems to address food insecurity in their patient populations, a leading contribution to health dispari…

    Stage

    Not phased

    Ages

    18 to 55

    Site

    MetroHealth Medical Center, Cleveland, Ohio

    Locations

    2 in total

    Run by

    Case Western Reserve University

    See if you can join NCT06965530 on ClinicalTrials.gov

20. Accountability for Care Through Undoing Racism & Equity for Moms

    This project-also known as "Accountability for Care through Undoing Racism \& Equity for Moms" or ACURE4Moms-aims to reduce Black-White maternal health disparities using multi-level interventions designed to decrease bias in prenatal care, improve care coordination, and increase social support. ACU…

    Stage

    Not phased

    Ages

    12 to 99

    Site

    University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

    Run by

    University of North Carolina, Chapel Hill

    See if you can join NCT05484804 on ClinicalTrials.gov

21. Understanding Practices of Lactation and Infant Feeding Together With Women With HIV in the United States

    IMPAACT 2046/UPLIFT (Understanding Practices of Lactation and Infant Feeding decisions Together with women with HIV) is a multi-site, mixed-methods, observational cohort study. The purpose of the study is to explore infant feeding preferences, practices, and outcomes among mothers with HIV and thei…

    Stage

    Not phased

    Ages

    Any age

    Site

    University of Colorado, Denver (CRS 5052), Aurora, Colorado

    Locations

    11 in total

    Run by

    International Maternal Pediatric Adolescent AIDS Clinical Trials Group

    See if you can join NCT07293559 on ClinicalTrials.gov

22. Perineal Massage Using A Pelvic Wand During Pregnancy

    There is limited research on the optimal strategy to reduce obstetric laceration, postpartum urinary retention, and postpartum pelvic pain. In systematic reviews, clinician-directed massage of the perineal muscles at the time of birth and patient directed massage of the perineal muscles in the thir…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    Beth Israel Deaconess Medical Center, Boston, Massachusetts

    Run by

    Beth Israel Deaconess Medical Center

    See if you can join NCT06986824 on ClinicalTrials.gov

23. Comparison of Two Salpingectomy Techniques for Sterilization at the Time of Cesarean Delivery

    One in three women of reproductive age utilize tubal sterilization for contraception, and sterilization is often requested at time of cesarean delivery. Complete salpingectomy for the purpose of permanent sterilization at the time of cesarean birth is increasingly being performed worldwide. A prefe…

    Stage

    Not phased

    Ages

    21 and older

    Site

    Inova Fairfax Medical campus, Falls Church, Virginia

    Run by

    Inova Health Care Services

    See if you can join NCT06273683 on ClinicalTrials.gov

24. Mobile Application-based Exercise Intervention for Pregnant Women

    The overarching goal of this randomized controlled clinical trial is to test the efficacy of the mHealth app (BumptUp) for improving physical activity levels among pregnant and postpartum women in a rural setting. Secondary outcomes include weight status, dietary intake, glucose tolerance, blood pr…

    Stage

    Not phased

    Ages

    18 to 44

    Site

    Rachel Tinius, Bowling Green, Kentucky

    Run by

    Western Kentucky University

    See if you can join NCT05849649 on ClinicalTrials.gov

25. Prophylactic Transfusion In Pregnant in Women With Sickle Cell Disease

    The goal of this study is to determine if there is a positive effect of prophylactic red blood cell (RBC) transfusion of leukoreduced, ABO, Rh (D/Cc/Ee) and Kell matched blood compared to standard of care on the number of episodes of acute sickle cell disease (SCD) manifestations or pregnancy-relat…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    Grady Health System, Atlanta, Georgia

    Run by

    Emory University

    See if you can join NCT06979492 on ClinicalTrials.gov