Pregnancy Complications Clinical Trials

26 studies are recruiting for pregnancy complications in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. The Periviable GOALS Decision Support Tool

    The Periviable GOALS (Getting Optimal Alignment around Life Support) decision support tool (DST) is meant to facilitate informed shared decision-making regarding neonatal resuscitation for families facing the threat of a periviable delivery (deliveries occurring between 22 0/7 - 25 6/7 weeks gestat…

    Stage
    Not phased
    Ages
    18 and older
    Site
    The University of California San Diego, San Diego, California
    Locations
    12 in total
    Run by
    Indiana University
  2. Advancing Stillbirth Prevention Through Innovative Risk Evaluation (ASPIRE) Clinical Study

    ASPIRE will be a multi-site, prospective, two-part longitudinal, noninterventional observational cohort study of nulliparous singleton pregnant women to evaluate biomarkers from blood and ocular imaging for prediction of pregnancy complications [i.e., preeclampsia (PE), fetal growth restriction (FG…

    Stage
    Not phased
    Ages
    18 to 99
    Site
    Woman's Hospital, Baton Rouge, Louisiana
    Locations
    2 in total
    Run by
    Medicines360
  3. Deconstructing Maternal Burdens: Doulas and the Community Unite for Health

    This study is a randomized controlled trial comparing two models of doula support for pregnant individuals enrolled in Medicaid: an enhanced doula support model, in which support starts earlier in pregnancy, occurs more frequently, and continues through the first year after birth, versus the standa…

    Stage
    Not phased
    Ages
    15 to 49
    Site
    University of Florida, Gainesville, Florida
    Run by
    University of Florida
  4. Treatment With Aspirin After Preeclampsia: TAP Trial

    The objective of this research project is to conduct a single-site pilot trial to assess the feasibility and effect of low-dose aspirin to augment vascular recovery in the immediate postpartum period after preeclampsia through two specific aims: 1) to pilot test the feasibility of conducting a rand…

    Stage
    Phase 4
    Ages
    18 to 55
    Site
    University of Pittsburgh Magee-Womens Hospital, Pittsburgh, Pennsylvania
    Run by
    Malamo Countouris
  5. Feasibility Trial of the Womb Watch Smartphone App To Assess Fetal Movements

    The surveillance of pregnancies at risk for fetal loss secondary to high-risk maternal or fetal conditions remains a mainstay of perinatal care. Current testing to prevent fetal loss includes the regular use of ultrasound (biophysical profile) or fetal heart rate monitoring (non-stress test) in an …

    Stage
    Not phased
    Ages
    18 to 45
    Site
    Dell Medical School- University of Texas at Austin, Austin, Texas
    Locations
    3 in total
    Run by
    Kenneth Moise MD
  6. Boston Birth Cohort Study

    Early life exposures may lead to adverse effects on health in later life. The Boston birth Cohort study is designed to study a broad array of early life factors and their effects on maternal and child health outcomes across the life course.

    Stage
    Not phased
    Ages
    0 to 50
    Site
    Boston Medical Center, Boston, Massachusetts
    Run by
    Johns Hopkins Bloomberg School of Public Health
  7. MOCHA: Embedded Inpatient Mental Health Care for High-Risk Perinatal Patients

    Pregnant and postpartum patients hospitalized for medical complications experience high rates of depression, anxiety, and trauma-related symptoms, yet access to timely psychiatric care during obstetric hospitalization is limited. Project MOCHA integrates early mental health screening, trauma-inform…

    Stage
    Not phased
    Ages
    18 to 100
    Site
    Riley Hospital for Children at Indiana University Health, Indianapolis, Indiana
    Run by
    Indiana University
  8. Michigan Healthy Mom (MI-MOM) Pregnancy Improvement Web Application Trial

    The purpose of this research study is to see if using the MI MOM App improves pregnancy and postpartum health. There are two study groups, where one group is "treatment as usual" and the other is the "MI MOM App" group. Both groups will be asked to answer questions about their pregnancy health. Res…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Shiawasee Health Department, Corunna, Michigan
    Locations
    8 in total
    Run by
    Michigan State University
  9. Prenatal Sonographic Prediction of Placental Histology and Function

    The purpose of this two-phase observational study is to investigate the use of ultrasonography to predict placental pathology at the time of delivery.

    Stage
    Not phased
    Ages
    18 to 60
    Site
    NorthShore University HealthSystem, Evanston, Illinois
    Run by
    Endeavor Health
  10. Better Lifestyle Counseling for African American Women During Pregnancy

    The purpose of this randomized controlled trial is to establish the effectiveness of a culturally targeted and individually tailored behavioral intervention to promote maternal glucose metabolism in African American women.

    Stage
    Not phased
    Ages
    18 to 40
    Site
    University of Illinois at Chicago, Chicago, Illinois
    Locations
    2 in total
    Run by
    University of Illinois at Chicago
  11. Delivering HOPE (Helping Women Optimize Prenatal Equity)

    The overarching research question is: "Does the provision of healthy food (Delivering HOPE) during pregnancy reduce the proportion of women who experience excessive gestational weight gain compared with enhanced standard of care (ESoC)?" To answer this question, the investigators will conduct a lar…

    Stage
    Not phased
    Ages
    16 to 44
    Site
    1st Choice Healthcare, Corning, Arkansas
    Locations
    8 in total
    Run by
    University of Arkansas
  12. Navigating Pregnancy and Parenthood With Lyme Disease

    This is a mixed methods study exploring the experiences of pregnancy and parenting among participants with Lyme disease. Eligible participants will have been diagnosed with Lyme disease (LD), post-treatment Lyme disease syndrome (PTLDS), and/or chronic Lyme (CL) either during or before a prior preg…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Children's National Hospital, Washington D.C., District of Columbia
    Run by
    Children's National Research Institute
  13. Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure

    The purpose of this pilot study is to assess the feasibility of longitudinal neurodevelopmental evaluation of fetuses and infants exposed to Lyme disease in utero. Participants with Lyme disease or Post-Treatment Lyme Disease Syndrome (PTLDS) will be recruited during pregnancy. Pregnancies will be …

    Stage
    Not phased
    Ages
    18 and older
    Site
    Children's National Hospital, Washington D.C., District of Columbia
    Run by
    Children's National Research Institute
  14. Feasibility and Acceptability of HCV Treatment in Pregnancy

    Pregnant adults over the age of 18 who are seen in the Washington University obstetrics and gynecology, maternal fetal medicine or infectious diseases clinic or admitted to BJH with hepatitis C virus infection who have a history of past or current drug use Participant Duration: Approximately 1 year…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Barnes Jewish Hospital, St Louis, Missouri
    Locations
    2 in total
    Run by
    Washington University School of Medicine
  15. Placental Imaging Techniques

    The goal of this proof-of-concept, case-control, clinical trial is to evaluate the efficacy of using two newer ultrasound technologies, quantitative ultrasound (QUS) and ultrafast power Doppler imaging (uPDI), to evaluate the health of the placenta, visualize blood flow through the placental vascul…

    Stage
    Not phased
    Ages
    18 to 45
    Site
    Carilion Clinic Maternal Fetal Medicine, Roanoke, Virginia
    Run by
    Carilion Clinic
  16. Sleep Behaviors in Pregnancy

    The researchers would like to know how long pregnant women spend in different positions during the night - and how often women change positions - across pregnancy. The researchers also want to see if the sleep monitor is able to improve sleep behaviors

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Michigan, Ann Arbor, Michigan
    Run by
    University of Michigan
  17. Cardiometabolic Disease and Substrate Metabolism

    This study's primary purpose is to determine the potential relationship between cardiometabolic disease, specifically insulin resistance (HOMA-IR), and maternal lipid oxidation.

    Stage
    Not phased
    Ages
    18 to 45
    Site
    University of Tennessee Graduate School of Medicine, Knoxville, Tennessee
    Run by
    University of Tennessee Graduate School of Medicine
  18. IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy

    This treatment trial evaluates the addition of an anti-tumor necrosis factor-alpha drug, certolizumab, to usual treatment (a heparin agent and low-dose aspirin) in pregnant women with antiphospholipid syndrome (APS) and repeatedly positive tests for lupus anticoagulant (LAC) to determine if this re…

    Stage
    Phase 2
    Ages
    18 to 40
    Site
    Hospital for Special Surgery, New York, New York
    Locations
    3 in total
    Run by
    David Ware Branch
  19. Maternal and Postnatal Outcomes Study (MOS): A Global Observational Registry Assessing the Safety of Elfabrio® in Women With Fabry Disease and Their Infants During Pregnancy and Breastfeeding

    The goal of this observational registry is to evaluate the safety and outcomes of pregnancy and lactation in women with Fabry disease who are exposed to pegunigalsidase alfa within 30 days prior to conception and/or during pregnancy and lactation. The main objectives are to: * Assess pregnancy outc…

    Stage
    Not phased
    Ages
    Any age
    Site
    No physical study sites - Decentralized, web-based registry, Washington D.C., District of Columbia
    Locations
    5 in total
    Run by
    Chiesi Farmaceutici S.p.A.
  20. Hemophilia A Research Program

    This study longitudinally observes the intergenerational (mother-child) continuum in hemophilia A from pregnancy through early childhood. Because the study follows mother-child pairs, the study includes both a maternal cohort and a pediatric cohort. Each cohort has a primary goal: for the mother wi…

    Stage
    Not phased
    Ages
    Any age
    Site
    University of Washington, Seattle, Washington
    Run by
    University of Washington
  21. Glucose Empowerment Through Monitoring and Social Support in Pregnancy

    The purpose of the research is to learn whether wearing a continuous glucose monitor that shows blood glucose levels in real time on a smart phone app and participating in a group chat with other research participants will help participants keep a healthy blood glucose level during pregnancy. High …

    Stage
    Not phased
    Ages
    18 to 45
    Site
    Tufts Medical Center, Boston, Massachusetts
    Run by
    Tufts Medical Center
  22. Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia

    This study's primary purpose is to determine the relationship between aspirin metabolism and markers of metabolic dysfunction among patients at risk for preeclampsia.

    Stage
    Not phased
    Ages
    18 to 45
    Site
    University of Tennessee Medical Center, Knoxville, Tennessee
    Run by
    University of Tennessee Graduate School of Medicine
  23. Relugolix Pregnancy Registry: An Observational Study of the Safety of Relugolix-Containing Therapy Exposure in Pregnant Women and Their Offspring

    The Relugolix Pregnancy Registry is a prospective, observational cohort study designed to evaluate the association between relugolix-containing therapy exposure during pregnancy and subsequent maternal, fetal, and infant outcomes. Data will be collected from enrolled pregnant women and the healthca…

    Stage
    Not phased
    Ages
    0 and older
    Site
    PPD, Wilmington, North Carolina
    Run by
    Sumitomo Pharma Switzerland GmbH
  24. The Heartland Study

    The Heartland Study is a prospective, observational study that will enroll up to 2,600 pregnant participants across the Heartland States in the U.S.. The objective of the Heartland Study is to address major knowledge gaps concerning the health effects of herbicides on maternal and infant health. Th…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Indiana University Medical Center, Indianapolis, Indiana
    Locations
    4 in total
    Run by
    Heartland Health Research Alliance
  25. Impact of Patient Selected Visual Art in the Hospital Room During Antepartum Admission on Hospital Satisfaction Scores and Patient Experience

    The purpose of this study is to assess whether patient-selected visual art for patients admitted to the antepartum unit will increase hospital satisfaction compared to routine care.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Albany Medical Center, Albany, New York
    Run by
    Albany Medical College

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.