Pneumonia Clinical Trials

19 studies are recruiting for pneumonia in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Study of Lung Proteins in Patients With Pneumonia

   This study will examine the different types of proteins present in the lungs of patients with pneumonia to explore the causes of different types of the disease. Pneumonia is a condition that causes lung inflammation AND is often caused by an infection. It is usually diagnosed by lung x-rays and lis…

   Stage

   Not phased

   Ages

   3 to 99

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institutes of Health Clinical Center (CC)

   See if you can join NCT00077909 on ClinicalTrials.gov

2. Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

   The Hyper IgE Syndromes (HIES) are primary immunodeficiencies resulting in eczema and recurrent skin and lung infections. Autosomal dominant Hyper IgE syndrome (AD-HIIES; Job's syndrome) is caused by STAT3 mutations, and is a multi-system disorder with skeletal, vascular, and connective tissue mani…

   Stage

   Not phased

   Ages

   0 to 120

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT00006150 on ClinicalTrials.gov

3. Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment

   This study is designed to measure the correlation of hyperpolarized 129-Xe magnetic resonance imaging (129-XeMRI) in allogeneic hematopoietic cell transplant (allo-HCT) recipients at MD Anderson Cancer Center (MDACC) who develop bronchiolitis obliterans syndrome (BOS) or BOS stage 0p (pulmonary imp…

   Stage

   Not phased

   Ages

   18 and older

   Site

   M D Anderson Cancer Center, Houston, Texas

   Run by

   M.D. Anderson Cancer Center

   See if you can join NCT05041140 on ClinicalTrials.gov

4. Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

   The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK…

   Stage

   Not phased

   Ages

   0 to 20

   Site

   Lucile Packard Children's Hospital, Palo Alto, California

   Locations

   52 in total

   Run by

   Duke University

   See if you can join NCT04278404 on ClinicalTrials.gov

5. How OMT Benefits Newly Diagnosed Patients With Respiratory Illness When Given Alongside Other Standard Care.

   This study is to see Osteopathic Manipulative Therapy, or OMT, can aid in treating patients being seen for respiratory illness and associated symptoms. The hypothesis is that the addition of OMT therapy, alongside other standard care (such as a medication), can help lessen patient symptoms sooner t…

   Stage

   Not phased

   Ages

   65 to 100

   Site

   Geisinger 65-Forward, Buckhorn, Bloomsburg, Pennsylvania

   Run by

   Geisinger Clinic

   See if you can join NCT06495021 on ClinicalTrials.gov

6. The Effects of Endotracheal Suctioning on Pain and Serum Markers

   The goal of this experimental study is to understand if endotracheal tube (ETT) suctioning increases pain and causes stress on the body in intubated adult ICU patients. These patients are already on ventilators, which means they need suctioning to keep their airways clear, but this procedure may be…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Loma Linda University Medical Center Troesh Medical Campus, Loma Linda, California

   Run by

   Loma Linda University

   See if you can join NCT06692400 on ClinicalTrials.gov

7. A Clinical Trial to Evaluate agenT-797 Plus Standard of Care in Participants With Severe Pneumonia With Moderate to Severe Acute Hypoxemic Respiratory Failure

   This clinical trial will evaluate the efficacy and safety of a single intravenous dose of agenT-797 administered in addition to standard of care (SOC), compared with placebo plus SOC, in reducing short-term mortality in adult participants with severe pneumonia and moderate to severe AHRF. All parti…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   First Lviv Territorial Medical Union, Lviv,

   Locations

   4 in total

   Run by

   MiNK Therapeutics

   See if you can join NCT07615010 on ClinicalTrials.gov

8. iNO300 Therapy in Critically Ill Patients With Pneumonia

   The goal of this clinical trial is to learn the formation and recovery rate of methemoglobin (MetHb) in severely sick patients with pneumonia who receive high doses of inhaled nitric oxide (iNO) therapy at 250 parts per million (ppm), not exceeding 300 ppm. Meanwhile, the benefits of the therapy to…

   Stage

   EARLY_Phase 1

   Ages

   18 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT06950294 on ClinicalTrials.gov

9. A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting

   The purpose of this study is to learn about how well the 20-valent pneumococcal conjugate vaccine (20vPnC) works against radiologically-confirmed community-acquired pneumonia (RAD+CAP) due to the 7 new serotypes (types of a bacteria called Streptococcus pneumoniae that cause pneumonia) included in …

   Stage

   Not phased

   Ages

   65 and older

   Site

   El Centro Regional Medical Center, El Centro, California

   Locations

   54 in total

   Run by

   Pfizer

   See if you can join NCT05452941 on ClinicalTrials.gov

10. Lung Ultrasound for Guiding Antibiotic Use in Pediatric Pneumonia

    Pneumonia is a major cause of illness and death in children, with an annual incidence of about 3.3 per 1,000 in those under five years old, many requiring hospitalization. The diagnosis is challenging due to the absence of a universally accepted gold standard, leading to variability in emergency se…

    Stage

    Not phased

    Ages

    3 to 10

    Site

    Yale New Haven Children's Hospital, New Haven, Connecticut

    Locations

    18 in total

    Run by

    Meyer Children's Hospital IRCCS

    See if you can join NCT06921993 on ClinicalTrials.gov

11. Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia.

    A Phase 2a, randomized, double-blind, placebo-controlled, multiple ascending dose study in patients who are hospitalized with presumed pneumonia requiring supplemental oxygen therapy. The purpose of this study is to examine the safety, tolerability and efficacy of AV-001 Injection administration da…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Hoag Memorial Hospital Presbyterian, Newport Beach, California

    Locations

    5 in total

    Run by

    Vasomune Therapeutics, Inc.

    See if you can join NCT05123755 on ClinicalTrials.gov

12. The APS Phenotyping Study

    The goal of the observational APS phenotyping study is to better understand risk factors, potential biomarkers, length and severity of illness, and recovery for adults with ARDS, pneumonia, and/ or sepsis. This study will also generate a biobank of specimens collected from these patients that will …

    Stage

    Not phased

    Ages

    18 and older

    Site

    Fresno Community Hospital and Medical Center, Fresno, California

    Locations

    20 in total

    Run by

    Vanderbilt University Medical Center

    See if you can join NCT06521502 on ClinicalTrials.gov

13. The Role of Circadian Clock Proteins in Innate and Adaptive Immunity

    Our data suggest that modulating the characteristics of light carries the potential to modify the host response to injury and critical illness and thus, improve outcome. The ability to modify the host response to the stress of major operations and sepsis carries immense potential to improve patient…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    Barnes Jewish Hospital, St Louis, Missouri

    Run by

    Washington University School of Medicine

    See if you can join NCT03482245 on ClinicalTrials.gov

14. Performance of New Diagnostic Methods in Older Adults With Pneumonia

    Create a clinical diagnostic pathway for older ED adults with pneumonia and its subgroups (bacterial, viral, and co-infection) and determine whether novel biomarkers improve diagnostic accuracy. The investigators will conduct a prospective observational trial of 250 ED patients ≥65 years old with s…

    Stage

    Not phased

    Ages

    65 and older

    Site

    The Ohio State University, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT06092008 on ClinicalTrials.gov

15. Reducing Overuse of Antibiotics With Decision Support

    Eliminating inappropriate antibiotic use in pediatric lower respiratory tract infections (LRTI) is the central focus of this research. LRTIs (pneumonia, bronchiolitis, and infection-related exacerbations of asthma) account for nearly one-third of all emergency department (ED) visits and 40% of all …

    Stage

    Not phased

    Ages

    0 to 17

    Site

    Monroe Carell Jr Children's Hospital at Vanderbilt, Nashville, Tennessee

    Locations

    3 in total

    Run by

    Vanderbilt University Medical Center

    See if you can join NCT06788093 on ClinicalTrials.gov

16. Follow-up Automatically vs. As-Needed Comparison (FAAN-C) Trial

    Compare the effectiveness of automatic vs as-needed (PRN) post-hospitalization follow-up for children who are hospitalized for common infections.

    Stage

    Not phased

    Ages

    Up to 18

    Site

    Phoenix Children's Hospital, Phoenix, Arizona

    Locations

    14 in total

    Run by

    University of Utah

    See if you can join NCT05471908 on ClinicalTrials.gov

17. PICNIC Study - PatIent Centered aNtIbiotic Courses in Children With Medical Complexity

    To determine if clinicians can safely reduce antibiotic exposure in children with medical complexity (CMC) who are diagnosed with pneumonia by implementing an intervention that bases total antibiotic duration on an individual's clinical stability.

    Stage

    Not phased

    Ages

    2 to 25

    Site

    Boston Children's Hospital, Boston, Massachusetts

    Run by

    Boston Children's Hospital

    See if you can join NCT06364514 on ClinicalTrials.gov

18. Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

    Dynamic digital radiography (DDR) is a new advanced version of chest radiography that captures dynamic images at a rate of 15 frames per second. It is coupled with an analytical software that allows it to provide more advanced measures of lung motion, ventilation, and perfusion compared to traditio…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Brigham and Women's Hospital, Boston, Massachusetts

    Run by

    Brigham and Women's Hospital

    See if you can join NCT06538376 on ClinicalTrials.gov

19. Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control

    The goal of this study is to learn if dental infection control treatment delivered to older adult nursing home residents at their place of residence will result in : * improved dental health * reduced risk of pneumonia * better glucose control for diabetic patients compared to the pre-project denta…

    Stage

    Not phased

    Ages

    60 to 100

    Site

    Office of Dental Health, Department of Health and Senior Services, Jefferson City, Missouri

    Run by

    Missouri Department of Health and Senior Services

    See if you can join NCT06890676 on ClinicalTrials.gov