Physical Inactivity Clinical Trials

24 studies are recruiting for physical inactivity in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Actívatexto: Advancing Smoking Cessation and Physical Activity Among Latinos

   The purpose of this randomized controlled trial is to assess the efficacy of Actívatexto (Aim 1) and the mediators of the presumed treatment effect (Aim 2) among Latino adults who smoke. Actívatexto is a mobile intervention that integrates four components: 1) a text messaging program that promotes …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Rochester Medical Center, Rochester, New York

   Run by

   University of Rochester

   See if you can join NCT06926608 on ClinicalTrials.gov

2. Optimization of a Behavioral Intervention to Increase Physical Activity in Older Adults Living With HIV

   The goal of this clinical trial is to examine 3 interventions designed to increase physical activity in older adults with HIV. We will examine 3 potential components of an intervention package: physical activity coaching, cognitive behavioral therapy targeted toward common barriers to physical acti…

   Stage

   Not phased

   Ages

   50 and older

   Site

   Hennepin Healthcare Research Institute, Minneapolis, Minnesota

   Locations

   2 in total

   Run by

   Butler Hospital

   See if you can join NCT05752500 on ClinicalTrials.gov

3. Motivating Activity Through Text Communications - Helping Adults Increase Movement

   The goal of this clinical trial is to compare the effect of different types of text messages on physical activity levels of middle-aged and older adults and to determine whether these messages are effective in adults age 40 and older who are engaging in less than 90 minutes per week of moderate or …

   Stage

   Not phased

   Ages

   40 and older

   Site

   University of Michigan, Ann Arbor, Michigan

   Run by

   University of Michigan

   See if you can join NCT07593677 on ClinicalTrials.gov

4. Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM

   Women with a history of gestational diabetes mellitus (GDM) are at a 2-fold greater risk for the development of overt cardiovascular disease (CVD) following the effected pregnancy. While subsequent development of type II diabetes elevates this risk, prior GDM is an independent risk factor for CVD m…

   Stage

   EARLY_Phase 1

   Ages

   18 to 50

   Site

   University of Iowa, Iowa City, Iowa

   Run by

   Anna Stanhewicz, PhD

   See if you can join NCT06547619 on ClinicalTrials.gov

5. Exercise Snacking and Cardiometabolic Health

   Regular physical activity is associated with numerous health benefits, yet many young adults do not achieve recommended levels of physical activity. Exercise snacking, which involves performing brief bouts of physical activity throughout the day, may provide a practical alternative to traditional e…

   Stage

   Not phased

   Ages

   18 to 60

   Site

   University of Wisconsin-River Falls, River Falls, Wisconsin

   Run by

   University of Wisconsin, River Falls

   See if you can join NCT07718113 on ClinicalTrials.gov

6. Promoting Physical Activity in Older Hispanic/Latino(a) Adults

   In this randomized controlled trial, study staff will randomize 130 Hispanic/Latino adults without dementia and over age 55 from Southern California and from Kaiser Permanente Washington (State) to either the culturally adapted De Pie physical activity intervention or an active comparison program f…

   Stage

   Not phased

   Ages

   55 to 89

   Site

   University of California San Diego, San Diego, California

   Locations

   2 in total

   Run by

   Kaiser Permanente

   See if you can join NCT06362824 on ClinicalTrials.gov

7. Smart Walk: A Culturally Tailored Smartphone-Delivered Physical Activity Intervention for African American Women

   The purpose of this study is to test a culturally tailored, smartphone-delivered intervention designed to increase physical activity and reduce risk for heart disease and type 2 diabetes among African American women.

   Stage

   Phase 2

   Ages

   24 to 65

   Site

   Arizona State University, Phoenix, Arizona

   Run by

   Arizona State University

   See if you can join NCT06337708 on ClinicalTrials.gov

8. Evaluating Health Outcomes of AI-Based Fitness Wearables and App Programs in Older Adults Living Alone With Cognitive Decline

   The overarching goal of our research is to develop personalized and accessible healthy aging lifestyle interventions aimed at promoting physical activity (PA) and improving health among community-dwelling older adults living alone with cognitive decline (LACD). To achieve this goal, the purpose of …

   Stage

   Not phased

   Ages

   65 and older

   Site

   The University of Tennessee, Knoxville. Health, Recreation, and Physical Education Building, Knoxville, Tennessee

   Locations

   2 in total

   Run by

   The University of Tennessee, Knoxville

   See if you can join NCT07207993 on ClinicalTrials.gov

9. Be Well at Work-Plus: A Depression and Physical Activity Intervention for Hospital Service Workers (Aim 2)

   This study develops and tests a dynamic workplace-based depression intervention that is tailored to the specific social and behavioral needs of low-wage hospital service workers. The intervention involves assessment of depression-related work impairment, work-focused cognitive behavioral therapy, w…

   Stage

   Not phased

   Ages

   18 and older

   Site

   San Diego State University, San Diego, California

   Run by

   San Diego State University

   See if you can join NCT06753123 on ClinicalTrials.gov

10. Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors

    The goal of this clinical trial is to improve cancer patient's health, survival, and quality of life by dispelling risk behaviors for Northwestern Memorial Health Care (NMHC) patients who are cancer survivors. The main question[s] STELLAR aims to answer are: * How best to combine three behavior int…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Northwestern University-Feinberg School of Medicine, Chicago, Illinois

    Run by

    Northwestern University

    See if you can join NCT05687604 on ClinicalTrials.gov

11. Positive Emotions Following Acute Cardiac Events

    The focus of this study is to test the efficacy of a 12-week, remotely delivered, positive-psychology-motivational interviewing (PP-MI) intervention, with additional twice weekly text messages for a total of 24 weeks (with interactive, algorithm-driven, goal-focused text messages in the final 12 we…

    Stage

    Not phased

    Ages

    18 to 95

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT05412862 on ClinicalTrials.gov

12. Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health

    Competitive sport increases risk for musculoskeletal injury (e.g., traumatic knee injury) and may position former athletes for early onset of chronic diseases, chronic pain, poor health-related quality of life, and disability. Quantifying function in former athletes with and without a prior injury …

    Stage

    Not phased

    Ages

    18 to 64

    Site

    Marquette University, Milwaukee, Wisconsin

    Run by

    Marquette University

    See if you can join NCT05344001 on ClinicalTrials.gov

13. Pilot-Testing Real-Time Engagement for Learning to Effectively Control Type 2 Diabetes

    The goal of this study is to pilot test features of a new smartphone app and to gather feedback related to wearing a continuous glucose monitor (CGM) and a Fitbit device, as well as to obtain input on health behavior-focused messages delivered through the app. The study will enroll English-speaking…

    Stage

    Not phased

    Ages

    16 to 24

    Site

    Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania

    Run by

    University of Pittsburgh

    See if you can join NCT07270016 on ClinicalTrials.gov

14. Impact of Dietary Phosphate Excess on Exercise Capacity and Visceral Adiposity

    Studies in mice demonstrated that dietary phosphate (Pi) loading that mimic the level of US adult consumption leads to reduced spontaneous locomotor activity, exercise capacity, and reduced resting metabolic rate when in normal mice by impairing skeletal muscle mitochondrial function and fat oxidat…

    Stage

    Not phased

    Ages

    18 to 80

    Site

    University of Texas Southwestern, Dallas, Texas

    Run by

    University of Texas Southwestern Medical Center

    See if you can join NCT05147909 on ClinicalTrials.gov

15. Activating SilverSneakers Benefits for Seniors With Osteoarthritis

    The aim of this pragmatic randomized controlled trial is to test the effects of a brief proactive care intervention involving mailed material and two phone calls on: (1) increasing participation in SilverSneakers exercise programs among older adults with osteoarthritis; (2) improving physical, soci…

    Stage

    Not phased

    Ages

    65 and older

    Site

    Penn State College of Medicine, Hershey, Pennsylvania

    Run by

    Milton S. Hershey Medical Center

    See if you can join NCT06782347 on ClinicalTrials.gov

16. Cognitive Control to Boost Physical Activity Adherence

    This trial is designed to develop and test the efficacy of cognitive training strategies to improve self-regulatory capacities for middle-aged adults to adopt and sustain a physically active lifestyle. The main questions it aims to answer are: * Can cognitive training designed to improve cognitive …

    Stage

    Not phased

    Ages

    40 to 65

    Site

    Psychological and Brain Sciences Building, Iowa City, Iowa

    Locations

    2 in total

    Run by

    University of Iowa

    See if you can join NCT06338774 on ClinicalTrials.gov

17. Free Time For Wellness 2+

    Physical inactivity is pervasive and prevalent in the United States, particularly among women of low socioeconomic position, and women with children. Structural and social barriers make active leisure time a rare commodity creating a pressing health issue because physical inactivity increases the r…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Highbridge Park, New York, New York

    Locations

    10 in total

    Run by

    Columbia University

    See if you can join NCT06654843 on ClinicalTrials.gov

18. COVID-19 Health Adjustments in Nutrition, General Wellness, and Exercise

    The purpose of this study is to find out whether the COVID pandemic has affected participants' current physical activity, fitness, blood pressure, sleep, and mental stress to better understand its long-term health effects. To complete this study, participants will visit the Neurovascular Physiology…

    Stage

    Not phased

    Ages

    18 to 75

    Site

    Indiana University School of Public Health, Bloomington, Indiana

    Run by

    Indiana University

    See if you can join NCT07128095 on ClinicalTrials.gov

19. Black Impact: The Mechanisms Underlying Psychosocial Stress Reduction in a Cardiovascular Health Intervention

    Lower attainment of cardiovascular health (CVH), indicated by the American Heart Association's Life's Simple 7 (LS7; physical activity, diet, cholesterol, blood pressure, body mass index, smoking, glycemia) and Life's Essential 8 (LE8; LS7+sleep) metrics, is a major contributor to Black men having …

    Stage

    Not phased

    Ages

    18 and older

    Site

    The Ohio State University, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT06055036 on ClinicalTrials.gov

20. eMOTION: Examining Affective Mechanisms in Physical Activity Engagement

    This early-phase trial will test intervention strategies to influence affective mechanisms underlying physical activity and determine whether changes in those mechanisms result in change in physical activity behavior among inactive adults who are overweight or obese.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Southern California, Los Angeles, California

    Run by

    University of Southern California

    See if you can join NCT06570642 on ClinicalTrials.gov

21. Using Augmented Reality to Promote Physical Activity in Children With Cerebral Palsy

    Children with cerebral palsy (CP), Gross Motor Functional Classification Scale (GMFCS) I-II will be recruited to participate in a home based physical activity intervention for 4 weeks. Demographic data will be collected, and validated surveys assessing baseline physical activity level and mobility …

    Stage

    Not phased

    Ages

    5 to 18

    Site

    Jackie and Gene Autry Orthopedic Center, CHLA, Los Angeles, California

    Run by

    Children's Hospital Los Angeles

    See if you can join NCT06096272 on ClinicalTrials.gov

22. InMotion - Telehealth Delivered Exercise Promotion to Treat Major Depression After TBI

    The purpose of this randomized controlled trial is to evaluate whether the InMotion intervention, delivered via telehealth (using a HIPAA-compliant video platform or phone), which uses evidence-based behavioral and motivational counseling to increase daily physical activity, is an effective treatme…

    Stage

    Not phased

    Ages

    18 to 64

    Site

    University of Washington Medical Center, Seattle, Washington

    Run by

    University of Washington

    See if you can join NCT06005194 on ClinicalTrials.gov

23. A Pilot Factorial Trial of an Integrated Lifestyle Intervention

    This study plans to learn more about the feasibility and acceptability of integrating the Move physical activity support program within an existing lifestyle intervention program.

    Stage

    Not phased

    Ages

    18 to 65

    Site

    University of Colorado Anschutz Medical Campus, Aurora, Colorado

    Run by

    University of Colorado, Denver

    See if you can join NCT06116435 on ClinicalTrials.gov

24. Increasing Physical Activity for Adults With Multiple Sclerosis (MS)

    This study aims to advance the scientific understanding and potential future implementation of physical activity promotion by testing the efficacy of a phone-based app for increasing activity in insufficiently active patients with multiple sclerosis (MS).

    Stage

    Not phased

    Ages

    18 and older

    Site

    UW Medicine, Seattle, Washington

    Run by

    University of Washington

    See if you can join NCT06270641 on ClinicalTrials.gov