PARKINSON DISEASE (Disorder) Clinical Trials

15 studies are recruiting for parkinson disease (disorder) in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Treatment of Cognitive and Sensorimotor Deficits in Parkinson's Disease With High Definition Transcranial Direct Current Stimulation

   The purpose of this research study is to examine the effects of transcranial Direct Current Stimulation (tDCS) on verbal retrieval and cognition and sensorimotor control and to determine if tDCS can be used as a way to improve retrieval, sensory, and motor abilities in individuals with Parkinson's …

   Stage

   Not phased

   Ages

   50 to 90

   Site

   Callier Clinical Center, The University of Texas at Dallas, Richardson, Texas

   Run by

   The University of Texas at Dallas

   See if you can join NCT07534397 on ClinicalTrials.gov

2. A Study to Evaluate the Efficacy, PK, Safety, and Tolerability of VIM0423 in Adults With Parkinson's Disease Tremor Insufficiently Responsive to Dopaminergic Therapy

   Vista PD is a randomized, placebo-controlled, multicenter study to evaluate the efficacy, PK, safety, and tolerability of VIM0423 in adults with Parkinson's disease tremor insufficiently responsive to dopaminergic therapy. The main objectives of this clinical trial are to determine the following: *…

   Stage

   Phase 2

   Ages

   18 to 65

   Site

   Vima Site #002, Farmington Hills, Michigan

   Locations

   30 in total

   Run by

   Vima Therapeutics

   See if you can join NCT07804615 on ClinicalTrials.gov

3. Optimizing Adaptive DBS for Parkinson's Disease

   Parkinson's disease (PD) affects more than 10 million people worldwide and causes progressive motor symptoms such as slowness, stiffness and tremor. For patients whose symptoms are no longer adequately controlled with medication, deep brain stimulation (DBS) can substantially improve motor function…

   Stage

   Not phased

   Ages

   18 and older

   Site

   UC Davis Center for Neuroscience, Davis, California

   Run by

   University of California, Davis

   See if you can join NCT07798271 on ClinicalTrials.gov

4. GBPDC: Gut-Brain in PD Consortium Master Protocol

   The purpose of this research study is to identify the role that the gut-brain axis, the group of nerves that connect the brain and gut, plays in Parkinson's disease (PD). The National Institute of Diabetes and Digestive and Kidney Diseases is sponsoring this research study. During this study, speci…

   Stage

   Not phased

   Ages

   21 to 80

   Site

   Stanford University, Stanford, California

   Locations

   7 in total

   Run by

   Duke University

   See if you can join NCT07567794 on ClinicalTrials.gov

5. Multicontext Approach for Cognitive Function in Parkinson Disease

   Mild cognitive decline is common in early Parkinson disease (PD) and is associated with disability, reduced quality of life (QOL), and increased risk for dementia. Medical treatments for PD do not prevent or treat cognitive decline and may even exacerbate the problem. Unfortunately, existing cognit…

   Stage

   Not phased

   Ages

   50 and older

   Site

   Washington University School of Medicine, St Louis, Missouri

   Run by

   Washington University School of Medicine

   See if you can join NCT07190404 on ClinicalTrials.gov

6. Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

   The purpose of this study is to find out whether a type of gentle nerve stimulation, called transcutaneous auricular Vagus Nerve Stimulation (taVNS), can help improve how the body regulates heart rate and blood pressure in people with Parkinson's Disease (PD). Problems with heart rate and blood pre…

   Stage

   Phase 1

   Ages

   18 to 80

   Site

   Wellness, Health and Research Facility at UAB, Birmingham, Alabama

   Run by

   University of Alabama at Birmingham

   See if you can join NCT07557706 on ClinicalTrials.gov

7. Effects of Accelerated rTMS On Motor and Cognitive Function in Parkinson's Disease

   Parkinson's disease (PD) is a brain disorder that causes progressive problems with movement, such as slowness, stiffness, tremor, and difficulty walking. Many people with PD also develop problems with thinking and memory. Current medications can help control movement symptoms but often become less …

   Stage

   Not phased

   Ages

   50 to 90

   Site

   San Francisco Neurology and Sleep Center, San Francisco, California

   Run by

   San Francisco Neurology and Sleep Center

   See if you can join NCT07554833 on ClinicalTrials.gov

8. SAD Study in Patients With Parkinson's Disease and Motor Fluctuations

   This is a randomized, placebo-controlled, single ascending dose (SAD) study of SER-252 in participants with Parkinson's Disease (PD) and motor fluctuations.

   Stage

   Phase 1

   Ages

   40 to 80

   Site

   Velocity Clinical Research, Hallandale, Florida

   Locations

   6 in total

   Run by

   Serina Therapeutics

   See if you can join NCT07422675 on ClinicalTrials.gov

9. Adapting rHIRE and Sleep Monitoring in Parkinson's Disease

   Exercise is a primary intervention for symptom management in Parkinson's Disease (PD). However, challenges related to transportation, mobility, and socioeconomic factors often hinder consistent participation in exercise programs. To promote increased access and participation, remote exercise progra…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Colorado Anschutz Medical Campus, Aurora, Colorado

   Run by

   University of Colorado, Denver

   See if you can join NCT07498296 on ClinicalTrials.gov

10. Effects of an Independent Walking Program With Walking Poles in People With Parkinson Disease

    Study Purpose: The purpose of the study is to compare changes in walking in people with Parkinson disease after an 8-week independent walking program with or without using walking poles. Major parts of the Study: Before the walking program: Measurements will be taken of you while you are walking. Y…

    Stage

    Not phased

    Ages

    Any age

    Site

    East Tennessee State University, Johnson City, Tennessee

    Run by

    East Tennessee State University

    See if you can join NCT07551661 on ClinicalTrials.gov

11. Steady Together Fall Prevention Program in the Home

    The purpose of the research study is to assess the efficacy of the occupational therapy Steady Together Fall Prevention Program in the Home for persons with Parkinson's Disease (PwP) who are members of InMotion. InMotion is a community wellness center that offers a variety of programs for PwP. The …

    Stage

    Not phased

    Ages

    18 and older

    Site

    InMotion Wellness Center, Beachwood, Ohio

    Run by

    Cleveland State University

    See if you can join NCT07519096 on ClinicalTrials.gov

12. Effects of Vagal Nerve Stimulation on Leg Muscle Activity and Posture in Parkinson's Disease

    This study is designed to better understand the mechanisms contributing to impaired activation of leg muscles in people with Parkinson's disease (PD) and to test if stimulation of a nerve at the neck can improve muscle activation, walking and balance.

    Stage

    Not phased

    Ages

    21 to 76

    Site

    Movement Disorders Laboratory, Minneapolis, Minnesota

    Run by

    University of Minnesota

    See if you can join NCT07226284 on ClinicalTrials.gov

13. Colonoscopic Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis

    The goal of this observational study is to learn whether tissue samples taken from the colon during routine colonoscopy can detect signs of Parkinson's disease. The main question it aims to answer is: Can doctors find a protein called alpha-synuclein in colon tissue samples from people with Parkins…

    Stage

    Not phased

    Ages

    40 to 99

    Site

    Oregon Health & Science University, Portland, Oregon

    Run by

    CND Life Sciences

    See if you can join NCT07204652 on ClinicalTrials.gov

14. Colonic Tissue Biopsy Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis or REM Sleep Behavior Disorder

    The goal of this observational study is to learn whether tissue samples taken from the colon during routine colonoscopy can detect signs of Parkinson's disease or REM Sleep Behavior Disorder (RBD). The main question it aims to answer is: Can doctors find a protein called alpha-synuclein in colon ti…

    Stage

    Not phased

    Ages

    40 to 99

    Site

    Digestive Disease Associates, Branford, Connecticut

    Run by

    CND Life Sciences

    See if you can join NCT07217054 on ClinicalTrials.gov

15. Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms

    This study tests a new, non-invasive brain stimulation device called Sphere V3.0 to help improve movement problems in people with Parkinson's disease. The device delivers gentle electrical signals to the scalp using small electrodes placed on the head. Participants will use the device at home for 1…

    Stage

    Phase 1

    Ages

    18 to 80

    Site

    U LLC Headquarters, Cleveland, Ohio

    Run by

    U: The Mind Company

    See if you can join NCT07182058 on ClinicalTrials.gov