Pancreatic Ductal Adenocarcinoma (PDAC) Clinical Trials in Baltimore, Maryland

7 studies are recruiting for pancreatic ductal adenocarcinoma (pdac) in Baltimore, Maryland right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

    The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of RMC-5127 as a monotherapy and in combination with either daraxonrasib or cetuximab in adults with KRAS G12V-mutant solid tumors.

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Johns Hopkins, Baltimore, Maryland
    Locations
    9 in total
    Run by
    Revolution Medicines, Inc.
  2. Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

    The purpose of this study is to evaluate the safety and efficacy of an investigational RAS(ON) inhibitor administered as monotherapy or in combination with chemotherapy, compared with standard of care (SOC) chemotherapy alone.

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
    Locations
    49 in total
    Run by
    Revolution Medicines, Inc.
  3. Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

    The purpose of this study is to evaluate the efficacy of an investigational RAS(ON) inhibitor administered in combination with chemotherapy compared to placebo in combination with chemotherapy.

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Johns Hopkins University, Baltimore, Maryland
    Locations
    9 in total
    Run by
    Revolution Medicines, Inc.
  4. A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

    This study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab in patients with metastatic KRAS G12D - mutated Pancreatic Cancer

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Johns Hopkins University, Baltimore, Maryland
    Locations
    29 in total
    Run by
    Verastem, Inc.
  5. Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

    This study is to evaluate the safety and tolerability of RMC-9805 as monotherapy and in combination with RMC-6236 in adults with KRAS G12D-mutant solid tumors.

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Johns Hopkins University, Baltimore, Maryland
    Locations
    17 in total
    Run by
    Revolution Medicines, Inc.
  6. A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

    The purpose of this study is to evaluate the safety, tolerability, and efficacy of BMS-986523 alone and in combination with anti-cancer agents in participants with advanced solid malignancies

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Johns Hopkins Hospital, Baltimore, Maryland
    Locations
    8 in total
    Run by
    Bristol-Myers Squibb
  7. Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

    Evaluate the safety and tolerability of RMC-6236 in adults with specific RAS mutant advanced solid tumors.

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Johns Hopkins University, Baltimore, Maryland
    Locations
    21 in total
    Run by
    Revolution Medicines, Inc.

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.