Pancreatic Cancer Clinical Trials

116 studies are recruiting for pancreatic cancer in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 5

1. EUS RFA for Treatment of Pancreatic Ductal Adenocarcinoma (PDAC)

   This is a single arm study in the treatment of pancreatic ductal adenocarcinoma (PDAC). The investigators propose to test the tolerability of chemotherapy plus endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) using the RF Electrode in patients receiving palliative second or third line…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Tisch Hospital, New York, New York

   Run by

   NYU Langone Health

   See if you can join NCT05723107 on ClinicalTrials.gov

2. Pancreatic Adenocarcinoma Gene Environment Risk Study

   After informed consent, participants will be asked to complete a medical/family history questionnaire and provide a blood sample. Some participants may also be asked to provide a urine sample. Individuals undergoing procedures that require collection of biological samples for clinical purposes may …

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Pittsburgh, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT00912717 on ClinicalTrials.gov

3. Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow

   Patients with resectable solid primary cancers and even limited number of metastases are potentially curable. However, most patients develop recurrences despite surgery. Also, early detection of lung cancer with low dose CT screening may cure patients at an early stage. Circulating and disseminated…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Harry S Truman Veterans Memorial Hospital, Columbia, Missouri

   Run by

   University of Missouri-Columbia

   See if you can join NCT03551951 on ClinicalTrials.gov

4. UCSF PANC Cyst Registry

   Pancreatic cysts are found incidentally on 15-50% of CT and MRIs for all indications and their prevalence is increasing. Many of these cysts may be precursors to pancreatic cancer, and thus pose a substantial risk, however, the vast majority are benign. Increased detection of pancreatic cysts provi…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California, San Francisco, San Francisco, California

   Run by

   University of California, San Francisco

   See if you can join NCT04291651 on ClinicalTrials.gov

5. Proton Radiation for Unresectable, Borderline Resectable, or Medically Inoperable Carcinoma of the Pancreas

   The prognosis for patients with localized pancreatic adenocarcinoma who are not surgical candidates is poor. Patients characterized as having "borderline resectable" disease treated with preoperative chemo-radiotherapy fair somewhat better - although many of these patients are not converted to rese…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Northwestern Medicine Chicago Proton Center, Warrenville, Illinois

   Locations

   4 in total

   Run by

   Proton Collaborative Group

   See if you can join NCT02598349 on ClinicalTrials.gov

6. 64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer

   This is a multicenter, open-label, prospective Phase 1/2a study to assess safety and tolerability, establish dosimetry and to identify an optimal imaging dose (radioactivity) and imaging time window of 64Cu-LNTH-1363S, and to compare its imaging biodistribution with FAP expression by IHC in patient…

   Stage

   Phase 1

   Ages

   15 and older

   Site

   City of Hope, Duarte, California

   Locations

   5 in total

   Run by

   Lantheus Medical Imaging

   See if you can join NCT06298916 on ClinicalTrials.gov

7. APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

   To assess: * efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification, solid tumors harboring MET amplification, solid tumors harboring MET fusion, primary CNS tumors harboring MET alterations, solid tumors harboring w…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Cedars-Sinai Medical Center - Samuel Oschin Comprehensive Cancer Institute, Los Angeles, California

   Locations

   35 in total

   Run by

   Apollomics Inc.

   See if you can join NCT03175224 on ClinicalTrials.gov

8. Chemo4METPANC Combination Chemokine Inhibitor, Immunotherapy, and Chemotherapy in Pancreatic Adenocarcinoma

   The purpose of this study is to determine if combination treatment with cemiplimab, motixafortide, gemcitabine, and nab-paclitaxel is effective in decreasing the size of the tumor(s), if it will prolong life in patients, and if it's safe. The treatment consists of standard chemotherapy (gemcitabine…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Columbia University Irving Medical Center, New York, New York

   Locations

   3 in total

   Run by

   Gulam Manji

   See if you can join NCT04543071 on ClinicalTrials.gov

9. Initial Feasibility Study to Treat Borderline Resectable Pancreatic Cancer With a Planar LDR Source

   Initial study to evaluate local control and the preferred method of attachment of the CivaSheet in the setting of suspected close or positive margins at the time of surgical tumor removal.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Advocate Christ Medical Center, Oak Lawn, Illinois

   Locations

   6 in total

   Run by

   CivaTech Oncology

   See if you can join NCT02843945 on ClinicalTrials.gov

10. Artificial Intelligence in Endoscopic Ultrasound

    The objective of the study is to determine if this artificial intelligence system is capable of detecting abnormalities in the pancreas that are identified by an endoscopist at endoscopic ultrasound procedures.

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Orlando Health, Orlando, Florida

    Run by

    Orlando Health, Inc.

    See if you can join NCT06564571 on ClinicalTrials.gov

11. A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

    ATLAS-101 is a Phase I/II clinical trial of AMXI-5001 in adult participants with advanced malignancies who have previously failed other therapies. The study has two phases. The purpose of Phase I (Dose Escalation) is to confirm the appropriate treatment dose and Phase II (Dose Expansion) is to char…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    University of California, Los Angles (UCLA) Department of Medicine - Hematology/Oncology, Los Angeles, California

    Locations

    4 in total

    Run by

    AtlasMedx, Incorporated

    See if you can join NCT04503265 on ClinicalTrials.gov

12. Study of Amplitude-Modulated Radiofrequency Electromagnetic Fields in Metastatic Pancreatic Cancer

    The objective of this research is to find out what effects (good and bad), the combination of gemcitabine and nab-paclitaxel therapy (GEM-ABR for the rest of the document), standard chemotherapy for pancreatic cancer, and the TheraBionic device has on participants' condition.

    Stage

    Phase 2

    Ages

    18 and older

    Site

    Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina

    Run by

    THERABIONIC INC.

    See if you can join NCT05776524 on ClinicalTrials.gov

13. American Hepato-Pancreato-Biliary Association (AHPBA) Pancreatic Irreversible Electroporation (IRE) Registry

    The purpose of this study is to create a registry to provide insight into treatment selection and treatment outcome of pancreatic IRE in order to develop an evidence base such that physicians can provide the best possible care to patients with pancreatic cancer requiring surgical interventions. The…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Alabama Birmingham, Birmingham, Alabama

    Locations

    16 in total

    Run by

    University of Louisville

    See if you can join NCT02674100 on ClinicalTrials.gov

14. Onvansertib in Combination With NALIRIFOX for First Line Treatment of Advanced Pancreatic Cancer

    Pancreatic cancer is a deadly disease and will be the second leading cause of cancer related death behind lung cancer by 2030. Over 62,000 people are diagnosed each year in the United States with about 90% succumbing to the disease within 5 years. In the metastatic setting, NALIRIFOX, FOLFIRINOX an…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    The University of Kansas Cancer Center, Westwood Campus, Kansas City, Kansas

    Run by

    University of Kansas Medical Center

    See if you can join NCT06736717 on ClinicalTrials.gov

15. Modulation of the Gut Microbiome With Pembrolizumab Following Chemotherapy in Resectable Pancreatic Cancer

    A multi-institutional, single arm pilot study of antibiotics and pembrolizumab, following chemotherapy for the treatment of surgically resectable pancreatic cancer.

    Stage

    Phase 2

    Ages

    19 and older

    Site

    Icahn School of Medicine at Mount Sinai, New York, New York

    Run by

    Icahn School of Medicine at Mount Sinai

    See if you can join NCT05462496 on ClinicalTrials.gov

16. EUS Examination Using EndoSound Vision System vs. Standard Echoendoscope

    This is a randomized trial to compare the standard echoendoscope with the newly developed EndoSound Visual System in the evaluation of lesions in the gastrointestinal tract.

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Orlando Health, Orlando, Florida

    Run by

    Orlando Health, Inc.

    See if you can join NCT06340620 on ClinicalTrials.gov