Overactive Bladder Clinical Trials

19 studies are recruiting for overactive bladder in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Sacral Neuromodulation for Male Overactive Bladder (MOAB)

   To assess the post-market clinical outcomes of the Axonics SNM System for treatment of overactive bladder in male patients.

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   23 in total

   Run by

   Axonics, Inc.

   See if you can join NCT06511141 on ClinicalTrials.gov

2. Flyte Device for Improving Urinary Incontinence Among Endometrial and Cervical Cancer Survivors Who Have Undergone Radiation Therapy

   This clinical trial studies how well and how easy it is to use a device called Flyte in improving problems with bladder control (urinary incontinence) among endometrial and cervical cancer survivors who have undergone radiation therapy. Urinary incontinence is common after pelvic radiation therapy …

   Stage

   Not phased

   Ages

   21 and older

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT07662824 on ClinicalTrials.gov

3. Self-Start Triage Model for Post-Botox® Lower Urinary Tract Symptoms

   The primary objective of this study is to investigate whether providing a standing, take-home prescription for empiric Macrobid (self-start model) is superior to standard call-in/urgent care triage (triage model) among patients undergoing intradetrusor Botox®. Urinary tract infections. (UTIs) are t…

   Stage

   EARLY_Phase 1

   Ages

   18 and older

   Site

   Cleveland Clinic, Cleveland, Ohio

   Run by

   The Cleveland Clinic

   See if you can join NCT07648290 on ClinicalTrials.gov

4. BTL Emsella Chair Versus Sham for the Treatment of Overactive Bladder

   The purpose of this clinical trial is to compare the Emsella Chair therapy to Sham and to determine whether electromagnetic technology is effective in the treatment of overactive bladder (OAB). Currently there are no other studies utilizing the Emsella Chair for the treatment of OAB. Eligible subje…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Corewell Health William Beaumont University Hospital, Royal Oak, Michigan

   Run by

   Corewell Health East

   See if you can join NCT04873037 on ClinicalTrials.gov

5. Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms

   The objective of our multi-center randomized single-blind study is to examine the safety and effect of intra-detrusor OnabotulinumtoxinA injections at the time of holium laser enucleation of the prostate (HoLEP) in men with overactive bladder symptoms with and without urge incontinence.

   Stage

   Phase 2

   Ages

   18 to 89

   Site

   Northwestern Medicine, Chicago, Illinois

   Run by

   Northwestern University

   See if you can join NCT05878951 on ClinicalTrials.gov

6. Add-On ZIDA Sock Therapy for Overactive Bladder

   Many people with overactive bladder (OAB) continue to experience symptoms despite pharmacologic treatment. This study evaluates the use of the ZIDA Control Sock, an FDA-cleared, noninvasive wearable device that delivers mild electrical stimulation near the ankle, as an adjunct to usual care. Adults…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Rutledge Tower at Medical University of South Carolina, Charleston, South Carolina

   Run by

   Medical University of South Carolina

   See if you can join NCT07432659 on ClinicalTrials.gov

7. Noninvasive Ultrasound Assessment of Detrusor Dysfunction

   The purpose of this study is to test a new ultrasound method called Quantitative Ultrasound Bladder Vibrometry to detect abnormal bladder function.

   Stage

   Not phased

   Ages

   18 to 90

   Site

   Mayo Clinic, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT05652023 on ClinicalTrials.gov

8. Neuromodulating Cortical Regions Involved in Neurogenic Bladder in MS

   Neurogenic overactive bladder (NOAB), characterized by urinary frequency, urgency or urgency incontinence symptoms occurring during the storage phase of the bladder, is the most common urinary complaint in multiple sclerosis (MS). Current management options for NOAB in MS have limited efficacy and …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Houston Methodist Hospital, Houston, Texas

   Run by

   The Methodist Hospital Research Institute

   See if you can join NCT06072703 on ClinicalTrials.gov

9. Fluoroscopy Radiation Reduction During Sacral Neuromodulation Lead Placement

   Fluoroscopy is performed when placing a lead during a sacral neuromodulation procedure. During lead placement, subjects will receive either conventional or experimental fluoroscopic settings. The radiation exposure will be compared between the two groups.

   Stage

   Not phased

   Ages

   18 to 89

   Site

   Loma Linda University Health, Loma Linda, California

   Run by

   Loma Linda University

   See if you can join NCT04527445 on ClinicalTrials.gov

10. TReating Incontinence for Underlying Mental and Physical Health

    The TRIUMPH study is a randomized, double-blinded, 3-arm, parallel-group trial designed to compare the effects of anticholinergic bladder therapy versus a) beta-3-adrenergic agonist bladder therapy and b) no bladder pharmacotherapy on cognitive, urinary, and other aging-related functional outcomes …

    Stage

    Phase 4

    Ages

    60 and older

    Site

    Stanford University, Palo Alto, California

    Locations

    2 in total

    Run by

    University of California, San Francisco

    See if you can join NCT05362292 on ClinicalTrials.gov

11. Pelvic Health Electrically Evoked Recording (PEER) 2 Study

    To collect physiological signals at several timepoints during the therapy evaluation period.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Indiana University Health Methodist Research Institute, Indianapolis, Indiana

    Locations

    7 in total

    Run by

    MedtronicNeuro

    See if you can join NCT05200923 on ClinicalTrials.gov

12. Percutaneous Nerve Evaluation Trial Time

    Sacral neuromodulation (SNM) was approved by the Food and Drug Administration (FDA) for the treatment of urgency incontinence (UUI) in 1998. One of two trial phase techniques are utilized prior to placement of the implantable pulse generator (IPG) to predict a patient's success with the device: a p…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Chicago, Chicago, Illinois

    Run by

    University of Chicago

    See if you can join NCT06226220 on ClinicalTrials.gov

13. Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women

    The goal of this clinical trial is to learn if a vaginal radiofrequency (RF) device called MORPHEUSV works to treat overactive bladder (OAB) in women. Researchers also want to learn how safe the device is for this indication. This study will include women ages 22 to 80 who have had OAB symptoms for…

    Stage

    Not phased

    Ages

    22 to 80

    Site

    Advanced Specialty Research, Boise, Idaho

    Locations

    9 in total

    Run by

    InMode MD Ltd.

    See if you can join NCT07209397 on ClinicalTrials.gov

14. A Real World Study of eCoin for Urgency Urinary Incontinence: Post Approval Evaluation (RECIPE)

    A prospective, multicenter, single-arm study to evaluate the safety and effectiveness of the eCoin® implanted tibial nerve stimulator in subjects with urgency urinary incontinence (UUI).

    Stage

    Not phased

    Ages

    18 and older

    Site

    Urology Centers of Alabama, Homewood, Alabama

    Locations

    22 in total

    Run by

    Valencia Technologies Corporation

    See if you can join NCT05685433 on ClinicalTrials.gov

15. Predictive Utility and Mechanisms of Sacral Evoked Responses in Sacral Neuromodulation

    Electrical stimulation of the sacral nerve can help with bladder problems and pelvic pain but researchers don't understand exactly how the stimulation helps. The goal of this study is to examine signals evoked during sacral neuromodulation (SNM or electrical stimulation of the sacral nerve) and the…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Michigan, Ann Arbor, Michigan

    Run by

    University of Michigan

    See if you can join NCT06983470 on ClinicalTrials.gov

16. At-Home Transcutaneous Tibial Nerve Stimulation for Overactive Bladder in Rural Women

    This study contains a mixed-methods design consisting of a single-arm, interventional study and prospective patient interviews evaluating a novel self-implemented at-home Transcutaneous Tibial Nerve Stimulation (TTNS) treatment protocol for management of treatment naïve overactive bladder (OAB) amo…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Oregon Health & Science University, Portland, Oregon

    Run by

    Oregon Health and Science University

    See if you can join NCT07178314 on ClinicalTrials.gov

17. Bladder Botox UTI Antibiotic Prophylaxis

    Overactive bladder (OAB) is a common condition with a prevalence of 17% in the general population that significantly affects quality of life. Intradetrusor onabotulinumtoxinA injections are an advanced therapy for OAB as well as interstitial cystitis/bladder pain syndrome (IC/BPS). The most common …

    Stage

    Phase 4

    Ages

    18 and older

    Site

    Walter Reed National Military Medical Center, Bethesda, Maryland

    Run by

    Walter Reed National Military Medical Center

    See if you can join NCT06387329 on ClinicalTrials.gov

18. Antibiotic Usage Prior to OnabotulinumtoxinA Injection

    Intradetrusor injection of onabotulinumtoxinA, which is performed through a cystoscopic procedure, has been demonstrated to be efficacious in the treatment of both neurogenic and non-neurogenic overactive bladder (OAB), and is FDA approved as a treatment for overactive bladder. Intradetrusor of ona…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Stony Brook Medicine, Stony Brook, New York

    Run by

    Benaroya Research Institute

    See if you can join NCT04754737 on ClinicalTrials.gov

19. Standard Injections Versus Reduced Injections for Intravesical onabotulinumtoxinA Treatment of Overactive Bladder

    OnabotulinumtoxinA is an effective treatment for both idiopathic and neurogenic overactive bladder and was FDA approved for this indication in 2013. The standard technique for injecting onabotulinumtoxinA into the detrusor is mixing 100 units of onabotulinumtoxinA into 10mL of injectable normal sal…

    Stage

    Phase 4

    Ages

    18 and older

    Site

    Walter Reed National Military Medical Center, Bethesda, Maryland

    Run by

    Walter Reed National Military Medical Center

    See if you can join NCT04020510 on ClinicalTrials.gov