Non-Hodgkin Lymphoma Clinical Trials

64 studies are recruiting for non-hodgkin lymphoma in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies, page 3

  1. AS-1763 in Patients With Previously Treated CLL/SLL or Non-Hodgkin Lymphoma

    This is an open-label, multi-center Phase 1b clinical study of oral AS-1763 (docirbrutinib) in patients with CLL/SLL or B-cell NHL who have failed or are intolerant to ≥2 lines of systemic therapy.

    Stage
    Phase 1
    Ages
    18 and older
    Site
    UC Irvine Health, Orange, California
    Locations
    13 in total
    Run by
    Carna Biosciences, Inc.
  2. Mozobil for Autologous Hematopoietic Stem Cell Transplantation

    This prospective trial investigates the approach of G-CSF with risk-adapted Plerixafor use for stem cell mobilization in patients undergoing autologous stem cell transplantation. Since FDA approval in 2008, Plerixafor has been combined with G-CSF to mobilize stem cells, though this regimen has been…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Thomas Jefferson University Hospital, Philadelphia, Pennsylvania
    Run by
    Thomas Jefferson University
  3. A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

    This is an open-label, multicenter, Phase 1/2 study evaluating the safety and efficacy of CTX112™ in subjects with relapsed or refractory B-cell malignancies.

    Stage
    Phase 1
    Ages
    18 and older
    Site
    University of Kansas, Westwood, Kansas
    Locations
    7 in total
    Run by
    CRISPR Therapeutics AG
  4. Auto Stem Cell Transplant for Lymphoma Patients

    This is a phase II study of autologous transplant for patients with Hodgkin (HL) and non-Hodgkin lymphomas (NHL) including those who are HIV positive.

    Stage
    Phase 2
    Ages
    Up to 75
    Site
    Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota
    Run by
    Masonic Cancer Center, University of Minnesota
  5. Two Step Haplo With Radiation Conditioning

    This phase II clinical trial evaluates whether a modified modality of conditioning reduces treatment-related mortality (TRM) in patients who undergo a hematopoietic stem cell transplant (HSCT) for a hematological malignancy. HSCT is a curative therapy for many hematopoietic malignancies, however th…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadephia, Pennsylvania
    Run by
    Thomas Jefferson University
  6. SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

    International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and its clinical impact on pts with advanced cancer to facilitate clinical…

    Stage
    Not phased
    Ages
    Any age
    Site
    Massive Bio SYNERGY-AI site, Birmingham, Alabama
    Locations
    68 in total
    Run by
    Massive Bio, Inc.
  7. Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

    This phase I trial studies the safety of transplantation with a haploidentical donor peripheral blood stem cell graft depleted of TCRαβ+ cells and CD19+ cells in conjunction with the immunomodulating drug, Zoledronate, given in the post-transplant period to treat pediatric patients with relapsed or…

    Stage
    Phase 1
    Ages
    0 to 21
    Site
    University of Wisconsin Carbone Cancer Center, Madison, Wisconsin
    Run by
    University of Wisconsin, Madison
  8. Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

    This research is being done to investigate the safety and effectiveness of Darzalex Faspro (daratumumab and hyaluronidase-fihj) (a monoclonal antibody that targets plasma cells that make antibodies) and whether it can lower donor specific antibodies (DSA) levels to low enough levels to permit patie…

    Stage
    EARLY_Phase 1
    Ages
    18 and older
    Site
    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland
    Run by
    Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  9. Evaluate Safety of Axicabtagene Ciloleucel Reinfusion (Axi-Cel-2) in Patients With Relapsed and/or Refractory Second Line High-Risk Non-Hodgkin Lymphoma After Standard of Care Axi-Cel

    This is a phase Ib study to establish safety of Axi-Cel-2 in patients with Large B Cell Lymphoma (LBCL) who are at high risk of relapse.

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Stanford University, Palo Alto, California
    Run by
    Stanford University
  10. Obinutuzumab and ICE Chemotherapy in Refractory/Recurrent CD20+ Mature NHL

    The purpose of this study is to determine the safety of administering obinutuzumab as a single agent alone and in combination with ifosfamide, carboplatin, and etoposide (ICE) chemotherapy and determine the response rate of this treatment for children, adolescents and young adults (CAYA) with relap…

    Stage
    Phase 2
    Ages
    3 to 31
    Site
    New York Medical College, Valhalla, New York
    Run by
    New York Medical College
  11. AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion

    Children, adolescents, and young adults with malignant and non-malignant conditionsundergoing an allogeneic stem cell transplantation (AlloSCT) will have the stem cells selected utilizing α/β CD3+/CD19+ cell depletion. All other treatment is standard of care.

    Stage
    Phase 2
    Ages
    0 to 30
    Site
    New York Medical College, Valhalla, New York
    Run by
    Mitchell Cairo
  12. T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)

    This is an open-label, dose escalation, multi-center, Phase I/II clinical trial to assess the safety of an autologous T-cell therapy (EB103) and to determine the Recommended Phase II Dose (RP2D) in adult subjects (≥ 18 years of age) who have relapsed/refractory (R/R) B-cell NHL. The study will incl…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    University of California, Davis, Sacramento, California
    Locations
    2 in total
    Run by
    Estrella Biopharma, Inc.
  13. Chemoradiotherapy With Targeted Immunotherapy in Pediatric Lymphoma

    The addition of targeted immunotherapy will be safe and well tolerated and facilitate the reduction of anthracycline exposure while preserving lymphoma disease control in children, adolescents and young adults (CAYA) with mature B-cell non-Hodgkin lymphoma (MB-NHL) and classical Hodgkin lymphoma (c…

    Stage
    Phase 2
    Ages
    3 to 39
    Site
    University of Flordia, Gainsville, Florida
    Locations
    3 in total
    Run by
    New York Medical College
  14. Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLL

    This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, combined with acalabrutinib for the treatment of adults with Diffuse Large B-Cell Lymphoma and Chronic Lymphocytic Leukemia. Participants must be relapsed/refractory (having failed prior therapy)

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Goshen Center for Cancer Care, Goshen, Indiana
    Locations
    45 in total
    Run by
    Kartos Therapeutics, Inc.

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.