Neuropathic Pain Clinical Trials

18 studies are recruiting for neuropathic pain in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

1. Virtual Reality (VR) Self-Hypnosis Software

   This single-site study of self-hypnosis software using an off-the-shelf virtual reality (VR) device (OculusGo™) to determine the software's safety, usability, and preliminary efficacy in pain relief for HIV-associated chronic pain patients. This is funded under the i Prism Funding through Mount Sin…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Icahn School of Medicine at Mount Sinai, New York, New York

   Run by

   Icahn School of Medicine at Mount Sinai

   See if you can join NCT06398847 on ClinicalTrials.gov

2. Novel Soluble Epoxide Hydrolase Inhibitor for Neuropathic Pain in Patients With Spinal Cord Injury

   The goal of this clinical trial is to evaluate safety and tolerability of multiple oral doses of EC5026 in male and female patients with neuropathic pain due to traumatic or non-traumatic (degenerative) spinal cord injury. The main question it aims to answer is whether EC5026 is safe and well toler…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   AU Medical Center, Augusta, Georgia

   Run by

   EicOsis Human Health Inc.

   See if you can join NCT06438471 on ClinicalTrials.gov

3. The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture

   This application addresses the Peer Reviewed Medical Research Program Investigator-Initiated Research Award FY21 W81XWH-22-CPMRP-IIRA area of Chronic Pain Management Research Program- The investigators will utilize subjects who have sustained ankle fractures and may develop chronic pain following b…

   Stage

   Not phased

   Ages

   18 to 85

   Site

   Indiana University School of Medicine, Indianapolis, Indiana

   Run by

   Indiana University

   See if you can join NCT06420141 on ClinicalTrials.gov

4. Real-World Efficacy of Evoke® Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy in Chronic Pain Patients (ULTRA).

   This observational, prospective data collection is designed to evaluate the efficacy of CL-SCS therapy in real-world patients suffering from chronic pain.

   Stage

   Not phased

   Ages

   18 and older

   Site

   The Spine and Nerve Center of Saint Francis Hospital, Charleston, West Virginia

   Run by

   Saint Francis Hospital

   See if you can join NCT06246526 on ClinicalTrials.gov

5. Safety, Tolerability, and Pharmacokinetics of ASCT-83 in Healthy Adults

   The goal of this clinical trial is to learn if ASCT-83 is safe and well-tolerated and measure how ASCT-83 is absorbed, distributed, and eliminated from the body over time. The study will be conducted in healthy adults. The main questions this study will answer are: * Is ASCT-83 safe at clinical dos…

   Stage

   Phase 1

   Ages

   18 to 64

   Site

   Nucleus Network Minneapolis Clinic, Saint Paul, Minnesota

   Run by

   Alcamena Stem Cell Therapeutics

   See if you can join NCT07363395 on ClinicalTrials.gov

6. Brain Connectivity Changes With Spinal Cord Stimulation and Treatment of Chronic Pain: A Resting State NIRS/EEG Study

   This study aims to assess how use of spinal cord stimulation for the treatment of chronic pain impacts brain structure and function. The investigators will use a non-invasive neuroimaging technique called resting state Near Infrared Spectroscopy and Electroencephalography (rs-fNIRS/EEG). The invest…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Louis Stokes VA Medical Center, Cleveland, OH, Cleveland, Ohio

   Run by

   VA Office of Research and Development

   See if you can join NCT05811312 on ClinicalTrials.gov

7. Pain Outcomes After Digital Amputation Using Tulavi Allay™ Nerve Cap

   In 2016, one in five individuals in the United States (US) experienced chronic pain, and approximately 40% of them suffered from neuropathic pain. The physical and emotional burden on patients results in costs of billions of dollars annually. Digital amputations affect over 23,000 people each year …

   Stage

   Phase 2

   Ages

   22 and older

   Site

   Massachusetts General Hospital, Boston, Massachusetts

   Run by

   Massachusetts General Hospital

   See if you can join NCT06915662 on ClinicalTrials.gov

8. Proof of Concept Trial of Cannabis Derivatives in Neuropathic Pain

   Chronic neuropathic pain (CNP) is disabling. Research on frontline treatments for CNP, shows inconsistent outcomes and dissatisfaction among Veterans. Veterans and clinicians have shown significant interest in cannabis derivatives (THC, CBD) for neuropathic pain control, but there are no well-contr…

   Stage

   Phase 2

   Ages

   21 and older

   Site

   VA San Diego Healthcare System, San Diego, CA, San Diego, California

   Locations

   6 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT05351801 on ClinicalTrials.gov

9. Diabetic Neuropathy in Spinal Cord Stimulator Patients

   The objective of this study is to assess the effect Spinal Cord Stimulators have toward improving vascular changes of diabetes mellitus in patients eligible for SCS placement based on their condition of painful diabetic neuropathy; we will evaluate improving their disability and quality of life, im…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Chicago Medical Center, Chicago, Illinois

   Run by

   University of Chicago

   See if you can join NCT04687215 on ClinicalTrials.gov

10. Ginger Root Extract for Sciatic Pain Individuals

    Neuropathic pain affects the quality of life of many Americans. Non-pharmacological strategies such as bioactive compounds in foods are being explored as therapeutics but can also serve as tools to better understand pain mechanisms. The previous study reported that ginger root extract supplementati…

    Stage

    Phase 2

    Ages

    18 to 85

    Site

    Texas Tech University Health Sciences Center, Lubbock, Texas

    Locations

    2 in total

    Run by

    Leslie Shen

    See if you can join NCT06817018 on ClinicalTrials.gov

11. Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury

    The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with chronic spinal cord injury.

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Alabama at Birmingham, Birmingham, Alabama

    Locations

    3 in total

    Run by

    Texas A&M University

    See if you can join NCT05005026 on ClinicalTrials.gov

12. Virtual Walking Therapy for Neuropathic Pain Following Incomplete Spinal Cord Injury

    The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with incomplete spinal cord injury.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Texas A&M University, College Station, Texas

    Run by

    Texas A&M University

    See if you can join NCT06330181 on ClinicalTrials.gov

13. Utility of Multisensory Body-Representation in Spinal Cord Injury (SCI) With Pain

    The purpose of this study is to investigate the effectiveness of bodily illusions combined with transcranial direct current stimulation (tDCS) on neuropathic pain symptoms and sensory functions in participants with spinal cord injury (SCI) and neuropathic pain.

    Stage

    Not phased

    Ages

    18 to 70

    Site

    University of Miami, Miami, Florida

    Run by

    University of Miami

    See if you can join NCT06010251 on ClinicalTrials.gov

14. Neuropathic Pain and Operant Conditioning of Cutaneous Reflexes After SCI

    The purpose of the second part of the study is to examine the effect of reflex training in the leg to decrease neuropathic pain. For this, the researchers are recruiting 15 individuals with neuropathic pain due to spinal cord injury to participate in the reflex training procedure. The study involve…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Medical University of South Carolina, Charleston, South Carolina

    Run by

    Medical University of South Carolina

    See if you can join NCT05492188 on ClinicalTrials.gov

15. Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA

    This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary goal of the study is to use fluctuations in daily self-reported symptoms…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Brown University, Providence, Rhode Island

    Run by

    Brown University

    See if you can join NCT05754190 on ClinicalTrials.gov

16. The Effect of Outpatient Ketamine Infusion on Chronic Neuropathic Pain and PTSD

    This study is aimed to evaluate outpatient ketamine infusion within a military chronic neuropathic pain population and its effect on PTSD. Currently, this is a pilot study with 30 participants. Participants will be randomized to (1) a moderate dose ketamine, (2) moderate dose ketamine +Mg, or (3) a…

    Stage

    Phase 4

    Ages

    18 to 70

    Site

    Brooke Army Medical Center, San Antonio, Texas

    Run by

    Margaux M. Salas, PhD

    See if you can join NCT06414356 on ClinicalTrials.gov

17. Insula Neuromodulation for Chronic Neuropathic Pain

    This study will comprehensively investigate the insula as a brain target for neuromodulation to treat chronic neuropathic pain.

    Stage

    Not phased

    Ages

    18 to 80

    Site

    University of Virginia, Charlottesville, Virginia

    Run by

    University of Virginia

    See if you can join NCT05404581 on ClinicalTrials.gov

18. Novel Stimulation Patterns to Improve the Effectiveness of Spinal Cord Stimulation

    The goal of this study is to compare pain outcomes achieved by spinal cord stimulation (SCS) using time varying stimulation patterns with pain outcomes achieved by current standard of care SCS.

    Stage

    Not phased

    Ages

    22 and older

    Site

    Baylor College of Medicine, Houston, Texas

    Run by

    Ashwin Viswanathan

    See if you can join NCT05968664 on ClinicalTrials.gov