Neurodevelopmental Disorders Clinical Trials

15 studies are recruiting for neurodevelopmental disorders in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age

   Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and neurodevelopmental impairments (NDI) at significant rates, disproportionate to their term peers. Ea…

   Stage

   Not phased

   Ages

   0 to 6

   Site

   Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois

   Run by

   Ann & Robert H Lurie Children's Hospital of Chicago

   See if you can join NCT05336890 on ClinicalTrials.gov

2. The Effects of the Melillo Method® on Biopsychosocial Outcomes in School-Age Children

   This pilot study will test whether a school-based neurodevelopmental brain-training program, called the Melillo Method®, is feasible to deliver and study in elementary and middle school students who are struggling with behavior and learning. The study will enroll about 34 children ages 8 and older …

   Stage

   Not phased

   Ages

   8 and older

   Site

   North Greene School District, Roodhouse, Illinois

   Run by

   Life University

   See if you can join NCT07779889 on ClinicalTrials.gov

3. Natural History Study of GEMIN-5 Related Neurodevelopmental Disorder

   This study will include a comprehensive retrospective chart review and a longitudinal prospective observational natural history study to characterize the phenotypic spectrum of GEMIN5-Related Neurodevelopmental Disorder. We aim to define the trajectory of this ultra-rare disease, core clinical feat…

   Stage

   Not phased

   Ages

   Any age

   Site

   Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

   Run by

   University of Pittsburgh

   See if you can join NCT06776341 on ClinicalTrials.gov

4. Rett Syndrome Registry

   The Rett Syndrome Registry is a longitudinal observational study of individuals with MECP2 mutations and a diagnosis of Rett syndrome. Designed together with the IRSF Rett Syndrome Center of Excellence Network medical directors, this study collects data on the signs and symptoms of Rett syndrome as…

   Stage

   Not phased

   Ages

   0 to 99

   Site

   University of Alabama, Birmingham, Alabama

   Locations

   19 in total

   Run by

   International Rett Syndrome Foundation

   See if you can join NCT05432349 on ClinicalTrials.gov

5. Patterns of Neurodevelopmental Disorders

   The purpose of this study is to systematically evaluate the results of medical investigations to identify symptom and biological patterns and common etiologies of neurodevelopmental disorders.

   Stage

   Not phased

   Ages

   Any age

   Site

   Rossignol Medical Center, Phoenix, Arizona

   Run by

   Richard Frye

   See if you can join NCT06213090 on ClinicalTrials.gov

6. Motor-voice Assessment in Infants (MAMI)

   The goal of this observational study is to discover features of normal and disordered motor-voice profiles that are biobehavioral markers of physical disability in infants.. The main questions it aims to answer are: Identify voice factors among infants with newborn-detectable risk. Identify associa…

   Stage

   Not phased

   Ages

   Up to 0

   Site

   The Ohio State University, Columbus, Ohio

   Run by

   Ohio State University

   See if you can join NCT06807203 on ClinicalTrials.gov

7. Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders

   This observational study evaluates functional and developmental outcomes in pediatric participants undergoing a two week intensive multimodal neurorehabilitation program. The program is designed for children with neurodevelopmental disorders, including but not limited to cerebral palsy, autism spec…

   Stage

   Not phased

   Ages

   4 to 12

   Site

   Ability and Beyond, The Woodlands, Texas

   Run by

   Healing Hope International

   See if you can join NCT07493096 on ClinicalTrials.gov

8. Reducing Missed Appointments

   There are four goals of this project: (1) To examine the impact of different appointment reminder messages on appointment attendance; (2) to determine the added benefit of a patient navigator reaching out in advance of appointments to families at elevated risk of missing their appointment, and dete…

   Stage

   Phase 3

   Ages

   0 to 24

   Site

   Kennedy Krieger Institute, Baltimore, Maryland

   Run by

   Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

   See if you can join NCT06915480 on ClinicalTrials.gov

9. Physical Activity and Community EmPOWERment Project

   Purpose: Conduct a wait-list randomized controlled trial (RCT) of an inclusive physical activity program called PACE for adults with intellectual disability (ID) who are not yet showing signs of Alzheimer's Disease (AD)/age-related dementias (ARD). Participants: Participants include 120 adults with…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of North Carolina, Chapel Hill, North Carolina

   Locations

   2 in total

   Run by

   University of North Carolina, Chapel Hill

   See if you can join NCT06740162 on ClinicalTrials.gov

10. Longitudinal Study of Neurogenetic Disorders

    The purpose of this study is to analyze patterns in individuals with hnRNP (and other) genetic variants, including their neurological comorbidities, other medical problems and any treatment. The investigators will maintain an ongoing database of medical data that is otherwise being collected for ro…

    Stage

    Not phased

    Ages

    Any age

    Site

    Columbia University Irving Medical Center, New York, New York

    Run by

    Columbia University

    See if you can join NCT03492060 on ClinicalTrials.gov

11. Word Learning From Parentese in Autistic Children

    The overall objective of this research is to determine whether parentese delivered in the video format (Aim 1) and in live interaction (Aim 2) facilitates novel word learning in autistic children and to investigate if there are factors that influence the effect of parentese on word learning (Aim 3).

    Stage

    Not phased

    Ages

    1 to 4

    Site

    University of Texas at Dallas, Richardson, Texas

    Run by

    The University of Texas at Dallas

    See if you can join NCT06649916 on ClinicalTrials.gov

12. School-based Paraeducator Education for Engagement at Recess

    The purpose of the proposed three-site study is to test whether an educator-level implementation strategy, coaching, with or without a school-level implementation strategy, school-based teams, will maximize paraeducators' use (fidelity and sustainment) of an evidence-based social engagement interve…

    Stage

    Not phased

    Ages

    5 and older

    Site

    University of Washington, Seattle, Washington

    Locations

    3 in total

    Run by

    University of Washington

    See if you can join NCT06559267 on ClinicalTrials.gov

13. HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis

    Babies with single ventricle congenital heart disease (SVCHD) are often diagnosed during pregnancy. While prenatal diagnosis has important clinical benefits, it is often stressful and overwhelming for parents, and many express a need for psychological support. HeartGPS is a psychological interventi…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Children's Hospital Medical Center, Cincinnati, Cincinnati, Ohio

    Locations

    4 in total

    Run by

    Children's Hospital Medical Center, Cincinnati

    See if you can join NCT06175104 on ClinicalTrials.gov

14. Genetic Inclusion by Virtual Evaluation

    This study aims to transform the current clinical practice paradigm by leveraging an internally designed web-based model of delivery of care called Consultagene to provide remote evaluation and genomic sequencing for improving genetic health of less resourced children with rare disorders living alo…

    Stage

    Not phased

    Ages

    0 to 18

    Site

    University of Texas Rio Grande Valley, Edinburg, Texas

    Run by

    Baylor College of Medicine

    See if you can join NCT05318222 on ClinicalTrials.gov

15. SQUED™ Series 28.1 Home-use and Treatment of Autowave Reverberator of Autism

    Locomotor, transport and information functions in human body systems are carried out by active media in autowave regimes! Any living organism is a (micro-macro-mega) hierarchy of autowave subsystems-an ensemble of loosely coupled subsystems of a simpler structure. From the highest levels of the hie…

    Stage

    Not phased

    Ages

    0 to 21

    Site

    World Autism Center, American Federation of Medical Synergetics, Department of Neurology; Cognitive Neurology/Neuropsychology WOMS, Louisville, Kentucky

    Locations

    2 in total

    Run by

    American Federation of Medical Synergetics

    See if you can join NCT03222375 on ClinicalTrials.gov