Neuroblastoma Clinical Trials in Minneapolis, Minnesota

7 studies are recruiting for neuroblastoma in Minneapolis, Minnesota right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

   This phase III trial tests how well the addition of dinutuximab to Induction chemotherapy along with standard of care surgical resection of the primary tumor, radiation, stem cell transplantation, and immunotherapy works for treating children with newly diagnosed high-risk neuroblastoma. Dinutuxima…

   Stage

   Phase 3

   Ages

   Up to 30

   Site

   Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

   Locations

   179 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT06172296 on ClinicalTrials.gov

2. Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

   A prospective open label, multicenter study to evaluate the feasibility and acute toxicity of using molecularly guided therapy in combination with standard therapy followed by a Randomized Controlled Trial of standard immunotherapy with or without DFMO followed by DFMO maintenance for Newly Diagnos…

   Stage

   Phase 2

   Ages

   Up to 22

   Site

   Children's Hospital and Clinics of Minnesota, Minneapolis, Minnesota

   Locations

   28 in total

   Run by

   Giselle Sholler

   See if you can join NCT02559778 on ClinicalTrials.gov

3. Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

   This phase III trial studies iobenguane I-131 or lorlatinib and standard therapy in treating younger patients with newly-diagnosed high-risk neuroblastoma or ganglioneuroblastoma. Radioactive drugs, such as iobenguane I-131, may carry radiation directly to tumor cells and not harm normal cells. Lor…

   Stage

   Phase 3

   Ages

   1 to 30

   Site

   Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

   Locations

   164 in total

   Run by

   Children's Oncology Group

   See if you can join NCT03126916 on ClinicalTrials.gov

4. Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

   This phase I/II trial evaluates the highest safe dose, side effects, and possible benefits of tegavivint in treating patients with solid tumors that has come back (recurrent) or does not respond to treatment (refractory). Tegavivint interferes with the binding of beta-catenin to TBL1, which may hel…

   Stage

   Phase 1

   Ages

   1 to 30

   Site

   University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

   Locations

   21 in total

   Run by

   Children's Oncology Group

   See if you can join NCT04851119 on ClinicalTrials.gov

5. Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

   This is a prospective, multicenter clinical trial in subjects with newly diagnosed high-risk neuroblastoma to evaluate the efficacy and safety of administering naxitamab with standard induction therapy. The initial chemotherapy will include 5 cycles of multi-agent chemotherapy. Naxitamab will be ad…

   Stage

   Phase 2

   Ages

   1 to 21

   Site

   Children's Hospital and Clinics of Minnesota, Minneapolis, Minnesota

   Locations

   26 in total

   Run by

   Giselle Sholler

   See if you can join NCT05489887 on ClinicalTrials.gov

6. Myeloablative Consolidation Therapy and Tandem Autologous Stem Cell Rescue in Patients With High-Risk Neuroblastoma

   This is a phase II single center study to administer two courses of myeloablative consolidation chemotherapy each followed by an autologous peripheral blood stem cell (PBSC) rescue in patients with high-risk neuroblastoma who have completed induction chemotherapy (independent of this study). Ideall…

   Stage

   Phase 2

   Ages

   Up to 30

   Site

   Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota

   Run by

   Masonic Cancer Center, University of Minnesota

   See if you can join NCT02605421 on ClinicalTrials.gov

7. International PPB/DICER1 Registry

   Pleuropulmonary blastoma (PPB) is a rare malignant neoplasm of the lung presenting in early childhood. Type I PPB is a purely cystic lesion, Type II is a partially cystic, partially solid tumor, Type III is a completely solid tumor. Treatment of children with PPB is at the discretion of the treatin…

   Stage

   Not phased

   Ages

   Up to 100

   Site

   Children's Minnesota, Minneapolis, Minnesota

   Run by

   Children's Hospitals and Clinics of Minnesota

   See if you can join NCT03382158 on ClinicalTrials.gov