Neuroblastoma Clinical Trials in Gainesville, Florida

7 studies are recruiting for neuroblastoma in Gainesville, Florida right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

   This phase III trial tests how well the addition of dinutuximab to Induction chemotherapy along with standard of care surgical resection of the primary tumor, radiation, stem cell transplantation, and immunotherapy works for treating children with newly diagnosed high-risk neuroblastoma. Dinutuxima…

   Stage

   Phase 3

   Ages

   Up to 30

   Site

   UF Health Cancer Institute - Gainesville, Gainesville, Florida

   Locations

   179 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT06172296 on ClinicalTrials.gov

2. Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas

   The purpose of this study is to evaluate the investigational oral drug AMXT 1501 in combination with oral eflornithine (DFMO). An investigational drug is one that has not been approved by the U.S. Food \& Drug Administration (FDA), or any other regulatory authorities around the world for use alone …

   Stage

   Phase 1

   Ages

   Up to 26

   Site

   University of Florida, Gainesville, Florida

   Locations

   14 in total

   Run by

   Milton S. Hershey Medical Center

   See if you can join NCT06465199 on ClinicalTrials.gov

3. Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors

   The purpose of this study is to evaluate the investigational drug, silmitasertib (a pill taken by mouth), in combination with FDA approved drugs for solid tumors. An investigational drug is one that has not been approved by the U.S. Food \& Drug Administration (FDA), or any other regulatory authori…

   Stage

   Phase 1

   Ages

   Up to 30

   Site

   University of Florida, Gainesville, Florida

   Locations

   23 in total

   Run by

   Milton S. Hershey Medical Center

   See if you can join NCT06541262 on ClinicalTrials.gov

4. Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

   This phase III trial studies iobenguane I-131 or lorlatinib and standard therapy in treating younger patients with newly-diagnosed high-risk neuroblastoma or ganglioneuroblastoma. Radioactive drugs, such as iobenguane I-131, may carry radiation directly to tumor cells and not harm normal cells. Lor…

   Stage

   Phase 3

   Ages

   1 to 30

   Site

   UF Health Cancer Institute - Gainesville, Gainesville, Florida

   Locations

   164 in total

   Run by

   Children's Oncology Group

   See if you can join NCT03126916 on ClinicalTrials.gov

5. Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

   This is a prospective, multicenter clinical trial in subjects with newly diagnosed high-risk neuroblastoma to evaluate the efficacy and safety of administering naxitamab with standard induction therapy. The initial chemotherapy will include 5 cycles of multi-agent chemotherapy. Naxitamab will be ad…

   Stage

   Phase 2

   Ages

   1 to 21

   Site

   University of Florida, Gainesville, Florida

   Locations

   26 in total

   Run by

   Giselle Sholler

   See if you can join NCT05489887 on ClinicalTrials.gov

6. PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy

   A Phase I open-label, multicenter study, to evaluate the safety, feasibility, and maximum tolerated dose (MTD) of treating children with newly diagnosed DIPG or recurrent neuroblastoma with molecular targeted therapy in combination with adoptive cell therapy (Total tumor mRNA-pulsed autologous Dend…

   Stage

   Phase 1

   Ages

   1 to 30

   Site

   University of Florida, Gainesville, Florida

   Locations

   3 in total

   Run by

   University of Florida

   See if you can join NCT04837547 on ClinicalTrials.gov

7. Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

   Hematopoietic stem cell transplantation can cure patients with blood cancer and other underlying diseases. αβ-T cell and B cell depletion has been introduced to decrease GVHD and PTLD and has demonstrated effectiveness for hematologic malignancies and non-malignant diseases additionally increasing …

   Stage

   Phase 1

   Ages

   0 to 25

   Site

   University of Florida, Gainesville, Florida

   Run by

   University of Florida

   See if you can join NCT06625190 on ClinicalTrials.gov