Neuroblastoma Clinical Trials in Charlotte, North Carolina

6 studies are recruiting for neuroblastoma in Charlotte, North Carolina right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

   This phase III trial tests how well the addition of dinutuximab to Induction chemotherapy along with standard of care surgical resection of the primary tumor, radiation, stem cell transplantation, and immunotherapy works for treating children with newly diagnosed high-risk neuroblastoma. Dinutuxima…

   Stage

   Phase 3

   Ages

   Up to 30

   Site

   Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

   Locations

   179 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT06172296 on ClinicalTrials.gov

2. Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

   Background: - Laboratory investigators who are studying common childhood cancers are interested in developing a tissue repository to collect and store blood, serum, tissue, urine, or tumors of children who have cancer or adults who have common childhood cancers. To develop this repository, addition…

   Stage

   Not phased

   Ages

   0 and older

   Site

   Carolinas Medical Center/Levine Children's Hospital, Charlotte, North Carolina

   Locations

   5 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT01109394 on ClinicalTrials.gov

3. Pediatric Precision Laboratory Advanced Neuroblastoma Therapy

   A prospective open label, multicenter study to evaluate the feasibility and acute toxicity of using molecularly guided therapy in combination with standard therapy followed by a Randomized Controlled Trial of standard immunotherapy with or without DFMO followed by DFMO maintenance for Newly Diagnos…

   Stage

   Phase 2

   Ages

   Up to 22

   Site

   Levine Children's Hospital, Charlotte, North Carolina

   Locations

   28 in total

   Run by

   Giselle Sholler

   See if you can join NCT02559778 on ClinicalTrials.gov

4. Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

   This phase III trial studies iobenguane I-131 or lorlatinib and standard therapy in treating younger patients with newly-diagnosed high-risk neuroblastoma or ganglioneuroblastoma. Radioactive drugs, such as iobenguane I-131, may carry radiation directly to tumor cells and not harm normal cells. Lor…

   Stage

   Phase 3

   Ages

   1 to 30

   Site

   Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

   Locations

   164 in total

   Run by

   Children's Oncology Group

   See if you can join NCT03126916 on ClinicalTrials.gov

5. Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

   This is a prospective, multicenter clinical trial in subjects with newly diagnosed high-risk neuroblastoma to evaluate the efficacy and safety of administering naxitamab with standard induction therapy. The initial chemotherapy will include 5 cycles of multi-agent chemotherapy. Naxitamab will be ad…

   Stage

   Phase 2

   Ages

   1 to 21

   Site

   Levine Children's Hospital, Charlotte, North Carolina

   Locations

   26 in total

   Run by

   Giselle Sholler

   See if you can join NCT05489887 on ClinicalTrials.gov

6. PEACH TRIAL- Precision Medicine and Adoptive Cellular Therapy

   A Phase I open-label, multicenter study, to evaluate the safety, feasibility, and maximum tolerated dose (MTD) of treating children with newly diagnosed DIPG or recurrent neuroblastoma with molecular targeted therapy in combination with adoptive cell therapy (Total tumor mRNA-pulsed autologous Dend…

   Stage

   Phase 1

   Ages

   1 to 30

   Site

   Levine Children's Hospital, Charlotte, North Carolina

   Locations

   3 in total

   Run by

   University of Florida

   See if you can join NCT04837547 on ClinicalTrials.gov