Myelofibrosis Clinical Trials in Los Angeles, California

4 studies are recruiting for myelofibrosis in Los Angeles, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Study of DISC-0974 (RALLY-MF) in Participants With Myelofibrosis or Myelodysplastic Syndrome and Anemia

    This phase 1b/2a open-label study will evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and clinical activity of DISC-0974 as well as categorize the effects on hematologic response in participants with myelofibrosis or myelodysplastic syndrome and anemia.

    Stage
    Phase 1
    Ages
    18 and older
    Site
    UCLA, Los Angeles, California
    Locations
    32 in total
    Run by
    Disc Medicine, Inc

    See if you can join NCT05320198 on ClinicalTrials.gov

  2. A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

    This study is a Phase 1/2, multicenter, dose-escalation, open-label trial to assess safety, tolerability, pharmacokinetics and pharmacodynamics of nuvisertib (TP-3654) in patients with intermediate or high-risk primary or secondary MF.

    Stage
    Phase 1
    Ages
    18 and older
    Site
    University of Southern California, Los Angeles, California
    Locations
    90 in total
    Run by
    Sumitomo Pharma America, Inc.

    See if you can join NCT04176198 on ClinicalTrials.gov

  3. Curcumin to Improve Inflammation and Symptoms in Patients With Clonal Cytopenia of Undetermined Significance, Low Risk Myelodysplastic Syndrome, and Myeloproliferative Neoplasms

    This phase II trial evaluates how a curcumin supplement (C3 complex/Bioperine) changes the inflammatory response and symptomatology in patients with clonal cytopenia of undetermined significance (CCUS), low risk myelodysplastic syndrome (LR-MDS), and myeloproliferative neoplasms (MPN). Chronic infl…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Los Angeles General Medical Center, Los Angeles, California
    Locations
    2 in total
    Run by
    University of Southern California

    See if you can join NCT06063486 on ClinicalTrials.gov

  4. Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

    This clinical trial is evaluating whether addition of navtemadlin to ruxolitinib treatment will provide more clinical benefit than ruxolitinib alone for patients with Myelofibrosis who have a suboptimal response to ruxolitinib treatment alone. Subjects will start by receiving ruxolitinib alone in t…

    Stage
    Phase 3
    Ages
    18 and older
    Site
    UCLA Hematology/Oncology Clinic - Los Angeles, Los Angeles, California
    Locations
    215 in total
    Run by
    Kartos Therapeutics, Inc.

    See if you can join NCT06479135 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.