Myelodysplastic Syndromes Clinical Trials in The Bronx, New York

5 studies are recruiting for myelodysplastic syndromes in The Bronx, New York right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

   Study ASTX030-01 is a multi-phase study comprising of Phases 1-3 Monotherapy arms, and Phase 1 and Phase 2 Combination Therapy arms. Phase 1 Monotherapy consists of an open-label Dose Escalation Stage (Stage A) using multiple cohorts at escalating dose levels of oral cedazuridine and azacitidine (o…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Montefiore Medical Center, The Bronx, New York

   Locations

   71 in total

   Run by

   Taiho Oncology, Inc.

   See if you can join NCT04256317 on ClinicalTrials.gov

2. Venetoclax Plus Intensive Chemotherapy in AML and Advanced MDS

   This is a Phase 1b, open-label study evaluating Venetoclax in combination with intensive induction and consolidation chemotherapy in previously untreated, adult patients with acute myeloid leukemia. In Part 1, the dose escalation phase, the safety and tolerability of the combination with Venetoclax…

   Stage

   Phase 1

   Ages

   18 to 75

   Site

   Montefiore Einstein Cancer Center and Children's Hospital at Montefiore (CHAM), The Bronx, New York

   Run by

   Montefiore Medical Center

   See if you can join NCT05342584 on ClinicalTrials.gov

3. Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML

   Myeloid malignancies which include AML (acute myeloid leukemia) and MDS (myelodysplatic syndrome) are cancers of the bone marrow which lead to bone marrow failure. The bone marrow is the place or factory in the body where components of blood such as red cells, platelets and white cells are made. In…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Montefiore Medical Center, The Bronx, New York

   Locations

   3 in total

   Run by

   Montefiore Medical Center

   See if you can join NCT05184842 on ClinicalTrials.gov

4. Study of SX-682 Alone and in Combination With Oral or Intravenous Decitabine in Subjects With Myelodysplastic Syndrome

   This study will determine the safety profile, maximum tolerated dose (MTD), dose-limiting toxicities (DLT), and recommended Phase 2 dose (RP2D) of SX-682 in the treatment of patients with Myelodysplastic Syndromes (MDS).

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Montefiore Medical Center, The Bronx, New York

   Locations

   7 in total

   Run by

   Syntrix Biosystems, Inc.

   See if you can join NCT04245397 on ClinicalTrials.gov

5. Danvatirsen Monotherapy Followed by Combination With Venetoclax in Relapsed/Refractory MDS & AML

   This is a Phase 1 study investigating the safety and efficacy of Danvatirsen as a monotherapy followed by combination with Venetoclax in patients with relapsed/refractory myelodysplastic syndromes (MDS) or acute myeloid leukemia (AML). Funding Source: FDA OOPD

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Montefiore Medical Center, The Bronx, New York

   Locations

   2 in total

   Run by

   Montefiore Medical Center

   See if you can join NCT05986240 on ClinicalTrials.gov