Musculoskeletal Pain Clinical Trials

15 studies are recruiting for musculoskeletal pain in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Pragmatic Trial of EAET for Veterans With Chronic Pain

   About one in three Veterans lives with long-term (chronic) pain, and many of them also struggle with past trauma and mental health issues like depression, anxiety, or PTSD. Emotional Awareness and Expression Therapy (EAET) is a type of talk therapy that helps people understand and express their emo…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of California, Los Angeles, Los Angeles, California

   Run by

   University of California, Los Angeles

   See if you can join NCT07218757 on ClinicalTrials.gov

2. Video Intervention for Older Adults With Chronic Pain

   Chronic musculoskeletal (MSK) pain, which includes spinal pain, osteoarthritis, and fibromyalgia, is a common and costly problem for older adults and is associated with decreased quality of life. In this project, investigators propose to create Reclaim Your Day (RYD), which will consist of 6, 30-mi…

   Stage

   Not phased

   Ages

   55 and older

   Site

   Butler Hospital, Providence, Rhode Island

   Run by

   Butler Hospital

   See if you can join NCT07404618 on ClinicalTrials.gov

3. Virtual Reality (VR) Self-Hypnosis Software

   This single-site study of self-hypnosis software using an off-the-shelf virtual reality (VR) device (OculusGo™) to determine the software's safety, usability, and preliminary efficacy in pain relief for HIV-associated chronic pain patients. This is funded under the i Prism Funding through Mount Sin…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Icahn School of Medicine at Mount Sinai, New York, New York

   Run by

   Icahn School of Medicine at Mount Sinai

   See if you can join NCT06398847 on ClinicalTrials.gov

4. Weighted Blanket Use for Adults With Chronic Pain

   Chronic pain is a common condition that can affect sleep, daily functioning, and overall quality of life. Many individuals living with chronic pain seek non-medication approaches to help manage their symptoms. Weighted blankets are commonly used to promote relaxation and comfort during sleep, but t…

   Stage

   Not phased

   Ages

   18 and older

   Site

   National University of Natural Medicine, Portland, Oregon

   Run by

   National University of Natural Medicine

   See if you can join NCT07498491 on ClinicalTrials.gov

5. Equipping Patients Using Interventions for Pain and Depression

   This project is part of the NIH Helping to End Addiction Long-term (HEAL) initiative (https://heal.nih.gov/). This randomized controlled trial (RCT) is phase 2 of a two-phase, 5-year project with the overarching goal of testing a decision aid (DA)/coaching intervention, tailored to Black patients w…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Eskenazi Health Primary Care, Indianapolis, Indiana

   Run by

   Indiana University

   See if you can join NCT06500780 on ClinicalTrials.gov

6. Supraspinal Processing of Sensory Aspects of Pain

   The goal of this basic science study is to learn about the brain mechanisms of chronic pain across different chronic pain syndromes in pediatric patients. The main questions it aims to answer are: * Are there shared and distinct brain systems engaged by different forms of pediatric chronic pain? * …

   Stage

   Not phased

   Ages

   10 to 17

   Site

   Cincinnati Children's Hospital, Cincinnati, Ohio

   Run by

   Children's Hospital Medical Center, Cincinnati

   See if you can join NCT05814497 on ClinicalTrials.gov

7. The PROACTIVE Study for Black Elders

   Chronic musculoskeletal pain (CMP), while a leading cause of physical disablement, is a neglected national health disparity issue in Black communities. The purpose of this study is to test a novel culturally congruent pain self-management intervention. A total of 120 persons aged 50-92, self-identi…

   Stage

   Not phased

   Ages

   50 to 92

   Site

   University of Florida, Gainesville, Florida

   Run by

   University of Florida

   See if you can join NCT06512727 on ClinicalTrials.gov

8. The PROmoting Pain Self-Management (PROs) Trial: Holistic Pain Care in the Military Health System

   The goal of this study is to improve pain care in the MHS by identifying effective, whole-person, non-pharmacologic interventions for persons with chronic musculoskeletal pain. The investigators will evaluate two promising, evidence-based holistic health interventions and compare them to usual care.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Desmond Doss Health Clinic, Schofield Barracks, Hawaii

   Locations

   5 in total

   Run by

   Brooke Army Medical Center

   See if you can join NCT06940986 on ClinicalTrials.gov

9. The BRIDGE Pain Study

   The purpose of the study is to discover at least two distinct Musculoskeletal pain subtypes. These types are caused by different brain-and-immune system signals that affect how the body feels pain, and they are also shaped by a person's biology, psychology, and social environment. Aim 1. We want to…

   Stage

   Not phased

   Ages

   14 to 26

   Site

   Cincinnati Children's Hospital, Cincinnati, Ohio

   Run by

   Children's Hospital Medical Center, Cincinnati

   See if you can join NCT07602595 on ClinicalTrials.gov

10. Neural Mechanisms of Light Driven Analgesia

    The goal of this study will be to understand the biological mechanisms that are responsible to light-driven analgesia. Light presented to the retina has been shown to have pain relieving properties in pre-clinical and clinical studies. In this study the investigators will evaluate the functional co…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

    Run by

    University of North Carolina, Chapel Hill

    See if you can join NCT07245303 on ClinicalTrials.gov

11. Online Yoga vs Acceptance and Commitment Therapy for Treating Chronic Musculoskeletal Pain

    This study will compare online yoga with Acceptance and Commitment Therapy (ACT), an established treatment for chronic pain. We will compare the efficacy of the two treatments for reducing chronic musculoskeletal pain in veterans.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Palo Alto VA Medical Center, Palo Alto, California

    Run by

    Palo Alto Veterans Institute for Research

    See if you can join NCT06704061 on ClinicalTrials.gov

12. Group Medical Visits and Chiropractic Care for Older Adults With Chronic Spine Pain

    Chronic spine pain is one of the most common and conditions in adults over the age of 65. Treatments for pain that are non-pharmacologic (do not use over-the-counter or prescription drugs) are recognized as some of the most important to study. Chiropractic care has shown to be effective at reducing…

    Stage

    Not phased

    Ages

    65 and older

    Site

    MassGeneralBrigham, Boston, Massachusetts

    Run by

    Brigham and Women's Hospital

    See if you can join NCT06632535 on ClinicalTrials.gov

13. Improving Health for Older Adults With Pain Through Engagement

    The goal of this project is to conduct a randomized, hybrid type 1 effectiveness-implementation trial (N=200) to evaluate the effectiveness and implementation of a 10-week mind-body and walking program (GetActive+) vs treatment as usual (TAU). The investigators will test for improvements in self-re…

    Stage

    Not phased

    Ages

    55 and older

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT06119698 on ClinicalTrials.gov

14. Eastern Principles Acceptance and Commitment Therapy For Injury Prevention Among Nurses and Nursing Aides

    This clinical trial will evaluate the effectivness of an Eastern Principles Acceptance and Commitment Therapy intervention (EPACT) relative to an estabished traditional Western-based Acceptance and Commitment Therapy intervention (ACT) and a no treatment control group. The participants for the stud…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Bowling Green State University, Bowling Green, Ohio

    Run by

    Bowling Green State University

    See if you can join NCT06813495 on ClinicalTrials.gov

15. Overlapping Pain Trajectory Study

    The goal of this observational study is to learn about spatial and temporal nociceptive filtering in adolescents with chronic overlapping pain conditions (COPCs). The main questions it aims to answer are: 1. If spatial and temporal filtering of nociceptive information is disrupted in youth with COP…

    Stage

    Not phased

    Ages

    10 to 19

    Site

    Cincinnati Children's Hospital, Cincinnati, Ohio

    Run by

    Children's Hospital Medical Center, Cincinnati

    See if you can join NCT05752396 on ClinicalTrials.gov