Metastatic Prostate Cancer Clinical Trials in Boston, Massachusetts

6 studies are recruiting for metastatic prostate cancer in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial

   The purpose of this study is to determine whether a 16-week supervised, clinic-based circuit training intervention utilizing resistance and functional exercises and self-directed aerobic exercise will improve frailty and sarcopenic status and disease progression outcomes among pre-frail/frail metas…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Brigham and Women's Hospital, Boston, Massachusetts

   Locations

   3 in total

   Run by

   Dana-Farber Cancer Institute

   See if you can join NCT06040125 on ClinicalTrials.gov

2. Study of HLD-0915 (JNJ-101556143) in Patients With Metastatic Prostate Cancer

   Assessment of the safety and efficacy of HLD-0915 (JNJ-101556143) in patients with metastatic prostate cancer who have progressed on prior systemic therapies, with further evaluation in additional prostate cancer populations.

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Dana Farber Mass General Brigham Cancer Care Inc, Boston, Massachusetts

   Locations

   18 in total

   Run by

   Janssen Research & Development, LLC

   See if you can join NCT06800313 on ClinicalTrials.gov

3. Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

   The main purpose of this study is to assess the safety and tolerability of AZD0516 as monotherapy and/or in combination with other anti-cancer agents for treatment of metastatic prostate cancer.

   Stage

   Phase 1

   Ages

   18 to 130

   Site

   Research Site, Boston, Massachusetts

   Locations

   52 in total

   Run by

   AstraZeneca

   See if you can join NCT07181161 on ClinicalTrials.gov

4. Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer

   This is a prospective, open-label, multi-center seamless phase II to phase III randomized clinical trial designed to compare SST with or without PET-directed local therapy in improving the castration-resistant prostate cancer-free survival (CRPC-free survival) for Veterans with oligometastatic pros…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts

   Locations

   20 in total

   Run by

   VA Office of Research and Development

   See if you can join NCT04787744 on ClinicalTrials.gov

5. Study of AZD0754 in Participants With Metastatic Prostate Cancer

   The purpose of this study is to evaluate the safety, tolerability, and antitumour activity of AZD0754 CAR T-cell therapy in participants with metastatic prostate cancer.

   Stage

   Phase 1

   Ages

   18 to 130

   Site

   Research Site, Boston, Massachusetts

   Locations

   15 in total

   Run by

   AstraZeneca

   See if you can join NCT06267729 on ClinicalTrials.gov

6. Pilot Study for Detection of PSMA-Low CRPC-NE Tumors With Fluciclovine PET/CT

   This research study is studying a positron emission tomography (PET) agent called 18F-fluciclovine to evaluate how well 18F-fluciclovine-PET scans determine the extent of advanced prostate cancer that either has low prostate-specific membrane antigen (PSMA) expression or has neuroendocrine features…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Dana Farber Cancer Institute, Boston, Massachusetts

   Locations

   2 in total

   Run by

   Brigham and Women's Hospital

   See if you can join NCT06062745 on ClinicalTrials.gov