Metastatic Malignant Solid Neoplasm Clinical Trials in Los Angeles, California

6 studies are recruiting for metastatic malignant solid neoplasm in Los Angeles, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

   This ComboMATCH patient screening trial is the gateway to a coordinated set of clinical trials to study cancer treatment directed by genetic testing. Patients with solid tumors that have spread to nearby tissue or lymph nodes (locally advanced) or have spread to other places in the body (advanced) …

   Stage

   Phase 2

   Ages

   Any age

   Site

   The Angeles Clinic and Research Institute - West Los Angeles Office, Los Angeles, California

   Locations

   482 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT05564377 on ClinicalTrials.gov

2. Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

   This phase II trial tests whether ZEN003694 (ZEN-3694) in combination with talazoparib works to shrink tumors in patients with solid tumors that are unlikely to be cured or controlled with treatment and that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Keck Medicine of USC Koreatown, Los Angeles, California

   Locations

   36 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT05327010 on ClinicalTrials.gov

3. Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

   This phase I trial tests the safety, side effects, and best dose of novobiocin in treating cancer patients with alterations in deoxyribonucleic acid (DNA) repair genes. Novobiocin is an antibiotic that blocks the activity of a protein called DNA polymerase theta, which helps repair DNA that has bec…

   Stage

   Phase 1

   Ages

   18 and older

   Site

   Los Angeles General Medical Center, Los Angeles, California

   Locations

   23 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT05687110 on ClinicalTrials.gov

4. Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

   This phase I trial tests the safety, side effects, and best dose of ZEN003694 when given together with abemaciclib in treating patients with NUT carcinoma, breast cancer or other solid tumors that have spread from where it first started (primary site) to other places in the body (metastatic) or can…

   Stage

   Phase 1

   Ages

   12 and older

   Site

   Keck Medicine of USC Koreatown, Los Angeles, California

   Locations

   7 in total

   Run by

   National Cancer Institute (NCI)

   See if you can join NCT05372640 on ClinicalTrials.gov

5. Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors

   This phase I trial studies the side effects and best dose of modified immune cells (IL13Ralpha2 CAR T cells) after a chemotherapy conditioning regimen for the treatment of patients with stage IIIC or IV melanoma or solid tumors that have spread to other places in the body (metastatic). The study ag…

   Stage

   Phase 1

   Ages

   18 to 75

   Site

   UCLA / Jonsson Comprehensive Cancer Center, Los Angeles, California

   Locations

   3 in total

   Run by

   Anusha Kalbasi

   See if you can join NCT04119024 on ClinicalTrials.gov

6. Collection and Storage of Tissue and Blood Samples From Patients With Cancer

   This study collects and stores tissue and blood samples from patients with cancer. Collecting and storing samples of tissue and blood from patients with cancer to study in the laboratory may help scientists create new and better models to learn about cancer and to test new cancer drugs.

   Stage

   Not phased

   Ages

   0 and older

   Site

   USC / Norris Comprehensive Cancer Center, Los Angeles, California

   Locations

   140 in total

   Run by

   National Cancer Institute LAO

   See if you can join NCT02474160 on ClinicalTrials.gov