Metastatic Colorectal Cancer Clinical Trials in Boston, Massachusetts

6 studies are recruiting for metastatic colorectal cancer in Boston, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

Search these by distance from you

Studies now recruiting

  1. A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer

    CRC is the third most common type of cancer diagnosed worldwide with developed countries at highest risk. The purpose of this study is to assess adverse events and change in disease activity when telisotuzumab adizutecan is given in combination with oxaliplatin, fluorouracil (5FU), leucovorin (LV) …

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Dana-Farber Cancer Institute /ID# 270624, Boston, Massachusetts
    Locations
    71 in total
    Run by
    AbbVie

    See if you can join NCT06820463 on ClinicalTrials.gov

  2. A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)

    This open-label, exploratory study is designed to evaluate the safety and efficacy of targeted therapies or immunotherapy as single agents or combinations, in participants with metastatic colorectal cancer (mCRC) whose tumors are biomarker positive as per treatment arm-specific definition. Eligible…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    84 in total
    Run by
    Hoffmann-La Roche

    See if you can join NCT04929223 on ClinicalTrials.gov

  3. Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial

    This research study is a randomized controlled trial that will observe changes in microbiome activity, changes in chemotherapy toxicity, and any changes in treatment outcomes between two groups of participants undergoing chemotherapy with either early-stage or metastatic colorectal cancer. The name…

    Stage
    Not phased
    Ages
    18 to 50
    Site
    Dana Farber Cancer Institute, Boston, Massachusetts
    Run by
    Dana-Farber Cancer Institute

    See if you can join NCT06202183 on ClinicalTrials.gov

  4. Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

    First in human study to evaluate the safety, tolerability, and pharmacokinetics (PK) of BBO-10203, a PI3Kα:RAS breaker, alone and in combination with other anti-cancer agents in patients with advanced solid tumors.

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Locations
    44 in total
    Run by
    TheRas, Inc., d/b/a BBOT (BridgeBio Oncology Therapeutics)

    See if you can join NCT06625775 on ClinicalTrials.gov

  5. A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer

    The main purpose of this study is to evaluate the safety and efficacy of novel study interventions and combinations in participants with Colorectal Cancer (CRC).

    Stage
    Phase 2
    Ages
    18 to 130
    Site
    Research Site, Boston, Massachusetts
    Locations
    76 in total
    Run by
    AstraZeneca

    See if you can join NCT06792695 on ClinicalTrials.gov

  6. A Multicenter Phase 1b/2 Study of Adagrasib, Cetuximab, and Cemiplimab for Metastatic Colorectal Cancer Harboring KRAS G12C Mutations

    To learn if the drug combination of adagrasib, cetuximab, and cemiplimab can help to control metastatic CRC with KRAS G12C mutations.

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Massachusetts General Hospital Cancer Center, Boston, Massachusetts
    Locations
    2 in total
    Run by
    M.D. Anderson Cancer Center

    See if you can join NCT06412198 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.