Major Depressive Disorder Clinical Trials in Worcester, Massachusetts

3 studies are recruiting for major depressive disorder in Worcester, Massachusetts right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

    X-NOVA3 is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of azetukalner as a monotherapy in adult participants diagnosed with Major Depressive Disorder (MDD)

    Stage
    Phase 3
    Ages
    18 to 74
    Site
    Vitalix Clinical, Inc, Worcester, Massachusetts
    Locations
    50 in total
    Run by
    Xenon Pharmaceuticals Inc.

    See if you can join NCT07076407 on ClinicalTrials.gov

  2. A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)

    A Phase 3 Double-blind, Placebo-controlled Study (Part A) with an Open-label Extension (Part B) Evaluating DT120 Compared to Placebo in Major Depressive Disorder - Ascend

    Stage
    Phase 3
    Ages
    18 to 74
    Site
    Vitalix Clinical, Worcester, Massachusetts
    Locations
    30 in total
    Run by
    Definium Therapeutics US, Inc.

    See if you can join NCT07592689 on ClinicalTrials.gov

  3. A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

    The goal of this clinical trial is to learn if zelquistinel works to treat depression in adults. It will also learn about the safety of zelquistinel. The main questions it aims to answer are: Does zelquistinel reduce depression scores in participants compared to participants who take a placebo (a l…

    Stage
    Phase 2
    Ages
    18 to 64
    Site
    Vitalix Clinical, Worcester, Massachusetts
    Locations
    32 in total
    Run by
    Syndeio Biosciences, Inc

    See if you can join NCT07115329 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.