Major Depressive Disorder Clinical Trials in Columbus, Ohio

4 studies are recruiting for major depressive disorder in Columbus, Ohio right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder

   This is a multicenter, randomized, double-blind, placebo-controlled parallel-group, fixed-dose study in patients with a primary diagnosis of MDD according to criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) who have an inadequate response to ongoing ADT.

   Stage

   Phase 3

   Ages

   18 to 65

   Site

   The Ohio State University, Columbus, Ohio

   Locations

   69 in total

   Run by

   Intra-Cellular Therapies, Inc.

   See if you can join NCT05850689 on ClinicalTrials.gov

2. A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety

   The goal of this study is to learn how psychedelics may help symptoms of depression and anxiety. Participants with major depressive disorder experiencing symptoms of depression and anxiety will receive one dose of either a drug related to psilocybin or a placebo. Assessments include interviews, sel…

   Stage

   Phase 2

   Ages

   21 to 65

   Site

   The Ohio State University Department of Psychiatry, Columbus, Ohio

   Run by

   Ohio State University

   See if you can join NCT06820723 on ClinicalTrials.gov

3. A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder

   Major depressive disorder (MDD; depression) is a mood disorder that causes a continued feeling of sadness and loss of interest. It is a common and serious illness that can cause both emotional and physical symptoms such as feelings of sadness, irritability, not being able to focus on activities, ti…

   Stage

   Phase 2

   Ages

   18 to 65

   Site

   OSU Psychiatry Department /ID# 277529, Columbus, Ohio

   Locations

   33 in total

   Run by

   AbbVie

   See if you can join NCT07276997 on ClinicalTrials.gov

4. Mechanisms of Rumination Change in Adolescent Depression

   This study will evaluate whether a newer treatment, rumination-focused cognitive behavioral treatment, which includes mindfulness and can be used to reduce ruminative habits, change ways in which key brain regions interact with each other (e.g.., often called connectivity), and whether these change…

   Stage

   Not phased

   Ages

   14 to 17

   Site

   Nationwide Children's Hospital, Columbus, Ohio

   Locations

   3 in total

   Run by

   Ohio State University

   See if you can join NCT03859297 on ClinicalTrials.gov