Major Depressive Disorder Clinical Trials in Birmingham, Alabama

4 studies are recruiting for major depressive disorder in Birmingham, Alabama right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

   The goal of this clinical trial is to learn if zelquistinel works to treat depression in adults. It will also learn about the safety of zelquistinel. The main questions it aims to answer are: Does zelquistinel reduce depression scores in participants compared to participants who take a placebo (a l…

   Stage

   Phase 2

   Ages

   18 to 64

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   34 in total

   Run by

   Syndeio Biosciences, Inc

   See if you can join NCT06547489 on ClinicalTrials.gov

2. Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents

   This study is dedicated to help identify biomarkers for depression and suicide. The purpose of the study is to better understand these links to improve medical and psychiatric care in the future. This research is also to test the effects of standard treatment of depression on improvement in depress…

   Stage

   Not phased

   Ages

   10 to 24

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   2 in total

   Run by

   University of Alabama at Birmingham

   See if you can join NCT05437588 on ClinicalTrials.gov

3. MicroRNA Correlates of Childhood Maltreatment and Suicidality

   This is a research study to find out if childhood trauma and stress are associated with depression or suicidal risk. The study will assess the effects of both short-term and long-term stress on biomarker (e.g. miRNA [MiRNA]) levels. miRNAs are a type of RNA (genetic material that is translated into…

   Stage

   Not phased

   Ages

   18 to 60

   Site

   University of Alabama at Birmingham, Birmingham, Alabama

   Locations

   2 in total

   Run by

   University of Alabama at Birmingham

   See if you can join NCT04923685 on ClinicalTrials.gov

4. Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

   The goal of this clinical trial is to learn if ABX-002 added to an existing antidepressant treatment will benefit depression symptoms in adults with moderate to severe major depressive disorder who have had an inadequate response to their antidepressant. This is a double-blind, placebo-controlled, …

   Stage

   Phase 2

   Ages

   18 to 65

   Site

   Autobahn Site #131, Birmingham, Alabama

   Locations

   50 in total

   Run by

   Autobahn Therapeutics, Inc.

   See if you can join NCT06633016 on ClinicalTrials.gov