Major Depressive Disorder (MDD) Clinical Trials in Philadelphia, Pennsylvania

3 studies are recruiting for major depressive disorder (mdd) in Philadelphia, Pennsylvania right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of Ketamine

    In the treatment of Major Depressive Disorder (MDD), ketamine can produce rapid but short-lasting improvements in mood. In order to develop a new generation of treatments with rapid and sustained efficacy, a better understanding of the mechanism of action is urgently needed. One candidate mechanism…

    Stage
    EARLY_Phase 1
    Ages
    25 to 65
    Site
    University of Pennsylvania, Philadelphia, Pennsylvania
    Run by
    University of Pennsylvania

    See if you can join NCT06788249 on ClinicalTrials.gov

  2. A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

    The purpose of this study is to determine the efficacy, safety and tolerability of CYB003 compared to matching placebo as adjunctive treatment in patients with MDD. For more information about the EMBRACE study, including participating study locations, and to register your interest in learning more …

    Stage
    Phase 3
    Ages
    18 to 85
    Site
    Adams Clinical Philadelphia, Philadelphia, Pennsylvania
    Locations
    69 in total
    Run by
    Cybin IRL Limited

    See if you can join NCT06793397 on ClinicalTrials.gov

  3. Neurofeedback to Treat Depression - 2

    This study tests the efficacy of a new psychotherapeutic strategy for reducing negative attention bias (and therefore depression severity) in participants with MDD. This real-time fMRI neurofeedback therapy uses cloud-based pattern classification to decode a patient's attentional state and dynamica…

    Stage
    Not phased
    Ages
    18 to 65
    Site
    Center for Neuromodulation in Depression and Stress, Philadelphia, Pennsylvania
    Run by
    University of Pennsylvania

    See if you can join NCT07159061 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.