Major Depressive Disorder (MDD) Clinical Trials in Orange, California

4 studies are recruiting for major depressive disorder (mdd) in Orange, California right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response

    The goal of this clinical trial is to learn if ACP-211 can help treat adults with major depressive disorder (MDD) who have not improved with antidepressant therapy (ADT), including those with treatment resistant depression (TRD). The main questions the study aims to answer are: * Does ACP-211 work …

    Stage
    Phase 2
    Ages
    18 to 65
    Site
    PNS Clinical Research LLC dba ATP Clinical Research, Orange, California
    Locations
    26 in total
    Run by
    ACADIA Pharmaceuticals Inc.

    See if you can join NCT07284667 on ClinicalTrials.gov

  2. A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder

    The purpose of this study is to determine the efficacy, safety and tolerability of CYB003 compared to matching placebo as adjunctive treatment in patients with MDD. For more information about the EMBRACE study, including participating study locations, and to register your interest in learning more …

    Stage
    Phase 3
    Ages
    18 to 85
    Site
    ATP Clinical Research, Orange, California
    Locations
    69 in total
    Run by
    Cybin IRL Limited

    See if you can join NCT06793397 on ClinicalTrials.gov

  3. A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

    The goal of this clinical trial is to learn if a drug called TNX-102 SL works to treat moderate to severe major depressive disorder in adults. It will also learn about the safety of TNX-102 SL. The main questions it aims to answer are: Does TNX-102 SL improve depression symptoms according to a depr…

    Stage
    Phase 2
    Ages
    18 and older
    Site
    Nrc Research Institute, Orange, California
    Locations
    25 in total
    Run by
    Tonix Pharmaceuticals, Inc.

    See if you can join NCT07621237 on ClinicalTrials.gov

  4. Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

    The purpose of this study is to determine the efficacy and safety of milsaperidone compared to placebo as adjunctive therapy in patients with Major Depressive Disorder

    Stage
    Phase 3
    Ages
    18 to 65
    Site
    Vanda Investigational Site, Orange, California
    Locations
    38 in total
    Run by
    Vanda Pharmaceuticals

    See if you can join NCT06830044 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.