Lupus Nephritis Clinical Trials in Miami, Florida

5 studies are recruiting for lupus nephritis in Miami, Florida right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. VIBRANT: VIB4920 for Active Lupus Nephritis

   This is a multi-center double-blind placebo controlled clinical trial evaluating the efficacy of VIB4920 combined with mycophenolate mofetil (MMF) and prednisone in achieving a renal response in participants with active lupus nephritis (LN).

   Stage

   Phase 2

   Ages

   18 and older

   Site

   University of Miami Miller School of Medicine: Nephrology & Hypertension Division, Miami, Florida

   Locations

   17 in total

   Run by

   National Institute of Allergy and Infectious Diseases (NIAID)

   See if you can join NCT05201469 on ClinicalTrials.gov

2. A Phase 2, Open-Label, Single-Arm Trial of FT819 in Participants With Lupus Nephritis

   The primary objective of this trial is to evaluate the efficacy and safety of FT819, comprised of allogeneic T cells that express a CD19-targeted CAR, following bendamustine administration in participants with refractory moderate-to-severe lupus nephritis, as assessed by the proportion of participa…

   Stage

   Phase 2

   Ages

   12 to 70

   Site

   Miami Dermatology and Laser Research, Miami, Florida

   Locations

   12 in total

   Run by

   Fate Therapeutics

   See if you can join NCT07570862 on ClinicalTrials.gov

3. A Phase 1/2 Study of NKX019 in Subjects With Autoimmune Disease (Ntrust-1)

   This is a Phase 1/2, open-label, multi-center, multi-cohort, non-randomized dose escalation and dose expansion basket study to determine the safety and tolerability of NKX019 (allogeneic CAR NK cells targeting CD19) in participants with autoimmune diseases.

   Stage

   Phase 1

   Ages

   18 to 75

   Site

   Nkarta Investigational Site, Miami, Florida

   Locations

   19 in total

   Run by

   Nkarta, Inc.

   See if you can join NCT06557265 on ClinicalTrials.gov

4. A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease

   This is a phase 1 study designed to evaluate the safety, pharmacokinetics (PK), and anti-B-cell activity of FT819 following treatment with or without auxiliary medicinal product (AMP) in participants with moderate-to-severe active systemic lupus erythematosus (SLE) with or without nephritis, antine…

   Stage

   Phase 1

   Ages

   12 to 70

   Site

   Nicklaus Children's Hospital, Miami, Florida

   Locations

   21 in total

   Run by

   Fate Therapeutics

   See if you can join NCT06308978 on ClinicalTrials.gov

5. Lupus Landmark Study: A Prospective Registry and Biorepository

   The purpose of the registry and biorepository is to provide a mechanism to store clinical data, linked biospecimens and molecular data to support the conduct of future research on Systemic Lupus Erythematosus (SLE), including Lupus Nephritis (LN).

   Stage

   Not phased

   Ages

   18 to 110

   Site

   University of Miami, Miami, Florida

   Locations

   25 in total

   Run by

   Lupus Research Alliance

   See if you can join NCT05934149 on ClinicalTrials.gov