Lupus Nephritis Clinical Trials in Aurora, Colorado

4 studies are recruiting for lupus nephritis in Aurora, Colorado right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. VIBRANT: VIB4920 for Active Lupus Nephritis

    This is a multi-center double-blind placebo controlled clinical trial evaluating the efficacy of VIB4920 combined with mycophenolate mofetil (MMF) and prednisone in achieving a renal response in participants with active lupus nephritis (LN).

    Stage
    Phase 2
    Ages
    18 and older
    Site
    University of Colorado School of Medicine: Division of Rheumatology, Aurora, Colorado
    Locations
    17 in total
    Run by
    National Institute of Allergy and Infectious Diseases (NIAID)

    See if you can join NCT05201469 on ClinicalTrials.gov

  2. The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

    The study is a 1-year 2-part double-blinded placebo controlled 2-arm clinical trial. Treatment arms are (1) MMF dosed as per body-surface area (MMFBSA; 600mg/m2 body surface area per dose about every 12 hours) and (2) pharmacokinetically-guided precision-dosing of MMF (MMFPK; MMF dosed twice daily …

    Stage
    Phase 2
    Ages
    8 to 20
    Site
    Children's Hospital Colorado, Aurora, Colorado
    Locations
    19 in total
    Run by
    Children's Hospital Medical Center, Cincinnati

    See if you can join NCT05538208 on ClinicalTrials.gov

  3. A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescents With Active Class III or IV Lupus Nephritis and the Safety and PK of Obinutuzumab in Pediatric Participants

    This phase II, randomized, double-blind, placebo-controlled study is designed to evaluate the safety, efficacy and pharmacokinetics (PK) of obinutuzumab in adolescent participants (AP) aged 12 to less than 18 with biopsy-confirmed proliferative lupus nephritis (LN). It will also evaluate open label…

    Stage
    Phase 2
    Ages
    5 to 17
    Site
    Children's Hospital Colorado, Anchutz Medical Campus, Aurora, Colorado
    Locations
    43 in total
    Run by
    Hoffmann-La Roche

    See if you can join NCT05039619 on ClinicalTrials.gov

  4. Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

    The overall purpose of this two-part study is to evaluate the efficacy, safety and tolerability of iptacopan (LNP023) in addition to standard of care treatment.

    Stage
    Phase 2
    Ages
    18 to 100
    Site
    University of Colorado Denver, Aurora, Colorado
    Locations
    103 in total
    Run by
    Novartis Pharmaceuticals

    See if you can join NCT05268289 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.