Inflammatory Bowel Diseases Clinical Trials

25 studies are recruiting for inflammatory bowel diseases in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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New York, New York 6 Boston, Massachusetts 5 Atlanta, Georgia 3 Chapel Hill, North Carolina 3 Durham, North Carolina 3 Miami, Florida 3 Philadelphia, Pennsylvania 3 St Louis, Missouri 3

Studies now recruiting

  1. Duloxetine in Inflammatory Bowel Diseases

    This open-label, prospective, single-arm pilot study investigates the use of duloxetine, a central neuromodulator, for improving psychological distress and functional impairment in adults with inflammatory bowel disease (IBD). The study focuses on patient-reported outcomes related to anxiety, depre…

    Stage
    Phase 2
    Ages
    24 and older
    Site
    University of Pennsylvania, Philadelphia, Pennsylvania
    Run by
    University of Pennsylvania

    See if you can join NCT07431606 on ClinicalTrials.gov

  2. A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

    This is a Phase 2, multicenter, proof-of-concept platform study in adult participants with moderately to severely active ulcerative colitis (UC). The primary goal of the study is to assess the efficacy and safety of multiple interventions following intravenous (IV) induction and subcutaneous (SC) m…

    Stage
    Phase 2
    Ages
    18 to 75
    Site
    Site 024, Canoga Park, California
    Locations
    276 in total
    Run by
    Spyre Therapeutics, Inc.

    See if you can join NCT07012395 on ClinicalTrials.gov

  3. Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cell Intravenous Infusion for Crohn's Disease or Ulcerative Colitis

    This trial will study the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Crohn's Disease or Ulcerative Colitis

    Stage
    Phase 1
    Ages
    Any age
    Site
    Prodromos Stem Cell Institute, Naples, Florida
    Locations
    2 in total
    Run by
    The Foundation for Orthopaedics and Regenerative Medicine

    See if you can join NCT05003947 on ClinicalTrials.gov

  4. A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

    This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of 3 active dose regimens of MORF-057 in adult study participants with moderately to severely active Crohn's disease (CD).

    Stage
    Phase 2
    Ages
    18 to 85
    Site
    Gastro Care Institute, Lancaster, California
    Locations
    225 in total
    Run by
    Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)

    See if you can join NCT06226883 on ClinicalTrials.gov

  5. A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

    The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD). The study will last about 172 weeks and may include up to 44 visits. Additional treatment may be available to participants via a Contin…

    Stage
    Phase 3
    Ages
    2 to 19
    Site
    UCSF Medical Center at Mission Bay, San Francisco, California
    Locations
    69 in total
    Run by
    Eli Lilly and Company

    See if you can join NCT04844606 on ClinicalTrials.gov

  6. Feasibility of a Wireless Thermal Capsule Endoscopy to Detect Gastrointestinal Thermal Variance

    The goal of this research is to learn how a new device called the wireless thermal capsule (WTC) can collect thermal data to help see diseases that happen in the gastrointestinal (GI) tract, such as Crohn's Disease.

    Stage
    Not phased
    Ages
    18 to 75
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Run by
    Massachusetts General Hospital

    See if you can join NCT07033208 on ClinicalTrials.gov

  7. Proof of Concept Study Evaluating the Efficacy and Safety of ATH-063 Treatment in Patients With Relapsed/Refractory Moderately to Severely Active Ulcerative Colitis (UC)

    The primary objective of this trial is to evaluate the clinical efficacy of ATH-063 in participants with biologic/advanced therapy relapsed/refractory moderately to severely active UC.

    Stage
    Phase 2
    Ages
    18 to 75
    Site
    Miami Clinical Research, Miami, Florida
    Locations
    4 in total
    Run by
    Athos Therapeutics Inc

    See if you can join NCT07513181 on ClinicalTrials.gov

  8. Observational Pharmaco-Epidemiology Research & Analysis

    Greater advances are needed in two separate but related areas in healthcare: 1) the Clinical Decision Support Systems that complement the EHR use in support of routine patient care, population management and disease management; and 2) the use of the point-of-care observational data from the provide…

    Stage
    Not phased
    Ages
    0 and older
    Site
    Epividian, Durham, North Carolina
    Run by
    Epividian

    See if you can join NCT03813862 on ClinicalTrials.gov

  9. Testing the Role of Anti-fungal Therapy in Improving the Response to Therapies for Crohn's Disease

    The goal of this clinical trial is to learn about the effects of fluconazole in patients who plan to start or are currently undergoing standard of care treatment and plan to dose-escalate an IL-23 therapy for their Crohn's disease. The main question it aims to assess is whether or not patient respo…

    Stage
    Phase 3
    Ages
    18 and older
    Site
    Weill Cornell Medicine, New York, New York
    Run by
    Weill Medical College of Cornell University

    See if you can join NCT06274554 on ClinicalTrials.gov

  10. BOOM-IBD2 Pivotal Clinical Trial

    Ulcerative colitis is a long-lasting condition that causes swelling and sores in the large intestine. This study tests whether a small device placed under the skin can help reduce bowel urgency in people with ulcerative colitis. The investigational device sends mild signals to a nerve near the tail…

    Stage
    Not phased
    Ages
    18 to 85
    Site
    Gastroenterology Medical Clinic (Objective Health), Folsom, California
    Locations
    19 in total
    Run by
    Boomerang Medical

    See if you can join NCT06571669 on ClinicalTrials.gov

  11. Social Determinants of Health, Medication Use, and Quality of Life in Inflammatory Bowel Disease

    Optimizing health related-quality of life (HRQoL) for patients with inflammatory bowel disease (IBD), who often experience a relapsing disease course, is an essential component of care. Improving IBD disease control is linked to increased health-related quality of life. Even as many effective pharm…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Icahn School of Medicine at Mount Sinai, New York, New York
    Locations
    2 in total
    Run by
    Montefiore Medical Center

    See if you can join NCT06266663 on ClinicalTrials.gov

  12. Virtual Reality (VR) -Directed Brain Gut Behavioral Treatment (BGBT) for Inflammatory Bowel Disease (IBD) Inpatients

    The research is studying virtual reality (VR)-directed brain-gut behavioral therapy (BGBT) as a pain treatment option for hospitalized patients with inflammatory bowel disease (IBD). This study is being done to learn if VR-directed BGBT is feasible and acceptable for patients with IBD in addressing…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Michigan, Ann Arbor, Michigan
    Run by
    University of Michigan

    See if you can join NCT06188793 on ClinicalTrials.gov

  13. Developing a Self-Management Intervention to Improve Health Outcomes for Patients With Inflammatory Bowel Disease

    This research is studying whether changing an individual's behaviors may have an impact as a treatment or outcome for inflammatory bowel disease. This research will increase the understanding of the role of a self-management program in improving health and health-related quality of life for patient…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Micigan, Ann Arbor, Michigan
    Run by
    University of Michigan

    See if you can join NCT07456566 on ClinicalTrials.gov

  14. Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)

    This is a prospective observational study collecting long-term clinical data and samples for research in pediatric inflammatory bowel disease (IBD) patients with gut inflammation and a control cohort of pediatric patients with disorders of the brain-gut interactions (DBGI) with no detectable gut in…

    Stage
    Not phased
    Ages
    6 to 21
    Site
    Seattle Children's Hospital, Seattle, Washington
    Run by
    Seattle Children's Hospital

    See if you can join NCT06315179 on ClinicalTrials.gov

  15. COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)

    The purpose of the study is to compare the clinical effectiveness and safety of newer inflammatory bowel disease (IBD) medications in anti-tumor necrosis factor (TNF) refractory patients with pediatric IBD (PIBD). Refractory means that there was no clinical response to anti-tumor necrosis factor (T…

    Stage
    Not phased
    Ages
    1 to 18
    Site
    University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
    Locations
    4 in total
    Run by
    University of North Carolina, Chapel Hill

    See if you can join NCT07198113 on ClinicalTrials.gov

  16. Therapeutic Endpoint in Pediatric IBD Conditions

    The purpose of this clinical study is the development of physiologic endpoint of inflammation in pediatric patients diagnosed with inflammatory bowel disease (IBD), specifically subtypes Crohn's disease (CD) and ulcerative colitis (UC). The novel medical device evaluates the patient's sensory respo…

    Stage
    Not phased
    Ages
    6 to 21
    Site
    Children's National Health System, Washington D.C., District of Columbia
    Run by
    Children's National Research Institute

    See if you can join NCT06065228 on ClinicalTrials.gov

  17. Heart Rate Variability and Inflammatory Bowel Disease

    The goals of this study are to test the effectiveness of a virtually delivered, group-based coping skills treatment program incorporating heart rate variability biofeedback to target autonomic dysfunction in youth diagnosed with inflammatory bowel disease (IBD). The investigators will enroll partic…

    Stage
    Not phased
    Ages
    13 to 18
    Site
    Atlanta Metropolitan Area, Atlanta, Georgia
    Locations
    3 in total
    Run by
    Emory University

    See if you can join NCT06537258 on ClinicalTrials.gov

  18. Pre-operative Nutrition for Elective Resection Surgery in Inflammatory Bowel Disease

    This study aims to determine if improved risk stratification tools and interventions to mitigate malnutrition reduce postoperative risk in patients undergoing elective or emergent resection surgery for inflammatory bowel disease (IBD), and if adding immune modulation nutrition improves surgical out…

    Stage
    Not phased
    Ages
    18 and older
    Site
    NYU Langone Health, New York, New York
    Run by
    NYU Langone Health

    See if you can join NCT06309017 on ClinicalTrials.gov

  19. The 1200 Patients Project: Studying the Implementation of Clinical Pharmacogenomic Testing

    The purpose of this study is to collect DNA samples from patients undergoing routine care at the University of Chicago. These samples will be tested for differences in genes that may suggest greater risk of side effects or chance of increased benefit from certain medications. The results will be ma…

    Stage
    Not phased
    Ages
    18 and older
    Site
    University of Chicago Medical Center, Chicago, Illinois
    Run by
    University of Chicago

    See if you can join NCT01280825 on ClinicalTrials.gov

  20. Fermented Food-Supplemented Diet in Ulcerative Colitis

    The purpose of this study is to see how a diet that supplements fermented foods effects inflammation and quality of life in patients with mild to moderate Ulcerative Colitis (UC). There is a paucity of research and an enormous need for better understanding of diet and intestinal inflammation. Ferme…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Stanford University, Palo Alto, California
    Run by
    Stanford University

    See if you can join NCT04401605 on ClinicalTrials.gov

  21. Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study

    PSC is a liver disease that has no medical cure. Patients with PSC are at a greatly increased risk of cancer and infection. Additionally, many patients require a liver transplant. Progress towards a cure has been severely limited by an incomplete understanding of why patients develop PSC. The inves…

    Stage
    EARLY_Phase 1
    Ages
    18 to 80
    Site
    Stanford University, Stanford, California
    Run by
    Stanford University

    See if you can join NCT05912387 on ClinicalTrials.gov

  22. Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility

    The aim of this study is to develop and assess the feasibility and effect of a web-based, personalized risk-estimation for Crohn's disease (PRE-Crohn's) tool on behaviors and biomarkers associated with risk for Crohn's disease in unaffected first-degree relatives of patients with inflammatory bowel…

    Stage
    Not phased
    Ages
    14 and older
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Run by
    Massachusetts General Hospital

    See if you can join NCT05332639 on ClinicalTrials.gov

  23. A Study for Imaging the Lower Gastrointestinal Tract Using a Retro-TCE Capsule

    The investigators have developed an inexpensive tool to take pictures in the lower GI tract without sedation and to look for signs of disease. The tool is a capsule, about the size of a fish oil or multi-vitamin supplement, attached to a string. The capsule and string are connected to a motor to al…

    Stage
    Not phased
    Ages
    18 to 75
    Site
    Massachusetts General Hospital, Boston, Massachusetts
    Run by
    Massachusetts General Hospital

    See if you can join NCT07219537 on ClinicalTrials.gov

  24. VNS Prospective Neuromodulation of Immune and Gastrointestinal Systems

    Vagal nerve stimulation is a neurosurgical procedure consisting of implantation of an impulse generator battery with leads placed into the vagus nerve in the neck. This procedure was FDA approved for epilepsy in the 1990s and is commonly performed as an outpatient surgery. The mechanism of action i…

    Stage
    Not phased
    Ages
    0 to 60
    Site
    University of Louisville, Louisville, Kentucky
    Locations
    4 in total
    Run by
    University of Louisville

    See if you can join NCT03953768 on ClinicalTrials.gov

  25. Registry and Biorepository for IBD in Central Texas

    This is a prospective, non-interventional registry and biorepository for patients with IBD. Longitudinal follow-up data is collected from both patients and their treating gastroenterologist during routine clinical encounters. The biorepository will consist of prospective collection of blood samples…

    Stage
    Not phased
    Ages
    18 to 100
    Site
    Dell Medical School, UT Austin, Austin, Texas
    Run by
    University of Texas at Austin

    See if you can join NCT04617184 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.