Infertility Clinical Trials

23 studies are recruiting for infertility in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy

    Background: Medical advances have improved survival rates for many cancers and other illnesses. This means that more people are coping with the long-term effects of these treatments. Some treatments can cause female infertility. Ovarian tissue cryopreservation (OTC) may help. Before undergoing a tr…

    Stage
    Not phased
    Ages
    4 to 35
    Site
    National Institutes of Health Clinical Center, Bethesda, Maryland
    Run by
    Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
  2. Sperm Preparation Prior to Intrauterine Insemination Study

    This is a randomized controlled trial comparing density gradient centrifugation and microfluidic sperm sorting in patients undergoing intrauterine insemination to evaluate cumulative pregnancy outcomes.

    Stage
    Not phased
    Ages
    18 and older
    Site
    UCSF Center for Reproductive Health, San Francisco, California
    Run by
    University of California, San Francisco
  3. Hormone-free Antral Retrieval for Viable Embryo Storage & Transfer

    This study is testing whether eggs can be collected from small follicles without using the usual ovarian stimulation medications. Participants will have up to three egg retrieval procedures. The eggs collected during each retrieval will be matured in the laboratory using the CAPA-IVM (Capacitation …

    Stage
    Not phased
    Ages
    18 to 35
    Site
    CARE Fertility Texas, Bedford, Texas
    Run by
    Kevin Doody
  4. Non-Euploid Embryo Transfer (NEET) Registry

    The NEET Registry is a registry to track and study the outcomes of non-euploid embryo transfers (NEET) in The Prelude Network

    Stage
    Not phased
    Ages
    Any age
    Site
    Inception Fertility Research Institute, Houston, Texas
    Run by
    Inception Fertility Research Institute, LLC
  5. The Hysterosalpingogram (HSG) Experience And Tubal Spasm (HEAT) Study

    The hysterosalpingogram (HSG) is the gold standard of assessing fallopian tube patency and involves the placement of a transcervical catheter to allow for instillation of radio-opaque dye into the uterine cavity and fallopian tubes which are then imaged with abdominal x-ray. A common side effect of…

    Stage
    EARLY_Phase 1
    Ages
    18 to 45
    Site
    University of Oklahoma Health Center, Oklahoma City, Oklahoma
    Run by
    University of Oklahoma
  6. Inherited Reproductive Disorders

    Background: - During puberty, children begin to develop into adults. Problems with the hormones released during puberty can affect the reproductive system. Some people have low hormone levels that severely delay or prevent puberty. Others start puberty abnormally early. Other people may have a norm…

    Stage
    Not phased
    Ages
    0 to 120
    Site
    National Institutes of Health Clinical Center, Bethesda, Maryland
    Locations
    2 in total
    Run by
    National Institute of Environmental Health Sciences (NIEHS)
  7. GnRH for Luteal Support in IVF/ICSI/FET Cycles

    During IVF cycles an embryo is generally placed into the uterine cavity between 3 and 5 days after fertilization. For a successful pregnancy to take place, that embryo must then implant in the properly primed and staged endometrium, which subsequently must continue to develop to accommodate the gro…

    Stage
    Phase 4
    Ages
    18 to 40
    Site
    University Reproductive Associates, Hasbrouck Heights, New Jersey
    Run by
    University Reproductive Associates
  8. IntelliWell: An AI-Assisted Imaging Platform for Detection and Location of Ultra-Rare Testicular Sperm in Surgical Specimens

    This study will help determine whether an AI-assisted microwell platform (IntelliWell) can identify rare sperm cells in testicular samples found to not have sperm by conventional analysis. Instead of discarding testicular tissue which was found to be non-sperm bearing by conventional analysis the t…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Brigham and Women's Hospital, Boston, Massachusetts
    Run by
    Brigham and Women's Hospital
  9. Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors Trial

    Latrogenic infertility as a result of cancer treatment has a profound effect on long-term quality of life in survivors of reproductive-age cancers. Oocyte cryopreservation prior to cancer treatment has been associated with improved quality of life, with a potential ability to reduce long-term decis…

    Stage
    Phase 3
    Ages
    18 to 50
    Site
    University of California at San Francisco, San Francisco, California
    Run by
    University of California, San Francisco
  10. Discarded Materials Study

    Use of discarded embryos to advance laboratory expertise and technology in the area of human embryo development and assisted reproductive technologies

    Stage
    Not phased
    Ages
    18 to 65
    Site
    Reproductive Medicine Associates of new Jersey, Basking Ridge, New Jersey
    Run by
    Reproductive Medicine Associates of New Jersey
  11. Investigating Micro-Manipulation Procedures for Assisted Hatching Timing

    This study aims to assess the clinical significance of cleavage stage (Day 3) assisted hatching compared to assisted hatching at the blastocyst stage (Day 5,6,7) of embryo development at the time of trophectoderm (TE) biopsy for patients undergoing in vitro fertilization (IVF) and preimplantation g…

    Stage
    Not phased
    Ages
    18 to 42
    Site
    Reproductive Medicine Associates of New Jersey, Marlton, New Jersey
    Run by
    Reproductive Medicine Associates of New Jersey
  12. Sex Selection of Human Spermatozoa

    This study aims to demonstrate a reliable method of selecting gender specific sperm. X-bearing spermatozoa and Y-bearing spermatozoa will be identified from the density gradient layers. The selected gender specimen will then be utilized for assisted reproductive fertilization- in vitro fertilizatio…

    Stage
    Not phased
    Ages
    18 to 89
    Site
    Center for Reproductive Medicine- Weill Cornell Medicine, New York, New York
    Run by
    Weill Medical College of Cornell University
  13. Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes

    The use of machine learning techniques using an artificial intelligence tool is proposed to analyze clinical data to predict best possible IVF/ART outcomes. This tool has been utilized to accurately predict embryo quality here at Cornell. Utilizing this tool to assess objective clinical findings an…

    Stage
    Not phased
    Ages
    18 to 89
    Site
    Weill Cornell Medicine, New York, New York
    Run by
    Weill Medical College of Cornell University
  14. Gamete Treatment to Correct Fertilization Failure

    In this proposed research study, the investigators plan to assess the efficacy of gametes' (egg and sperm) treatment on fertilization as well as pre- and post-implantation embryo development.

    Stage
    Not phased
    Ages
    21 to 89
    Site
    Center fo Reproductive Medicine, New York, New York
    Run by
    Weill Medical College of Cornell University
  15. Testicular Tissue Cryopreservation in Children

    This protocol is being designed to offer testicular tissue cryopreservation to male pediatric patients (0-17 years of age) with fertility threatening medical diagnoses or facing surgery, chemotherapy or radiation therapy that may cause loss of reproductive potential.

    Stage
    Not phased
    Ages
    0 to 17
    Site
    Mayo Clinic in Rochester, Rochester, Minnesota
    Run by
    Mayo Clinic
  16. Follow-up With Preimplantation Genetic Testing Patients

    The main purpose of this study is to perform longitudinal evaluations of clinical outcomes and personal perspectives following utilization of preimplantation genetic testing (PGT). Patients indicating willingness to participate in research during informed consent to perform PGT will be eligible for…

    Stage
    Not phased
    Ages
    Any age
    Site
    Genomic Prediction Clinical Laboratory, North Brunswick, New Jersey
    Run by
    Genomic Prediction Inc.
  17. Ovarian PRP Injections for Improved Embryo Quality Using Embryo Quality Score

    Patients will have ovarian PRP treatments and embryo development will be observed using time-lapse imaging and AI software.

    Stage
    Not phased
    Ages
    18 to 47
    Site
    Generation Next Fertility, New York, New York
    Run by
    Generation Next Fertility
  18. Language Matters: Exploring the Impact of Language Concordance on Fertility Treatment Progression

    Currently, patients presenting to the Fertility and Reproductive Medicine Center meet with an English-speaking provider and communicate through an interpreter, as none of the physicians speak Spanish. However, this study PI is a native Spanish speaker and certified bilingual clinician. Thus, this s…

    Stage
    Not phased
    Ages
    18 and older
    Site
    Washington University in St Louis, St Louis, Missouri
    Run by
    Washington University School of Medicine
  19. Use of Pulsatile Intravenous FSH to Mitigate Reprometabolic Syndrome

    Hypothesis: The investigators hypothesize that pulsatile FSH intravenous administration to women with obesity will correct the Reprometabolic Syndrome (RMS) luteal deficiency phenotype. Specific Aim: To test the hypothesis that pulsatile IV administration of FSH will rescue the impaired folliculoge…

    Stage
    Phase 1
    Ages
    19 to 37
    Site
    University of Colorado Anschutz Medical Campus, Aurora, Colorado
    Run by
    University of Colorado, Denver
  20. In Vitro Maturation of Human Eggs

    CCRM Fertility, a global pioneer in fertility treatment, research and science, is seeking participants for a new study on in vitro maturation (IVM). IVM requires less hormones to stimulate the ovaries than IVF, making it more affordable than IVF with fewer side effects. Participants that qualify fo…

    Stage
    Not phased
    Ages
    Up to 38
    Site
    Colorado Center for Reproductive Medicine, Lone Tree, Colorado
    Run by
    Colorado Center for Reproductive Medicine
  21. SprmPik AI Sperm Selection Study SiD, an Assistant for Sperm Selection During Intracytoplasmic Sperm Injection in Medically Assisted Reproduction: Effect on Fertilization, Blastocyst Formation, Early Pregnancy Loss, and Consistent Practice. A Prospective Pilot Study.

    SprmPik AI Assisted Sperm Selection Study SiD, an assistant for sperm selection during intracytoplasmic sperm injection in medically assisted reproduction: effect on fertilization, blastocyst formation, early pregnancy loss, and consistent practice. A prospective pilot study.

    Stage
    Not phased
    Ages
    Any age
    Site
    Ovation Fertility Las Vegas, Las Vegas, Nevada
    Locations
    2 in total
    Run by
    Ovation Fertility
  22. Apple Women's Health Study

    This is an observational longitudinal study to advance the understanding of menstrual cycle and gynecologic health conditions including PCOS, infertility and breast cancer.The study will be hosted within the Research app(available on App Store), which allows a user to find, enroll, and participate …

    Stage
    Not phased
    Ages
    18 and older
    Site
    Harvard T.H. Chan School of Public Health, Boston, Massachusetts
    Run by
    Apple Inc.
  23. A Prospective Study of a Mosaic Embryo Transfer

    This research is a prospective study in which the purpose is to investigate the clinical outcomes following the transfer of a mosaic embryo (presence of both chromosomally normal and abnormal cells) that has been screened for preimplantation genetic testing (PGT).

    Stage
    Not phased
    Ages
    18 to 45
    Site
    Colorado Center for Reproductive Medicine, Lone Tree, Colorado
    Run by
    Colorado Center for Reproductive Medicine

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.