HER2-negative Breast Cancer Clinical Trials in Detroit, Michigan

4 studies are recruiting for her2-negative breast cancer in Detroit, Michigan right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

    The Phase 2 monotherapy portion of this study is currently enrolling and will evaluate the efficacy and safety of PC14586 (INN rezatapopt) in participants with locally advanced or metastatic solid tumors harboring a TP53 Y220C mutation. The Phase 1 portion of the study will assess the safety, toler…

    Stage
    Phase 1
    Ages
    12 and older
    Site
    Karmanos Cancer Institute, Detroit, Michigan
    Locations
    77 in total
    Run by
    PMV Pharmaceuticals, Inc

    See if you can join NCT04585750 on ClinicalTrials.gov

  2. BGB-43395 Alone or as Part of Combination Therapies in Participants With Breast Cancer and Other Advanced Solid Tumors

    This is a dose escalation and dose expansion study to compare how well BGB-43395, a selective cyclin-dependent kinase 4 (CDK4) inhibitor, works as monotherapy or in combination with fulvestrant, letrozole, or elacestrant in participants with hormone receptor positive (HR+) and human epidermal growt…

    Stage
    Phase 1
    Ages
    18 and older
    Site
    Karmanos Cancer Institute, Detroit, Michigan
    Locations
    62 in total
    Run by
    BeOne Medicines

    See if you can join NCT06120283 on ClinicalTrials.gov

  3. A Ph II Study of the TheraBionic P1 Device in Subjects With Hormone Positive Breast Cancer

    The goal of this clinical trial is to learn if the TheraBionic P1 device given to patients with advanced or metastatic HR positive, HER2 negative breast cancer who have progressed on standard of care options can affect patients survival. The main questions it aims to answer are: * will the TheraBio…

    Stage
    Not phased
    Ages
    22 and older
    Site
    Karmanos Cancer Institute, Detroit, Michigan
    Locations
    8 in total
    Run by
    Barbara Ann Karmanos Cancer Institute

    See if you can join NCT07227831 on ClinicalTrials.gov

  4. A Study of the TheraBionic P1 Device in Breast Cancer

    The goal of this clinical trial is to learn if adding cancer-specific amplitude-modulated radiofrequency electromagnetic field therapy (TheraBionic P1 device) to the treatment of resectable early-stage breast cancer will affect the pathological response.

    Stage
    Not phased
    Ages
    22 and older
    Site
    Karmanos Cancer Institute, Detroit, Michigan
    Locations
    8 in total
    Run by
    Barbara Ann Karmanos Cancer Institute

    See if you can join NCT07218432 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.