Hemophilia A Clinical Trials in Indianapolis, Indiana

3 studies are recruiting for hemophilia a in Indianapolis, Indiana right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of NXT007 in Persons With Severe or Moderate Hemophilia A

   WP44714 is a Phase I/II, open-label, non-randomized, global, multicenter trial consisting of two parts: * Part 1 is a multiple-ascending dose (MAD) study in adult and adolescent male participants with severe or moderate hemophilia A with or without factor VIII (FVIII) inhibitors. * Part 2 is a mult…

   Stage

   Phase 1

   Ages

   2 to 59

   Site

   Indiana Hemophilia & Thrombosis center, Indianapolis, Indiana

   Locations

   14 in total

   Run by

   Hoffmann-La Roche

   See if you can join NCT05987449 on ClinicalTrials.gov

2. A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A

   The purpose of this study is to evaluate the efficacy, safety, pharmacokinetics, and pharmacodynamics of NXT007 prophylaxis compared with emicizumab prophylaxis in people age 12 years and older with severe or moderate congenital hemophilia A without factor VIII (FVIII) inhibitors or with hemophilia…

   Stage

   Phase 3

   Ages

   12 and older

   Site

   Innovative Hematology, Inc., Indianapolis, Indiana

   Locations

   42 in total

   Run by

   Hoffmann-La Roche

   See if you can join NCT07416604 on ClinicalTrials.gov

3. Prevention of Bleeding in Patients With Moderate and Severe Hemophilia A Playing Sports: A Comparison Between Factor VIII and Emicizumab Prophylaxis

   Hemophilia A (HA) is a genetic bleeding disorder resulting from a deficiency or absence of factor VIII (FVIII), which is necessary in the clotting process. This disorder occurs mostly in males and in severe cases causes frequent bleeding episodes in joints and muscles which can lead to progressive …

   Stage

   Not phased

   Ages

   6 to 19

   Site

   Indiana Hemophilia & Thrombosis Center, Indianapolis, Indiana

   Locations

   10 in total

   Run by

   Wayne State University

   See if you can join NCT05022459 on ClinicalTrials.gov