Heart Failure With Preserved Ejection Fraction Clinical Trials in San Antonio, Texas

4 studies are recruiting for heart failure with preserved ejection fraction in San Antonio, Texas right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

  1. Assessment of CCM in HF With Higher Ejection Fraction

    The AIM HIGHer Clinical Trial will evaluate the safety and efficacy of Cardiac Contractility Modulation (CCM) therapy in patients with heart failure with LVEF ≥40% and ≤70%.

    Stage
    Not phased
    Ages
    18 and older
    Site
    Methodist Hospital, San Antonio, Texas
    Locations
    105 in total
    Run by
    Impulse Dynamics

    See if you can join NCT05064709 on ClinicalTrials.gov

  2. SGLT2 Inhibitors, Ketones, and Cardiovascular Benefit Research Plan

    The study team will examine the effects of SGLT2i (and SGLT2i-induced increases in plasma ketone concentrations) on skeletal muscle and cardiac ketone uptake, skeletal muscle bioenergetics, cardiopulmonary exercise capacity, and patient-reported functional outcomes.

    Stage
    EARLY_Phase 1
    Ages
    18 to 80
    Site
    University of Texas Health Science Center at San Antonio, San Antonio, Texas
    Run by
    The University of Texas Health Science Center at San Antonio

    See if you can join NCT05057806 on ClinicalTrials.gov

  3. Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants

    Our goal of the study is to learn the effects of the diabetes medication named Pioglitazone, in type-2 diabetic obese participants with Heart failure. The main question it aims to answer are: 1. To demonstrate that impaired mitochondrial function leading to reduced ATP generation plays a key pathop…

    Stage
    Phase 4
    Ages
    30 to 70
    Site
    Texas Diabetes Institute/UH, San Antonio, Texas
    Run by
    The University of Texas Health Science Center at San Antonio

    See if you can join NCT05838287 on ClinicalTrials.gov

  4. Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

    Heart failure with preserved ejection fraction (HFPEF) is common and deadly but without therapy. Inconclusive studies such as TOPCAT (Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist) suggest spironolactone may be effective in HFPEF, but it is generic and will no…

    Stage
    Phase 3
    Ages
    50 to 99
    Site
    University of Texas Health Science Center at San Antonio, San Antonio, Texas
    Locations
    78 in total
    Run by
    Uppsala University

    See if you can join NCT02901184 on ClinicalTrials.gov

How to read this page. Every study here comes from ClinicalTrials.gov, the public registry that research teams are required to file with. We have summarised each one in plain language and shown where it is running. We have not changed what any study says it is doing.

What TrialBoost is. We help people find research that might suit them, and, if they ask us to, we pass their details to the research team running it. We are not a doctor, a research site, or a study sponsor, and we do not decide who takes part in anything. Joining costs nothing and you can change your mind at any point.

Paid placement. Some studies pay us when someone asks to be connected to them. Those are labelled Sponsored wherever they appear, and they only appear when they match what you were actually looking for.