Heart Disease Clinical Trials

17 studies are recruiting for heart disease in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. Personalized Environment and Genes Study

   Despite the overwhelming focus on genetic and genomic causes of human disease over the past two decades, it has been estimated that genetics is currently known to explain only 20% and 40% of the etiology of common disease. Thus, it is becoming increasingly apparent that human disease is a consequen…

   Stage

   Not phased

   Ages

   18 to 120

   Site

   University of North Carolina, Chapel Hill, North Carolina

   Locations

   2 in total

   Run by

   National Institute of Environmental Health Sciences (NIEHS)

   See if you can join NCT00341237 on ClinicalTrials.gov

2. A Study Of Heart Disease Using AI-Enabled Electrocardiography And Focused Cardiac Ultrasound

   A study to evaluate feasibility, diagnostic yield, accuracy, and actionable thresholds of POC, immediate-feedback AI-ECG + AI FoCUS screening for cardiac disease in well described community populations.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Mayo Clinic in Rochester, Rochester, Minnesota

   Run by

   Mayo Clinic

   See if you can join NCT07351656 on ClinicalTrials.gov

3. Reduction or Elimination of Mitral Regurgitation With the SATURN TMVR System (CASSINI-US)

   CASSINI-US is a prospective, single-arm, multicenter early feasibility study enrolling up to 15 patients at up to 5 sites in the United States (US). The purpose of the study is to evaluate the technical (implant) feasibility, and safety, and performance of the SATURN TS TMVR System for the treatmen…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Los Robles Regional Medical Center, Thousand Oaks, California

   Locations

   5 in total

   Run by

   InnovHeart

   See if you can join NCT07130994 on ClinicalTrials.gov

4. Cooperative Assessment of Late Effects for SCD Curative Therapies

   Sickle Cell Disease is one of the most common genetic diseases in the United States, occurring in approximately 1 in 400 births. Approximately 100,000 individuals are diagnosed with SCD in the United States. Mortality for children with SCD has decreased substantially over the past 4 decades, with >…

   Stage

   Not phased

   Ages

   4 to 65

   Site

   Vanderbilt University Medical Center, Nashville, Tennessee

   Locations

   5 in total

   Run by

   Vanderbilt University Medical Center

   See if you can join NCT05153967 on ClinicalTrials.gov

5. A Usability Study of a Multi-channel ECG Monitoring Device

   This study it to evaluate the usability of the WearLinq eWave patch in a general adult population.

   Stage

   Not phased

   Ages

   18 and older

   Site

   ABio Clinical Research Partners, New London, North Carolina

   Run by

   Wearlinq

   See if you can join NCT07388355 on ClinicalTrials.gov

6. Pathways to Prevention Food-is-Medicine Trial

   The goal of this study is to learn whether combining healthy food access with personalized tools can help families improve heart health and make lasting lifestyle changes. The main questions the study aims to answer are: * Do the new tools (PRO-CVH and Triple-C) help families improve their heart he…

   Stage

   Not phased

   Ages

   6 and older

   Site

   Nationwide Children's Hospital, Columbus, Ohio

   Run by

   Amrik Singh Khalsa

   See if you can join NCT07380243 on ClinicalTrials.gov

7. The Relationship Between Blood Flow Readings During Surgery and How Well the Graft Stays Open and How Patients Recover Afterward in Coronary Artery Bypass Graft Surgery

   The purpose of this study is to learn more about a tool called Transit-Time Flow Measurement (TTFM). TTFM uses sound waves during surgery to check how well blood is flowing through blood vessels. This helps doctors see if the blood flow is good during coronary artery bypass grafting (CABG), which i…

   Stage

   Not phased

   Ages

   18 and older

   Site

   Weill Cornell Medicine/NewYork Presbyterian Hospital, New York, New York

   Run by

   Weill Medical College of Cornell University

   See if you can join NCT07485738 on ClinicalTrials.gov

8. Focused Orticumab Research for Treating Inflammation in Coronary Arteries

   The goal of this clinical trial is to determine the clinical effect of orticumab treatment on inflammation in study participants with prior myocardial infarction who have elevated coronary inflammation based on CCTA. The main question it aims to answer is: Clinical effects of orticumab treatment on…

   Stage

   Phase 2

   Ages

   18 and older

   Site

   Abcentra Investigational Site, Torrance, California

   Locations

   41 in total

   Run by

   Abcentra

   See if you can join NCT06927739 on ClinicalTrials.gov

9. Sex Differences in Barriers and Participation in Physical Activity During and Following Cardiac Rehabilitation

   The SPARC study will measure physical activity and functional fitness during cardiac rehabilitation, right after completion of cardiac rehabilitation, and 6 months later. This will help investigators learn if men and women maintain physical activity levels and functional fitness differently during …

   Stage

   Not phased

   Ages

   18 and older

   Site

   Duke Center for Living, Durham, North Carolina

   Run by

   Duke University

   See if you can join NCT07214350 on ClinicalTrials.gov

10. Healthy Living Anson Study

    The goal of this randomized delayed control intervention research study is to see if participants who receive education and healthy prepared meals improve the quality of their diet compared to participants who receive only physical activity education and coaching.

    Stage

    Not phased

    Ages

    18 to 99

    Site

    University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

    Run by

    University of North Carolina, Chapel Hill

    See if you can join NCT07126587 on ClinicalTrials.gov

11. Promoting Physical Activity and Fitness Among Underserved Latino Families Living in U.S.-Mexico Border Regions

    This study has the goal to increase physical activity and fitness among Latinos in San Diego, California and Mexicali, Baja California (U.S.-Mexico border) since these cities have similar diseases such as high rates of heart disease and obesity. Therefore there is a need to have physical activity p…

    Stage

    Not phased

    Ages

    6 and older

    Site

    San Diego State University, San Diego, California

    Run by

    San Diego State University

    See if you can join NCT06596902 on ClinicalTrials.gov

12. Interprofessional Pharmacogenomics (IPGx) Registry and Repository

    This program collects genetic and health information to help doctors choose the right medications for patients.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Texas A&M Family Care, Bryan, Texas

    Run by

    Texas A&M University

    See if you can join NCT06726590 on ClinicalTrials.gov

13. Using CTA Measures to Define Cardiac Risk In NFL Alumni

    The GAMEFILM Registry is a post-market, multi-center, data collection study assessing the presence of CAD in NFL alumni.

    Stage

    Not phased

    Ages

    Any age

    Site

    Boone Heart Institute, Greenwood Village, Colorado

    Run by

    HeartFlow, Inc.

    See if you can join NCT06831409 on ClinicalTrials.gov

14. Diet and Active Lifestyle - Yuuyaraq (The Yup'ik Way of Life)

    Heart disease is the leading cause of death for Alaska Native men and the second leading cause of death (after cancer) among women and Alaska Native people overall. The overarching goal of the proposed multilevel, multicomponent intervention, Diet and Active Lifestyle - Yuuyaraq (DAiLY), is to redu…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Yukon-Kuskokwim Health Corporation, Bethel, Alaska

    Locations

    2 in total

    Run by

    Oregon Health and Science University

    See if you can join NCT06629610 on ClinicalTrials.gov

15. Studies of Neuregulin/ERBB Signaling in Human Heart

    This study examines the role of the epidermal growth factor (EGF) receptor family and the EGF family of ligands in the regulation of non-myocytes isolated from the human heart.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Maine Medical Center, Portland, Maine

    Run by

    Douglas B. Sawyer

    See if you can join NCT02820233 on ClinicalTrials.gov

16. Dilated Cardiomyopathy Detection Using AI and Screening With Mobile Technology (DCM-DETECT)

    This is a prospective, single-arm clinical trial in which participants with dilated cardiomyopathy will invite their first degree relatives to undergo mobile cardiac, electrocardiogram screening.

    Stage

    Not phased

    Ages

    18 and older

    Site

    Lancaster General Hospital, Lancaster, Pennsylvania

    Run by

    Lancaster General Hospital

    See if you can join NCT06688396 on ClinicalTrials.gov

17. Heart Disease of the Small Arteries in Women and Men

    Women suffer disproportionately than men from Cardiac Syndrome X ( chest pain in the absence of flow limiting coronary artery stenosis). Coronary microvascular disease is hypothesized to mediate chest pain in this syndrome. This disorder of the small heart vessels (arterioles) compared to the large…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Cedars-Sinai Women's Heart Center, Los Angeles, California

    Run by

    Cedars-Sinai Medical Center

    See if you can join NCT00573027 on ClinicalTrials.gov