Hearing Loss Clinical Trials

32 studies are recruiting for hearing loss in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. OTC Hearing Aid and MCI

   The goal of this study is to better understand if, in patients with mild to moderate hearing loss who are also experiencing mild cognitive impairment (MCI) or Alzheimer's disease and related dementias (ADRD), Over-the-Counter (OTC) hearing aids: 1. improve communication 2. Whether the magnitude of …

   Stage

   Not phased

   Ages

   60 to 90

   Site

   Northwestern University HA Lab, Evanston, Illinois

   Locations

   3 in total

   Run by

   Northwestern University

   See if you can join NCT06112860 on ClinicalTrials.gov

2. Atorvastatin to Reduce Cisplatin-Induced Hearing Loss Among Individuals With Head and Neck Cancer

   Background: Cisplatin is used to treat head and neck cancer. People who take this drug are at risk for hearing loss. Atorvastatin is a drug used to treat high cholesterol. It might reduce the risk of cisplatin-induced hearing loss. Objective: To find out if atorvastatin reduces hearing loss in peop…

   Stage

   Phase 2

   Ages

   18 to 100

   Site

   Winship Cancer Institute at Emory University, Atlanta, Georgia

   Locations

   5 in total

   Run by

   National Institute on Deafness and Other Communication Disorders (NIDCD)

   See if you can join NCT04915183 on ClinicalTrials.gov

3. Listening Effort in Cochlear Implant Users

   People with hearing loss experience extra effort when listening, which can lead to severe psychological barriers to communication and social participation. Listening effort can lead to fatigue, mental strain, burnout, medical sick leave, and the need for increased time to recover from regular daily…

   Stage

   Not phased

   Ages

   18 to 75

   Site

   University of Minnesota, Minneapolis, Minnesota

   Run by

   University of Minnesota

   See if you can join NCT06516575 on ClinicalTrials.gov

4. Collection of Clinical Data and Specimens for Research in Hearing, Balance, Taste, Smell, Voice, Speech, and Language Disorders.

   Background: People with hearing, balance, and taste, smell, voice, speech, language, and other Ear, Nose, and Throat (ENT) disorders may seek treatment at the National Institute on Deafness and Other Communication Disorders (NIDCD). Some of these people may benefit from enrolling in the NIDCD intra…

   Stage

   Not phased

   Ages

   2 to 99

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute on Deafness and Other Communication Disorders (NIDCD)

   See if you can join NCT05670496 on ClinicalTrials.gov

5. Early Age-Related Hearing Loss Investigation (EARHLI)

   Early Age-Related Hearing Loss Investigation (EARHLI) is a single site study that will randomize late middle age adults to either a hearing intervention (including hearing aids) or a health education intervention. Participants will be followed for 1 year. This study will provide information on redu…

   Stage

   Not phased

   Ages

   55 to 75

   Site

   Columbia University Medical Center, New York, New York

   Run by

   Columbia University

   See if you can join NCT06174038 on ClinicalTrials.gov

6. Natural History of Autosomal Dominant Hearing Loss

   Background: Hereditary hearing loss is one of the most common sensory disabilities affecting newborns. The main options for people with hereditary hearing loss are hearing aids and cochlear implants. Both options have their limitations and do not restore biological hearing. Researchers want to lear…

   Stage

   Not phased

   Ages

   3 to 99

   Site

   National Institutes of Health Clinical Center, Bethesda, Maryland

   Run by

   National Institute on Deafness and Other Communication Disorders (NIDCD)

   See if you can join NCT04501081 on ClinicalTrials.gov

7. Investigation of a Device to Deliver Intra-Operative Therapeutic Hypothermia for Hearing Preservation in Cochlear Implantation

   The goal of this interventional clinical study is to investigate the use of mild therapeutic hypothermia for preservation of residual hearing in cochlear implant surgery. The main questions the trial aims to answer are: 1. Is mild therapeutic hypothermia safe for use during cochlear implantation? 2…

   Stage

   Not phased

   Ages

   18 and older

   Site

   University of Miami, Miami, Florida

   Run by

   Restorear Devices LLC

   See if you can join NCT06375278 on ClinicalTrials.gov

8. Evaluation of Clinical Outcomes of Ponto Procedures Performed in Settings Outside the Main Operating Room (i.e. Out-of-OR)

   This study is a combined retro- and prospective, single arm, multicentre investigation designed to follow clinical practice for Ponto-implantations performed out of OR. The overall objective is to investigate the complication rate for procedures performed out-of-OR.

   Stage

   Not phased

   Ages

   18 and older

   Site

   Northern California Veterans Affairs Healthcare System, Sacramento, California

   Locations

   6 in total

   Run by

   Oticon Medical

   See if you can join NCT06930781 on ClinicalTrials.gov

9. Cochlear Implants in Young Children With SSD

   The goal of this clinical trial is to investigate the safety and effectiveness of cochlear implantation in infants and toddlers with single-sided deafness. The main questions it aims to answer are: * Are cochlear implants an effective treatment of single-sided deafness in infants and toddlers? * Ar…

   Stage

   Not phased

   Ages

   0 to 5

   Site

   The Children's Cochlear Implant Center at UNC, Durham, North Carolina

   Run by

   University of North Carolina, Chapel Hill

   See if you can join NCT05775367 on ClinicalTrials.gov

10. SPI-1005 in Adults Receiving Cochlear Implant

    The goal of this clinical trial is to learn about the effects of drug SPI-1005 in adults receiving a cochlear implant with a long electrode array (FLEX26 or greater) from MED-EL Cochlear Implant Systems into one ear. The main question this clinical trial aims to answer is: Is drug SPI-1005 safe and…

    Stage

    Phase 2

    Ages

    18 and older

    Site

    University of Iowa, Iowa City, Iowa

    Locations

    6 in total

    Run by

    Sound Pharmaceuticals, Incorporated

    See if you can join NCT06340633 on ClinicalTrials.gov

11. Perception of Speech in Context by Listeners With Healthy and Impaired Hearing

    Recognition of speech sounds is accomplished through the use of adjacent sounds in time, in what is termed acoustic context. The frequency and temporal properties of these contextual sounds play a large role in recognition of human speech. Historically, most research on both speech perception and s…

    Stage

    Not phased

    Ages

    18 to 65

    Site

    University of Minnesota, Minneapolis, Minnesota

    Locations

    2 in total

    Run by

    Marquette University

    See if you can join NCT06465979 on ClinicalTrials.gov

12. School Screening and Telemedicine Specialty Referral to Address Childhood Hearing Loss in Rural Kentucky

    This trial will evaluate a multilevel intervention (STAR model) that combines mobile health (mHealth) hearing screening tools with telemedicine technology for specialty care access in rural Kentucky schools. An initial version of the model was used in rural Alaska where telemedicine-based specialty…

    Stage

    Not phased

    Ages

    3 to 11

    Site

    University of Kentucky, Lexington, Kentucky

    Run by

    University of Arkansas

    See if you can join NCT05513833 on ClinicalTrials.gov

13. School Screening and Telemedicine Specialty Referral to Address Childhood Hearing Loss in Rural Alaska

    The prevalence of childhood hearing loss in rural Alaska is disproportionately high and predominately infection-related. With preventive screenings and access to health care, much of childhood hearing loss is preventable. Although state-mandated school screening helps identify children with hearing…

    Stage

    Not phased

    Ages

    3 to 21

    Site

    Southcentral Foundation, Anchorage, Alaska

    Run by

    University of Arkansas

    See if you can join NCT05593484 on ClinicalTrials.gov

14. Extra-cochlear Electrode Placement at the Post-auricular Vagus Nerve in Cochlear Implantation

    This study will evaluate hearing outcomes after cochlear implantation with placement of the ECE1 ground electrode near the post-auricular vagus nerve (Arnold's nerve) to assess non-inferiority with respect to placement under the temporalis muscle.

    Stage

    Not phased

    Ages

    18 and older

    Site

    NYU Langone Health, New York, New York

    Run by

    NYU Langone Health

    See if you can join NCT07011927 on ClinicalTrials.gov

15. A Treatment for a Form of Age-Related Central Auditory Processing Disorder Consisting of Clemastine Fumarate Plus Engineered Sound

    The goal of this clinical trial is to determine the efficacy of Clemastine Fumarate in the presence of engineered sound to treat age-related central auditory processing disorder (CAPD). This disorder impacts 800M patients worldwide, including ~1/3 people over 40 years of age and ~1/2 people over 65…

    Stage

    Phase 1

    Ages

    45 to 65

    Site

    University of Colorado Anschutz Medical Center, Aurora, Colorado

    Run by

    University of Colorado, Denver

    See if you can join NCT07304024 on ClinicalTrials.gov

16. Fall Risk Assessment and Speech Intelligibility Enhancement Using In-ear Device

    The purpose of this study is to develop and validate methods to use hearing aids equipped with embedded sensors and artificial intelligence to assist in the assessment of fall risk and in the implementation of interventions aimed at reducing the risk of falling, as well as to improve speech intelli…

    Stage

    Not phased

    Ages

    55 and older

    Site

    Stanford Ear Institute, Palo Alto, California

    Run by

    Stanford University

    See if you can join NCT05365646 on ClinicalTrials.gov

17. Testing the Addition of Pedmark to Cisplatin Chemotherapy for Reducing Drug-Induced Ear Damage in Men With Stage II-III Metastatic Testicular Germ Cell Tumors

    This phase I trial evaluates whether adding Pedmark to standard of care cisplatin-based chemotherapy reduces drug-induced ear damage (ototoxicity) in men with stage II-III testicular germ cell tumors that have spread from where they first started (primary site) to other places in the body (metastat…

    Stage

    Phase 1

    Ages

    18 and older

    Site

    City of Hope Medical Center, Duarte, California

    Run by

    City of Hope Medical Center

    See if you can join NCT07218913 on ClinicalTrials.gov

18. Improving Speech in Noise Using Noninvasive Stimulation

    Traumatic brain injury, a common injury in military service personnel, often leads to poor processing of speech in noisy environments. The goal of the current study is to better understand the brain basis for this difficulty and evaluate a new approach to improving speech in noise perception.

    Stage

    Not phased

    Ages

    25 to 55

    Site

    UF Health at the University of Florida, Gainesville, Florida

    Run by

    University of Florida

    See if you can join NCT07176936 on ClinicalTrials.gov

19. AI Noise Reduction in Phonak Hearing Aids

    The purpose of this study is to determine if artificial intelligence- based noise reduction can offer objective improvement in hearing and speech perception for hearing impaired patients.

    Stage

    Not phased

    Ages

    18 to 110

    Site

    Mayo Clinic in Rochester, Rochester, Minnesota

    Run by

    Mayo Clinic

    See if you can join NCT06743295 on ClinicalTrials.gov

20. Preschool Hearing Screening

    Children who are deaf or hard-of-hearing (D/HH) are at risk of speech and language delays, which can be mitigated through early identification and intervention. Identifying hearing loss (HL) during preschool is crucial, but the most effective hearing screening method for preschoolers remains uncert…

    Stage

    Not phased

    Ages

    2 to 6

    Site

    The University of California, San Francisco, San Francisco, California

    Run by

    University of California, San Francisco

    See if you can join NCT06058767 on ClinicalTrials.gov

21. HEARS-NPS: Addressing Hearing Loss as a Common Unmet Contributor of Neuropsychiatric Symptoms

    This randomized controlled trial study aims to evaluate a revised hearing care intervention for older adults with Alzheimer's Disease and Related Dementias (ADRD). The community-delivered hearing care intervention utilizes tailored strategies to assess impact on communication, neuropsychiatric symp…

    Stage

    Not phased

    Ages

    60 to 100

    Site

    Johns Hopkins Memory and Alzheimer's Treatment Center, Baltimore, Maryland

    Run by

    Johns Hopkins University

    See if you can join NCT06930560 on ClinicalTrials.gov

22. NIDCD Otolaryngology Clinical Protocol Biospecimen Bank

    Background: Many disorders of the head and neck can affect a person s hearing; balance; smell; taste; swallowing; voice; or speech. These disorders include cancers and genetic and inflammatory diseases. To find better ways to diagnose and treat these disorders, researchers need to study tissues and…

    Stage

    Not phased

    Ages

    3 to 99

    Site

    National Institutes of Health Clinical Center, Bethesda, Maryland

    Run by

    National Institute on Deafness and Other Communication Disorders (NIDCD)

    See if you can join NCT06303180 on ClinicalTrials.gov

23. Quantification of Visually Evoked Cortical Potentials in Individuals With Hearing Loss

    This research is being done to determine whether a test that measures a "Visual Evoked Potential" can be used in a new way for individuals that have hearing loss. This test measures the participant's brain's response (so called "brain waves") to specific visual images. This study will help the inve…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire

    Run by

    Dartmouth-Hitchcock Medical Center

    See if you can join NCT05107466 on ClinicalTrials.gov

24. Hearing Impairment, Strategies and Outcomes in VA Emergency Departments

    HearVA involves six VA facility emergency departments (ED) over a 3-year intervention period. The first part of this study will test whether providing personal amplifiers to Veteran ED patients who self-report hearing difficulty is acceptable to these patients, can improve their hearing, enhance un…

    Stage

    Not phased

    Ages

    60 and older

    Site

    Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora, Colorado

    Locations

    6 in total

    Run by

    VA Office of Research and Development

    See if you can join NCT05028972 on ClinicalTrials.gov

25. Combined Electric and Acoustic Hearing (EAS) in Children and Adults

    Cochlear implants are surgically implanted devices which restore the ability to hear to the hearing impaired. Improvements in surgery and electrodes have results in an increased number of adults and children who have residual hearing and can benefit from electric and acoustic hearing in the same ea…

    Stage

    Not phased

    Ages

    5 and older

    Site

    Hearts for Hearing, Edmond, Oklahoma

    Locations

    4 in total

    Run by

    Hearts for Hearing

    See if you can join NCT05923203 on ClinicalTrials.gov