Healthy Aging Clinical Trials

25 studies are recruiting for healthy aging in the United States right now. Each one is listed on ClinicalTrials.gov, the public registry the research teams themselves file with. TrialBoost is not a doctor, a research site, or a study sponsor: the research team decides who takes part.

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Studies now recruiting

1. The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health

   The goal of this clinical trial is to learn if Quercefit® or Ubiqsome™ can improve markers of healthy aging, blood sugar control, and heart health in older adults. It will also learn about the safety of these supplements. The main questions it aims to answer are: 1. Do Quercefit® or Ubiqsome™ impro…

   Stage

   Not phased

   Ages

   50 to 75

   Site

   The Applied Science and Performance Institute, Tampa, Florida

   Run by

   Applied Science & Performance Institute

   See if you can join NCT07760506 on ClinicalTrials.gov

2. Effects of Freeze-dried Grape Powder on Immune Profiles in Healthy Aging Adults

   The purpose of this study is to investigate the effects of consuming grape powder on immune profiles in healthy middle- and older-aged individuals. Specifically, the investigators are interested in evaluating the potential effects of grapes in influencing markers of immune function, inflammation, a…

   Stage

   Not phased

   Ages

   50 to 75

   Site

   Department of Nutritional Sciences, Storrs, Connecticut

   Run by

   University of Connecticut

   See if you can join NCT07079982 on ClinicalTrials.gov

3. Reactive Balance Training for Fall Prevention

   The objective of this pilot study is to evaluate and compare the effect of three different perturbation based training devices on the reactive balance control among healthy young adults, healthy older adults, and neurologically impaired stroke individuals. Furthermore, the project aims to determine…

   Stage

   Not phased

   Ages

   18 to 90

   Site

   University of Illinois at Chicago, Chicago, Illinois

   Run by

   University of Illinois at Chicago

   See if you can join NCT04205279 on ClinicalTrials.gov

4. Effects of Miricell Supplementation on Biomarkers of Healthy Aging and Autophagy

   The goal of this clinical trial is to learn if a dietary supplement called Miricell works to improve cellular health and signs of healthy aging in adults. It will also learn about the safety of Miricell. The main questions it aims to answer are: * Does Miricell improve markers of autophagy, which i…

   Stage

   Not phased

   Ages

   40 to 70

   Site

   The Center for Applied Health Sciences, Canfield, Ohio

   Run by

   Nutraland USA, Inc.

   See if you can join NCT07675200 on ClinicalTrials.gov

5. Multivitamin and Mineral Supplementation and Healthy Aging

   The goal of this study is to determine the impact of MVM supplementation on clinical and biochemical markers associated with healthy aging, with a particular focus on mitochondrial function and metabolism. Specifically, changes in mitochondrial respiration using isolated blood cells will be measure…

   Stage

   Not phased

   Ages

   40 to 60

   Site

   University of California, San Diego, La Jolla, California

   Run by

   University of California, San Diego

   See if you can join NCT07642869 on ClinicalTrials.gov

6. Assessing the Influence of Habitual Beef Intake on Key Molecular Markers of Brain Health

   his study investigates whether eating lean beef every day can help support brain health and healthy aging in older adults. As people age, protecting memory and cognitive function becomes increasingly important. Lean beef is a rich source of essential nutrients-such as vitamin B12, iron, zinc, and c…

   Stage

   Not phased

   Ages

   65 and older

   Site

   South Dakota State University, Brookings, South Dakota

   Run by

   South Dakota State University

   See if you can join NCT07623785 on ClinicalTrials.gov

7. Hormones, Outcomes, and Pain Pathways in Exercise Study

   The goal of the proposed project is to evaluate a mechanical intervention (sports bras designed specifically for full busted women) to alleviate neck, shoulder, arm, and back pain in full-busted women and investigate the contribution of non-mechanical pathways associated with this type of pain in w…

   Stage

   Phase 1

   Ages

   18 to 60

   Site

   University of Houston, Houston, Texas

   Run by

   University of Houston

   See if you can join NCT07579182 on ClinicalTrials.gov

8. Swallowing Impairments in Adults With and Without Alzheimer's Disease

   This research study is investigating whether people with Alzheimer's disease (AD) experience more changes to swallowing than their healthy age-matched peers. The prevalence of swallowing impairments in moderate-severe AD is high (85-93%), yet little is known about how swallow function evolves throu…

   Stage

   Not phased

   Ages

   60 and older

   Site

   Vanderbilt University Medical Center, Nashville, Tennessee

   Run by

   Vanderbilt University Medical Center

   See if you can join NCT06678100 on ClinicalTrials.gov

9. African Americans (AA) Communities Speak

   African Americans are less likely to receive quality end-of-life (EoL) care. Addressing disparities in EoL care will need efforts to support a better understanding of African American patients' EoL cultural values and preferences for EoL communication and the impact of historical and ongoing care d…

   Stage

   Not phased

   Ages

   Any age

   Site

   UAB, Birmingham, Alabama

   Locations

   2 in total

   Run by

   University of Alabama at Birmingham

   See if you can join NCT05908487 on ClinicalTrials.gov

10. iVS-1 Probiotic Intervention Targeting Biological Aging in Midlife Adults

    This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effects of Bifidobacterium adolescentis (iVS-1) supplementation on biological aging markers, metabolic health, and functional health outcomes in midlife adults. The study explores whether modulation…

    Stage

    Not phased

    Ages

    40 to 75

    Site

    MusB Research LLC, New Port Richey, Florida

    Run by

    Synbiotic Health

    See if you can join NCT07407894 on ClinicalTrials.gov

11. Neuromodulation and Fatigue

    In this project, we aim to determine any potential effects of a weak electrical current applied to the neck or thoracic area on functional capacity and muscle activation. Healthy individuals will participate in one familiarization followed by up to 6 experimental sessions. Fatigability and motor fu…

    Stage

    Not phased

    Ages

    18 to 50

    Site

    University of Oklahoma, Norman, Oklahoma

    Run by

    University of Oklahoma

    See if you can join NCT05487131 on ClinicalTrials.gov

12. Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD

    The goal of this study is to objectively test one's sense of smell, called olfaction, in participants with Subjective Cognitive Concerns (SCC), Mild Cognitive Impairment, Mild Behavioral Impairment (MBI), and age-matched controls. The main question it aims to answer is whether the AROMHA Brain Heal…

    Stage

    Not phased

    Ages

    18 to 100

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT05881239 on ClinicalTrials.gov

13. Exercise to Improve Brain Health in Older African Americans

    The goal of this clinical trial is to test the effects of different types of exercise on brain health and Alzheimer's risk in older African Americans. Specifically, the main question[s] it aims to answer are: * What is the effect of a Cardio-Dance Fitness (CDF) vs. a Strength, Flexibility, and Bala…

    Stage

    Phase 2

    Ages

    60 and older

    Site

    Rutgers, The State University of New Jersey - Newark campus, Newark, New Jersey

    Run by

    Rutgers, The State University of New Jersey

    See if you can join NCT05597124 on ClinicalTrials.gov

14. TMS for Cognitive Decline in Aging and Preclinical AD

    In this research study we want to learn more about the effects of non-invasive brain stimulation on motivation, memory, and brain-network function in cognitively unimpaired older adults and individuals with preclinical Alzheimer's disease. This study will use a form of non-invasive brain stimulatio…

    Stage

    Not phased

    Ages

    40 to 99

    Site

    Massachusetts General Hospital, Boston, Massachusetts

    Run by

    Massachusetts General Hospital

    See if you can join NCT06956300 on ClinicalTrials.gov

15. Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study

    Developing efficient cognitive intervention for cognitively health older adults is a major public health goal, due to its potential for reducing age-related cognitive decline and Alzheimer's disease/dementia risk. Executive Control is a relevant cognitive target since it declines with aging and is …

    Stage

    Not phased

    Ages

    60 to 75

    Site

    Rutgers New Jersey Medical School, Behavior Health Sciences Building, F-Level, Newark, New Jersey

    Run by

    Rutgers, The State University of New Jersey

    See if you can join NCT06995638 on ClinicalTrials.gov

16. Role of Autophagy in Type 2 Diabetes Microvascular Dysfunction

    The goal of this clinical trial is to examine the role of autophagy on microvascular function in adults with Type 2 Diabetes. The main question it aims to answer are: * Does presence of Type 2 Diabetes reduce autophagy and impair microvascular function? * Does exposure to high glucose impair autoph…

    Stage

    EARLY_Phase 1

    Ages

    18 to 80

    Site

    Medical College of Wisconsin, Milwaukee, Wisconsin

    Run by

    Medical College of Wisconsin

    See if you can join NCT05593549 on ClinicalTrials.gov

17. Cognitive Vitality Pilot Study

    This study's purpose is to evaluate the effects of a dietary supplement on cognitive function and psychological well-being in community-dwelling older adults aged 55+. The study involves taking a commercially available dietary supplement daily for 45 days. A 45-minute assessment will be conducted a…

    Stage

    Not phased

    Ages

    55 and older

    Site

    Community, West Palm Beach, Florida

    Run by

    Arizona State University

    See if you can join NCT07208279 on ClinicalTrials.gov

18. Effect of Vestibular Perceptual Learning on Vestibular Thresholds and Balance

    The intervention being studied is a minimal risk perceptual learning protocol delivered in an academic laboratory setting; the goal of the intervention is to improve the perception of passive whole-body tilts and/or translations, as well as balance, by providing feedback following passive tilts or …

    Stage

    Not phased

    Ages

    65 to 89

    Site

    The Ohio State University Wexner Medical Center, Columbus, Ohio

    Run by

    Ohio State University

    See if you can join NCT05818787 on ClinicalTrials.gov

19. The Mitopure Challenge to Detect Levels of Urolithin A in Dried Blood Spots

    Open labelled, virtual home based study to assess the test repeatability and the failure/rejection rate of the samples collected at home by participants.

    Stage

    Not phased

    Ages

    18 to 80

    Site

    Amazentis USA, San Francisco, California

    Run by

    Amazentis SA

    See if you can join NCT04985630 on ClinicalTrials.gov

20. Absorption and Tolerability of Injectable Administration of Niagen®+, as Compared to NAD+

    This study evaluates the subjective effects of injection administration of NR on healthy adult populations.

    Stage

    Not phased

    Ages

    40 to 65

    Site

    Nutraceuticals Research Institute, Huntsville, Alabama

    Run by

    Nutraceuticals Research Institute

    See if you can join NCT06919328 on ClinicalTrials.gov

21. Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging

    The study will examine whether 5mg melatonin (over the counter, OTC) over a 9-month period improves Alzheimer's disease (AD) biomarkers and cognitive function in two groups of individuals: those with mild cognitive impairment (MCI+) and those who are not (MCI-). AD biomarkers will be measured from …

    Stage

    Not phased

    Ages

    56 to 85

    Site

    University of Iowa Hospitals & Clinics, Iowa City, Iowa

    Run by

    Natalie Denburg

    See if you can join NCT03954899 on ClinicalTrials.gov

22. Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia

    The proposed research is relevant to public health because stroke is a leading cause of long-term disability among older adults and communication impairments resulting from stroke have a significant negative impact on quality of life. By seeking to better understand post-stroke aphasia, this projec…

    Stage

    Not phased

    Ages

    18 and older

    Site

    University of Maryland, College Park, Maryland

    Run by

    University of Maryland, College Park

    See if you can join NCT06405594 on ClinicalTrials.gov

23. Balance Control and Recovery in Diabetes Peripheral Neuropathy

    In this study the effects of diabetic peripheral neuropathy will be assessed on balance control, balance recovery, and muscle electrical activity in adults over 50 years. Aim 1: Determine muscle activity and balance control during a sit-to-stand in adults age above 50 with and without diabetic peri…

    Stage

    Not phased

    Ages

    50 to 99

    Site

    The University of Texas at Austin, Austin, Texas

    Run by

    Lisa Griffin

    See if you can join NCT06544876 on ClinicalTrials.gov

24. Effect of Beet-root Juice and PBM Treatments on Muscle Fatigue

    The goal of this randomized counterbalanced repeated measures study is to test beet-root juice supplementation and red light therapy augment forearm muscle endurance in apparently healthy older adults over 65 years of age. The main questions seek to answer the following question: Does beet-root jui…

    Stage

    Not phased

    Ages

    65 and older

    Site

    Wake Forest Univesity, Winston-Salem, North Carolina

    Run by

    Wake Forest University

    See if you can join NCT05596474 on ClinicalTrials.gov

25. MS-ResearchBiomarkerS

    This study is being conducted to investigate risk factors for disability progression in Multiple Sclerosis and related disorders (MSRD). The primary goal is to assess whether combining information from visual assessment, blood markers, as well as historical and ongoing longitudinal MRIs of the brai…

    Stage

    Not phased

    Ages

    18 and older

    Site

    Cedars-Sinai Medical Center, Los Angeles, California

    Run by

    Cedars-Sinai Medical Center

    See if you can join NCT05204459 on ClinicalTrials.gov